Aa
A
A
A
Close
Hepatitis C Community
13.4k Members
Avatar universal

Rebetron Question

Can anyone tell me why Rebetron should not be used by men whose female partners are pregnant? Thanks!
20 Responses
Avatar universal
I understand that is on the prescribing instructions.

My take is that it may have to do as much with legal issues as practical. I imagine that if you make sure you're wife doesn't handle the ribavirin (Rebetron), and you wash your hands after touching it, and you use condoms, that the ribavirin shouldn't get transferred to your wife. Should it get transferred to your wife, it could harm the fetus.

That said, none of us are doctors or pharmacists here, so you should really ask your doctor and/or pharmacist the same question before making any decisions. Also, the drug companies have free help lines with nurses available, and you might try them as well.

Good luck!

-- Jim
Avatar universal
Because the drugs are known to cause birth defects. Here is the warning for the drug, your drug bottle should have a warning label also.

CONTRAINDICATIONS AND WARNINGS
Combination REBETOL/INTRON A therapy is contraindicated in women who are pregnant and in the male partners of women who are pregnant. Extreme care must be taken to avoid pregnancy during therapy and for 6 months after completion of treatment in female patients, and in female partners of male patients who are taking combination REBETOL/INTRON A therapy. Women of childbearing potential and men must use two reliable forms of effective contraception during treatment and during the 6-month posttreatment follow-up period. Significant teratogenic and/or embryocidal effects have been demonstrated for ribavirin in all animal species studied.
Avatar universal
Thanks!
Avatar universal
You might want to wade through this with particular attention to Dr. Eugene Schiff's answer to a similar question. Dr. Schiff is one of this country's leading hepatologists. If this becomes an issue with your treatment doctor, you -- or your doctor -- might want to contact Dr. Schiff for clarification.

http://hepatitis-central.com/hcv/hepatitis/symposium99/maddrey.html
96938 tn?1189803458
The same stuff has several names; ribavirin, rebetol, rebetron, copegus....and a few others that would turn into asterisks.
107513 tn?1232290064
You just gotta love that answer from Schiff....That Doc is one of a kind!!
Have an Answer?
Top Hepatitis Answerers
317787 tn?1473362051
DC
683231 tn?1467326617
Auburn, WA
Learn About Top Answerers
Didn't find the answer you were looking for?
Ask a question
Answer a few simple questions about your Hep C treatment journey.

Those who qualify may receive up to $100 for their time.
Explore More In Our Hep C Learning Center
image description
Learn about this treatable virus.
image description
Getting tested for this viral infection.
image description
3 key steps to getting on treatment.
image description
4 steps to getting on therapy.
image description
What you need to know about Hep C drugs.
image description
How the drugs might affect you.
image description
These tips may up your chances of a cure.
Popular Resources
A list of national and international resources and hotlines to help connect you to needed health and medical services.
Here’s how your baby’s growing in your body each week.
These common ADD/ADHD myths could already be hurting your child
This article will tell you more about strength training at home, giving you some options that require little to no equipment.
In You Can Prevent a Stroke, Dr. Joshua Yamamoto and Dr. Kristin Thomas help us understand what we can do to prevent a stroke.
Smoking substitute may not provide such a healthy swap, after all.