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149675 tn?1416673133

R7128 1 year post treatment results

Just wanted to drop by and post my results from my 1 year post TX with R7128. I went to see my doctor today and I am still undetectable.

For those that do not know me I was a geno 1a with a high Viral load. My liver biopsy was stage 2 grade 2. I participated in the R7128 phase 1 trial, which consisted of 4 weeks with R7128, peg, and riba. The followed by 44 weeks with peg and riba alone. I had a 6 log drop going undetectable by week 4 and I stayed there ever since.

I apologize for not stopping by and posting more often since my treatment ended. I do occasionally stop in and read the posts. My life has been a blurr since treatment ended as I feel good and I am so busy with the kids and work. I never really have much time to go online anymore....which is actually a good thing when you think about it!

For those in the middle of your treatment, hang in there. I know the Peg and Riba are rough even brutal, but there really is light at the end of the tunnel. Hang tough and ride it out as best you can. If you need a little help with the sides then do what you have to do to see it out. I ended up taking Lexapro, Ambien, Xanax, and Tri-Chlor to deal with all the wonderful sides. I now take nothing and have my life back. Take care and God Bless
22 Responses
Avatar universal
You beat it!
Avatar universal
Wonderful news, encouragement to all of us!
979080 tn?1323433639
great news !

How many mg R7128 were you on ?

b
720656 tn?1311040235
CONGRATULATIONS!!!!!!

Thanks for sharing!
475300 tn?1312423126
Great news, congrats!!

Denise
1010685 tn?1295032636
Congratulations and thank you for the encouraging words :)
Avatar universal
Congratulations and thanks for the update.

A 6 log drop, undetectable by week 4, was so terrific!

Best wishes,

Susan
665963 tn?1360723554
Congrats! And thanks for sharing your success.
29837 tn?1414534648
Great news! Let's hope it lasts forever...

Magnum
Avatar universal
Congrats !!!

Your name says it all. You indeed slayed the dragon. Another dragon DEAD !!!!
Avatar universal
Congratulations on your wonderful news!!!
Stay well,
Mike
Avatar universal
Congratulations! Having life completely fill the space formerly occupied by HCV sure sounds like a cure - but it's great for to hear about your  r7128 success story ( and encouraging for those left out by the 1st gen ns3/4a PIs).
149675 tn?1416673133
thank you for your well wishes i was on 1000 mg of R7128 in combo with the standard peg and riba. Worked like a charm. This trial is in phase II now. Trust me you will be hearing much more about this drug in the future. Telaprevir gets all the attention right now because it is going to approved really soon. Personally I like this drug beter as it has great results without the other sides that Telaprevir has. Don't get me wrong Telaprevir is a great drug but t has it's own issues (sides). This drug does not. the only sides were from the peg and riba trust me.
149675 tn?1416673133
Thank you all so much for the support. It is really nice to see so many familiar names still here! Mike Simon, GSD girl, Port Ann, Copyman, Magnum, and Willing it is great to hear from all of you. You guys a have been an inspiration to so many people over the years. Great to see you guys still here!!!
Avatar universal
congrats on the svr.
238010 tn?1420406272
Great news, D-slayer!  Glad to hear you are enjoying your HCV-free life
317787 tn?1473358451
This is such great news!  I am so happy for you.  It gives me and others hope that there will be a tx for us who relapsed or non responders, etc.
Thank you for sharing your good news!
Dee
Avatar universal
Awesome news......congratulations
Avatar universal
Congratulations!!
     It's great to hear the positives of the program and it's so enlightning to know that it does work!!! Just gotta see it to the end.
Avatar universal
who is in charge if I want to try this medicine

Avatar universal
I have a sister in Africa with hepatitis  c gentype 1. I was wondering how she can participate in this trial
230202 tn?1370793579
Congratulations!
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