I think the metabolic stress HR refers to is partially associated with obesity, overeating, smoking, drinking etc, lack of exercise and consumption of sugar or things that result in elevated blood sugar. The usual suspects. I seem to remember him discussing that, but obviously he should be the one to clarify.
The search function on this site leaves a lot to be desired. But I found a few links where HR discussed antifibrotics, although in my cloudy tx addled memory banks I think he posted a "seminal work" on the matter that I couldn't find. If anyone else has it please post it. This is fabulous info, we should be grateful to have access to it...I mean where else are we gonna get this stuff?? HR you rock man, HUGELY DUDE! Thanks again...
So I google that long name:
"Polyunsaturated phosphatidylcholine" and got a ton of good links.
Only clicked on this one, and it is chock full of stuff. I guess that big word can be reduced to the word "choline":
I remember years ago, when most of you were no taller than your mommie's knee :-() Dirk Pearson talked about the only way to take choline was in liquid form because it deteriorated in air when in powder form. He application was for brain fuel and weight reduction but here is the stuff on the Life Extension Foundation website. (it used to be only Twin Labs had it, now they don't). It's really cheap.
Now, maybe I'm making big illogical jumps here, instead of big logical jumps. I could be way off and so tell me if I'm wrong:
PPC is choline is best taken as a liquid.
and. . . for those whose computers are broken, here is a couple extracts from thiis link:
• Choline is available as a soluble salt, most commonly as either choline bitartrate, citrate, or chloride, or as phosphatidylcholine in lecithin.
• Most commercial forms of lecithin contains only 10-20% phosphatidylcholine.
• Most supplements labeled as "phosphatidylcholine" contain only 35 percent.
• Some newer and more potent preparations contains up to 98 percent phosphatidylcholine. These more pure forms of phosphatidylcholine are preferred since they are associated with fewer gastrointestinal side effects. This is particularly true in the treatment of those conditions that require large doses of phosphatidylcholine (i.e., 15 to 30 grams) because low-concentration forms such as lecithin would be required in such large amounts that side effects would be nearly inevitable.
Intravenous form is also available. The liver is the largest organ of the body and receives the first flush of PC from an infusion. However an exchange of lipids is systemic with every organ, every neuron, every cell sharing the increased PC and the higher performing lipids (HUFAs). It should be expected that improved metabolic performance would also be systemic.
and last but not least:
Appendix: Food Sources of Choline
Choline and Choline Phospholipid Content of Selected Foods, in Milligrams per Serving Free
Food Serving Choline Lecithin Total Choline
Apple 1 medium 0.39 29.87 4.62
Banana medium 2.85 3.26 3.52
Beef liver 3.5 oz 60.64 3362.55 532.28
Beef steak 3.5 oz. 0.78 466.12 68.75
Butter 1 tsp. 0.02 6.80 1.18
Cauliflower 1/2 cup 6.79 107.06 22.15
Corn oil 1 tbsp. 0.004 0.13 0.03
Coffee 6 oz. 18.59 2.05 19.29
Cucumber 1/2 cup 1.18 3.06 1.74
Egg 1 large 0.22 2009.80 282.32
Ginger ale 12 oz. 0.07 1.11 0.34
Grape juice 6 oz. 8.99 2.11 9.37
Human milk 1 cup 2.10 27.08 10.29
Iceberg lettuce 1 oz. 8.53 2.86 9.06
Infant formula 1 oz. 0.818 2.97 1.38
Lecithin supplement 1 tbsp., 7.5 g. NA 1725 250
Milk whole 1 cup 3.81 27.91 9.64
Orange 1oz. 13.24 107.35 27.91
Potato 1 5.95 25.97 9.75
Tomato 1v 5.50 4.94 6.58
Whole wheat bread 1 slice 2.52 6.57 3.43
(USDA: Composition of Foods. USDA handbook # 8. Washington DC, ARS, USDA, 1976-1986)
No. its NOT just choline, very far from that. It is a polyunsaturated fatty acid attached to phosphatidyl-choline. I do not like to mention any brand names here, but this is too important to let it go into nowhere. Check the brand name hepatopro. This is exactly that PPC compound mentioned in the article above.
whoa! I just looked at the food sources of choline and coffee (that's C-O-F-F-E-E) has more choline than anything but beef liver (bleah).
Starbucks, here I come!
aha, thank you for setting me straight.
would it be safe to say that the choline in food would also have this fatty acid even though not an exact science?
Heading off to google "hepatopro"