Wow I just looked on my labs and the LabCorp reference interval is 140 - 415. Mine are normal so I am not sure what the red flag is with HCV meds is.
Here is one of Hector's old posts related to the matter.
He points out that it is the Interferon and not the Riba that causes platelets to decline.
He also points out different doctors have different thresholds for intervention. I am not sure what that intervention there is in terms of a rescue med (other than Interferon dose reduction).
http://www.medhelp.org/posts/Hepatitis-C/low-platelets/show/1710805
http://www.medhelp.org/posts/Hepatitis-C/low-low-platelet-question/show/1642101
I would not panic yet. I have seen some posts on here where platelets have dropped to 50 and they have managed to finish treatment.
Hang tight and someone who has been down that road is sure to post.
The normal reference range for plats in healthy individuals is 150 --450,however they are somtimes reduced substantial by doing HCV therapy as the Interferon results in reduced production of these cells by the bone marrow and this is normal
Th larger platelet is also normal as this is the finding when the bone marrow is racing to keep up production
All this is fine and as iidylic mentions many have had platelet drop to the 50,s and even lower before there is any danger.
Good luck to you and hubby the rest of the way
Will