Hepatitis C Community
13.4k Members
408795 tn?1324939275


I understand that platelets will go down very low when approaching stage 3 or 4 cirrhosis.  Will they go down in a dramitic manner or can a person actually monitor their platelet levels and get on tx when it gets to a certain number?  Is there a better way to guide the progression of HepC than a liver biopsy?

21 Responses
Avatar universal
I have stage 4 and my platelets have been running between 120-140 for the last 15 years. It is not a good way to monitor progression. Why would you wait to treat if you are a Stage 3/4?  It's time to treat now or at least when the protease drugs are available in 2011.
Avatar universal
Sorry, I see you have done treatment before. As a relapser or non-responder, you should wait for telaprevir or boceprevir ujnless you are geno 3 in which case the new drugs won't really help you. You shouldn't progress so fast that itg will too late to wait for the new drugs.
1225178 tn?1318984204
I wouldn't go by what Susie says if I were you. No body can say how fast a person's liver damage will progress. We do know that as we get older, the damage progresses faster, especially after 50. Do you know what stage you are at or are you just guessing that you have progressed this far?

Sorry to say this, but you need a biopsy to see where you are now before you can make an informed decision. We need to remember that there is no guarantee that the new PIs will be out next year.

Avatar universal
As of '08 biopsy showed fret was stage 0.  No way he's anywhere close to cirrhosis.  

Also he is not a relapser or non responder, he had to stop triple therapy early due to other issues.

Fret, if you're worried about yourself and those platelets tanking I doubt you'll have anything to worry about.  


Avatar universal
"I wouldn't go by what Susie says if I were you. No body can say how fast a person's liver damage will progress."

Dianne, everyone is an adult here and no one talks in absolutes. Chances are more than not a person with hep C, even cirrhosis liike myself, will not progress so fast that they can't wait a few months or even a year. We all know that anything can happen regarding an unapproved drug, or a person's liver, but again, chances sre excellent thst the drug will be available in the early to middle of 2011. At the Vertex Advocacy meeting on Nov. 3rd, we were told that everything is on track and ready to go.

Thanks Trinity, I didn't know any of that. Was Fret on one of the protease as his 3rd drug?
Avatar universal
He was on Boce Susie.
Have an Answer?
Top Hepatitis Answerers
317787 tn?1473362051
683231 tn?1467326617
Auburn, WA
Learn About Top Answerers
Didn't find the answer you were looking for?
Ask a question
Answer a few simple questions about your Hep C treatment journey.

Those who qualify may receive up to $100 for their time.
Explore More In Our Hep C Learning Center
image description
Learn about this treatable virus.
image description
Getting tested for this viral infection.
image description
3 key steps to getting on treatment.
image description
4 steps to getting on therapy.
image description
What you need to know about Hep C drugs.
image description
How the drugs might affect you.
image description
These tips may up your chances of a cure.
Popular Resources
A list of national and international resources and hotlines to help connect you to needed health and medical services.
Here’s how your baby’s growing in your body each week.
These common ADD/ADHD myths could already be hurting your child
This article will tell you more about strength training at home, giving you some options that require little to no equipment.
In You Can Prevent a Stroke, Dr. Joshua Yamamoto and Dr. Kristin Thomas help us understand what we can do to prevent a stroke.
Smoking substitute may not provide such a healthy swap, after all.