Protease Inhibitor clinical trials

[patrockwall]

Hi. My name is Pat. I'm from Rockwall, TX. I was diagnosed with Hepatitis C, genotype 1A in 2001. I was in a clinical trial with Ribavirin and Interferon in 2005, but the treatment did not work. Does anyone know of any clinical trials for protease inhibitors coming up in 2008? - in any part of the US? Texas in preferred, but I would be willing to travel anywhere in the US.
Thanks very much in advance!
Pat

[AKHepper]

this thread is 4 years old.

[Mammamo1947]

My name is Marlene. I am also from Rockwall. I have been in the Clinical Trials since 9-1-2011. Dr. Mantray (Liver Institute, Methodist-Dallas) and many others have been monitoring me. The protease inhibitors can cause some unusual side-effects but for me it was worth it. The last 3 labs deemed me with a zero viral count. Since I am also Cirrhotic I will continue with Ribaviran and Interferon until 9-1-2012. Protease was discontinued on my last visit 3-5-2012. My diagnosis for Hep-C was in 2000 and I am 1B genotype. I have been through many treatments but was declared a "non-responder". I thank God for the wonderful doctors at Methodist.

[Trish77]

clinicaltrials.gov with the www in front of it.  No idea why it got bleeped this time and not others.  Argh.

[Dora82_05]

Well, that is good to know. The only thing I knew was Protease. A straight answer, Thank You......Also, they bleeped out whatever the site was you listed. Take Care....

[Trish77]

Dora,

There are tons of CURRENT discussions on this forum about Telaprevir.  That is a protease inhibitor, otherwise known as a PI as Mike Simon pointed out to you in another thread.  

They are currently recruiting for Telaprevir trials.

Take a look at www.****.gov and use the Advanced Search to narrow it down.

[Dora82_05]

I realize this is old post but just in case, I just recently heard about a Protease Inhibitor Trial at MUSC (Medical University of South Carolina) Charleston, SC. I just recently started seeing a Dr Rueben with the Gastro/Hepatology Dept. Don't have any info. Trying to find some info and not finding much here. Good Luck to you. Dora

[jrowlett]

Try the Liver Institute at Methodist Hospital in Dallas.  Dr. Reem Ghalib is the director.  Cheryl Levine, Phd, R.N.,FNP-c  is the research coordinator.  The number is 214-947-4400, option 6 for the Hepatitis Center.  You'll probably talk to Elizebeth or Gloria for an appt.  They're real nice people and they have some trials coming up.  I'm right across the Lake from you.  Good Luck!

[patrockwall]

Thank You. I wish you luck as well. How are you doing? I don't feel bad - I just can't do what I used to do - I run out of energy pretty fast - which frustrates me! I sent an email to Vertex to see if and when they would open their phase 3 on the VX-950 for non-responders and they said they were waiting for regulatory approval and hoped to be offering trials for treatment-naive patients this fall. Maybe next year. Again, good luck to you!

[viaduk]

oops... that should read treatment not "teatment"

[viaduk]

I just met with Dr. Jacobson in NY, and he told me that the upcoming PI trials are currently slated for treatment naive patients. Since we are both nonresponders/relapsers  we may have to wait a little bit. Hopefully, Vertex or Schering will open up one of their trials to those of us who failed to achieve SVR with the current teatments.  Good luck to you.