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408795 tn?1324935675

Oral HepC clinical trials?

I have read about a couple of pioneer companies having clinical trials with tablets only tx.  Does anyone know if interferon is being eliminated in those trials or are they making interferon tablets.  Any info or links would be appreciated.
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1751426 tn?1399007484
Boehringer Ingleheim is doing a phase III study with two oral drugs +NO interferon.  Both these drugs are letter/number names.  BI 201335, its investigational once-daily oral protease inhibitor plus BI 207127, a polymerase inhibitor,  Here is a link:
http://hepatitiscnewdrugs.blogspot.com/2011/04/hepatitis-c-compound-bi-201335-moves.html
Hope this helps.
Pauline
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Avatar universal
They really mean - no interferon.  No tablets, nada.  See Pharmasset and PSI-7977.
Nice to see you here again!
dointime
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408795 tn?1324935675
Good to see you too!  This is great information for alot of people who can't handle the interferon or needles.  I'm hoping there are other options heading our way as well.  It's great to see that California Drug Mfg are getting into the act of curing HepC as well.  More companies could potentially lead to more cures!!  That's a win win for everyone!!  Yay!!    
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Avatar universal
I am currently in an all oral study by Gilead.  Day 10.  Feel great.  Few mild sides when I started but none in about a week.  VL went from 70k to 600 in first 24 hours.  Should get 7 day VL numbers in next few days and hoping it's gone.  Good luck!
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408795 tn?1324935675
Very impressive, super quick acting meds!  WTG!  Keep us posted!  
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Avatar universal
I'm also doing an oral clinical trial. It is a Roche quad oral phase 2b trial.
I started 11 days ago and have minimal sides, just headaches if I don't drink enough water.
I had a VL three days ago so waiting those results!
The trial includes: Danoprevir, Ritonavir, RO5024048, & Ribas. There are 3 arms in my group, (non responders & relapsers) one has the all orals with no Ifn, two include Ifn.
This is only for 24 wks.
This Roche trial is going world wide :)
Hope so much this works, I'm a 3 time non responder with high VL, low fibrosis 1-2.
Fingers crossed !!
from Ozgirl x
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Avatar universal
I'm (hopefully) starting this trial in the next few weeks:

http://www.hivandhepatitis.com/hep_c/news/2011/0603_2011_a.html

DAA combination therapy, all oral, with or without ribavirin. INF is available as a rescue drug.

Good things on the horizon! It's just a matter of how far off that horizon is...
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