Hepatitis C Community
13.4k Members
Avatar universal

Ribavirin rash?

I'm in the Telaprevir trial in week 13, so I finished the Telaprevir (or placebo) this past Wednesday.  A day or two before that my scalp started itching.  Yesterday it spread to the point that I had the itchies on almost half my body.  Then I noticed tiny bumps where it itched worst.  I took Benadryl, which didn't make it totally go away but brought it under control.  It's better today but not gone.  Just took another Benadryl.  The rashy areas are a little pinker than normal skin but not bright red.  Could this be the infamous "Ribavirin rash"?  Does it sound like it to folks who have had it?  If so, what did you do about it?  My Ribavirin dose was just reduced from 1000mg/day to 600mg/day.  Will that make the rash go away?  If so, how soon?  I see my doctor next Tuesday but figured I'd query the community now to see what wisdom can be offered by those with experience.

Thanks in advance...

9 Responses
476246 tn?1418874514
From what I've read so far, Telaprevir and Ribavirin both may produce rash and Telaprevir is supposed to be worse one of them.

Hope it will go away real fast.

Avatar universal
There are several members here that are in the Telaprevir trials or who have completed their treatment and am sure they will chime in to help answer your question. You may want to query Andiamo1 for he has completed his treatment with Telaprevir and has had a problem with the rash. I could say the sever rash, but have not treated with Telaprevir in the mix. Good Luck to you!

412873 tn?1329178055
I used a cortisone cream-desoximetasone 0.25%-this is allowed in the trial.  I only had to use it for a day or two.  And I take Atarax 10mg.  It is not as drying as benedryl.  

I hope you get some relief=)

Avatar universal
Sorry I have only been in the VX trial for a little more then a week so I can't really help. I asked the trial nurse about benadryl and she said it was not allowed in the trial. I then asked if I could take tylonol PM to sleep and she said no because that has benedryl in it. so I guess benedryl is not an option for us in the telaprevir study?
577132 tn?1314270126
First of all I was not a part of the trial you are talking about but I did experience the Riba rash (small, raised,  itchy, red dots) very early on in treatment.  There are several things I tried to help and these are the ones that I had success with:

1. Drinking enough water
2. Banishing all forms of Sodium Laurel Sulphate in my personal hygiene regime.  ie use organic shampoos and soap substitutes.  Read all labels carefully as you will find SLS, or SAS in products you could never imagine!
3. Using a 10% Urea cream all over my body and limbs twice a day to keep my skin hydrated.
4. Adding a tablespoon Virgin Coconut Oil to my breakfast and a teaspoon of Fish Oil (Omega 3 & 6) after breakfast.  This one is VERY effective, my itching has ceased since I added this in.
5. For the really really itchy ones back at the beginning I also used a Hydrocortisone cream.

Hope this helps!

Epi :)
Avatar universal
Being you are finished with the study drug it is probably the riba rash. Stay out of the sun completely, don't shower too often, oatmeal baths, and ice packs to take away the redness. I find cold air eases the itch.
Good Luck!
Have an Answer?
Top Hepatitis Answerers
317787 tn?1473362051
683231 tn?1467326617
Auburn, WA
Learn About Top Answerers
Didn't find the answer you were looking for?
Ask a question
Answer a few simple questions about your Hep C treatment journey.

Those who qualify may receive up to $100 for their time.
Explore More In Our Hep C Learning Center
image description
Learn about this treatable virus.
image description
Getting tested for this viral infection.
image description
3 key steps to getting on treatment.
image description
4 steps to getting on therapy.
image description
What you need to know about Hep C drugs.
image description
How the drugs might affect you.
image description
These tips may up your chances of a cure.
Popular Resources
A list of national and international resources and hotlines to help connect you to needed health and medical services.
Here’s how your baby’s growing in your body each week.
These common ADD/ADHD myths could already be hurting your child
This article will tell you more about strength training at home, giving you some options that require little to no equipment.
In You Can Prevent a Stroke, Dr. Joshua Yamamoto and Dr. Kristin Thomas help us understand what we can do to prevent a stroke.
Smoking substitute may not provide such a healthy swap, after all.