Aa
A
A
A
Close
Hepatitis C Community
13.4k Members
Avatar universal

Peg-Intron or Pegasus

I am about to start my third round of treatment.

I have my choice of Pegasus or Peg Intron. Has there been any evidence which one has fewer sides.
I have had Rebitron thearapy also 2 months of Peg-Intron and ribo 2 years ago. I had to stop Peg-Intron because of sides.


                 Thanks,

                   Tony Z
27 Responses
Avatar universal
Tony I am on Pegasys co-peg and sides have been manageable. I never did try pegintron so I don't know the difference. From what I have read on this site and others it sounds like Pegasys has a little better edge than Pegintron and that is why I chose Pegesys. My opinion only. Good luck whatever you do.

Bob
Avatar universal
I've done both and found Pegasys much easier to tolerate. That's been my experience. Mike
29084 tn?1283659640
Hi there Tony .... I am on Pegasys & only know what I read & hear from others on Pegintron .... Pegasys is more forgiving ...  Here's some Info for you Tony, its very good reading <a href="http://janis7hepc.com/pegintron_or_pegasays.htm">PegIntron or Pegasys</a>  ... Good luck All, stay focused on our goal <b>...Steve...</b>
Avatar universal
I did the Intron A/Rebatol combo (3 shots/week + Riba) manufactured by Schering 3 years ago.  Had to quit after 7 weeks due to severe sides.  I did alot of research on both Peg-intron (Schering) and Pegasys (Roche) as well as seeing lots of posts here on the subject before deciding to retreat.  I decided to try the Pegasys product and for me, it's been much more tolerable then the old treatment.  I'm a 1a and did shot 10/48 last night.  Haven't missed a day of work (darn!) and get out for walks, yoga and such.  I also like the fact that Pegasys comes in a vial pre-mixed.  The Pegintron comes in powdered form and has to be mixed with sterile water.  There have also been studies (UCSF) showing the Pegasys product stays in the bloodstream longer then Pegintron.  The Pegasys may be more helpful to type 1's, but both work.  

Avatar universal
Another good thing about Pegasys is that it come in pre-filled syringes or vials so there is no mixing. The prefilled syringes are really nice, and theres no mess ups.  God luck this time!   Joni
Avatar universal
Intron A and Peg-Intron seem to have the most sides.  My husband did the 3X week pre-mixed Intron and I did Peg-Intron and had to mix it.  They both gave us a run for it.  But we made it and are still undetectable.  If I need to do this again, I'd choose Pegasys, I think.  More people, it seems, have fewer sides on it.  **Hopiangel**
Avatar universal
GOOD EVENING TO ALL....I JUST TOOK MY 6TH PEGASYS SHOT....DOES ANYONE KNOW WHAT HAPPENS IF I HIT A VEIN AND THE SHOT MIXED WITH BLOOD AND I PROCEEDED ANYWAY... WOULD IT BE AN UNEFFECTIVE  SHOT?.... THE KIT COMES WITH ONLY FOUR  VIALS AND THERE ARE NO EXTRAS..... THANK YOU ..... EDGAR
Avatar universal
I didn't ask for them, but I get My meds delivered in the Middle of North Dakota and the L.P.N. ordered em. I wasn't gonna complain!!!   Joni
Avatar universal
I shoot the whole thing.  Why waste it?  I never can play by the rules.
Avatar universal
what is bd46?
Avatar universal
I had blood in my last shot. I use the pre-filled syringes, and there is a tiny air-bubble that shows blood. there was such a tiny bit (and I'm too cheap to pay for 4 more syringes) I went ahead and used it. No problem, no bruise, and when I told my P.A. today, she said, no problem.   Joni
Avatar universal
Befuddled & others, scroll back down a bit to Update/GIPA, I have a question for you and others at the end of post- Thank's-- Harley Dude
29837 tn?1414538248
I've been through three treatments and I will say I notice very little difference between Peg Intron and Pegasys. The side effects are nominally and very minimally changed and you will still have to deal with your temper and exhaustion and other weirdness. I guess I was lucky I didn't have to go on tranquilizers for the volatile temper fits. Avoid arguments, pinheads, enraged drivers, ex's and morons at all cost while on treament. I was also on Amantadine as well, but unfortunately, in my case nothing works. Luckily, I'm not progressing from stage 2 Fibrosis. I'm waiting for the Protease Inhibitors clinical trial to begin in this country. Canada and Germany are on their trials. Hopefully, the FDA will not drag their feet regarding this "wonder drug". Saying it like it is....

Good luck,

Magnum
Avatar universal
thread subject change


ordering meds on the internet

i would be extremely reluctant about ordering any meds thru the net..what makes you think you are actually getting the product that is advertised..quality control is an issue, fraudulent products are rampant out there...is the med from the manufacture or some dirty bathtub of a third world country....be careful
Avatar universal
I did my first shot of Peg-Intron last night, and have Rebetrol, 3 doses now of 4000mg each. I've not had any sides as far as I can tell. Drowsey from the Benedryl is all so far. I'm kkeping my fingers crossed.

Good Luck.....
Avatar universal
Thanks for the infomation, I really appreciate the responces. I have been posting and reading here for many years and have seen some grerat advice and bonding. Both are interferons and as such are going to have sides.

  While on treatment I responed but cannot obtain a SVR, also the side's really hit me hard.

"magnum" I too am hoping the Protease Inhibitors get here soon, as I am at stage 3 fibrosis and like millions would really like a differant treatment.

Here is a link to the news about the FDA approval of pegasys in
Pre-Filled syringes

http://www.hepatitisneighborhood.com/content/in_the_news/archive_1554.aspx

              God Bless,

                 Tony Z
Avatar universal
The only adverse affect I had from the Hep A/B vaccines was in getting the dr's office to file the claim using the correct diagnosis code so insurance would pay.  They haven't gotten it right yet.
....Just seemed like a normal shot to me; no sx or anything.  And I got my first 2 boosters after I actually had started tx.  Get my 3rd booster in April.
Avatar universal
Sorry to butt in with what may seem an inane question (although inanity is one of my specialties):

My doc told me to go get immunized for Hep A and get a Hep B booster.  No problem - but I wonder if any of you did took these immunizations and when you did, did you have any adverse effects from it (i.e. did you feel sick afterward, etc.).  I'm trying to be conservative with my sick leave and wonder if I should schedule the immunizations for a Friday afternoon.

By the way, got the genotype results and I am a "1" but don't know if that's a simple 1 or a 1a or 1b (V/L 2.2 million)or how much that matters.  Been rather difficult to prise info out of the doctor's office - still haven't heard results from the liver scan done on 01/12.  They did say that all other results looked good so that was the positive note.  Biopsy will be Feb. 10.
Avatar universal
I HAD THE A/B IMMUNIZATION BOOSTERS DURING PREVIOUS TREATMENT AND HAD NO SIDE EFFECTS...I PREDICT AND HOPE THE SAME FOR YOU....GOOD LUCK.....EDGAR
Avatar universal
i had the hep a shots a few years ago, no problems. I've had 2 of the 3 hep b shots so far while doing tx, also no problems at all.
Avatar universal
I've had 2 of three and had no problems. I take the 3rd in 4 mos., and I don"t expect any problems then either. My doc is si good, he not only doesn't bruise me, the shot didn't hurt  either.He also gave me my flu shot sand pnuemonia shot w/ the same results. Hope you have the same kinda luck.     joni
Avatar universal
Thanks for the info - don't want to sound like a woose but I've had  less than pleasant reactions to flu and tetanus shots, and just wanted to avoid a mis-step if I could.  It is wonderful of you to share your experience and lend your guidance to us 'newbies.'
Avatar universal
Hubby did both.....Peg intron was the worst.
Pegasy was much easier.!!!!!!!!!!!!!!!!!!!!!!!

Shebee
Avatar universal
I'm on Pegasys & Riba, it's my 5th week. Can't say the treatment affected me that badly. No weight loss (I should be so lucky!), no depression, no joints pain. Ho9wever, I do feel more tired sometimes, get headaches, and also I developed mouth ulcers and my tongue bleeds after I brush my teeth. Anyone had that?

Anna
Have an Answer?
Top Hepatitis Answerers
317787 tn?1473362051
DC
683231 tn?1467326617
Auburn, WA
Learn About Top Answerers
Didn't find the answer you were looking for?
Ask a question
Answer a few simple questions about your Hep C treatment journey.

Those who qualify may receive up to $100 for their time.
Explore More In Our Hep C Learning Center
image description
Learn about this treatable virus.
image description
Getting tested for this viral infection.
image description
3 key steps to getting on treatment.
image description
4 steps to getting on therapy.
image description
What you need to know about Hep C drugs.
image description
How the drugs might affect you.
image description
These tips may up your chances of a cure.
Popular Resources
A list of national and international resources and hotlines to help connect you to needed health and medical services.
Here’s how your baby’s growing in your body each week.
These common ADD/ADHD myths could already be hurting your child
This article will tell you more about strength training at home, giving you some options that require little to no equipment.
In You Can Prevent a Stroke, Dr. Joshua Yamamoto and Dr. Kristin Thomas help us understand what we can do to prevent a stroke.
Smoking substitute may not provide such a healthy swap, after all.