If your red blood cell count will tolerated it, I don't see the harm in increasing to 1000mg, as it is the standard SOC for treatment. There are studies that show that higher ribavirin dosages are associated with better odds of sSVR.
You said you were UND at week 12, but I'm guessing you weren't a rapid responder or UND at week 4?
I just don't see a problem with doing this. I am having to decrease from 1000mg by 200mg to 400mg per day (I'm trading off 800mg one day, 600mg the next) due to hemaglobing counts that keep going down between 7-8. I have a lot going for me. I was a rapid responder, I was UND at week 4 - but I am STILL nervous about having to go lower on my ribavirin)
This is just my opinion though. Other people with more experience and time in here may disagree.
new words folks: sSVR and hemaglobing
LOL geez... I totally can't spell anymore
Curious why you're treating for 48 weeks instead of the standard 24 for geno 3's? Is this your first time treating or have you treated before. If the latter, what happened and on what doses of meds -- non-response, relapse, etc? Any other negative pre-tx predictors such as fatty liver, overweight, afro american race
Forgot to ask if you tested viral load prior to week 12, and if so, what were the results.
I'm going to write a new hepc dictionary
the entire 12 weeks issue, I think, may be the reason her doctor wants to increase