Aa
Aa
A
A
A
Close
Avatar universal

EOT undetected but High Ceruloplasmin and low platelets??

4 weeks after my 48 week triple therapy EOT I am still undetected, but I'm concerned about some of the other numbers in the results. While my liver enzymes have come down they're still higher than range with ALT @ 81 (0-44) and AST @ 62 (0-40), also two other concerns. Anybody have values still out of whack 4 weeks beyond EOT like this?

Platelets are at 63, but it says may be higher due to clumping

Ceruloplasmin is high at 79.6 with normal range being 15.0 to 30.0 mg/dl

Thanks
3 Responses
Sort by: Helpful Oldest Newest
317787 tn?1473358451
Hi, Hector has given you excellent advice.  I just wanted to add it took my levels a while to normalize after I finished tx..  I am sure yours will normalize as well.  
I am sorry to say I don't know anything about the ceruloplasmin.
Helpful - 0
Avatar universal
I'm seeing a hepatologist out of Eienstien Hospital in Philly. Based on my elevated liver enzymes which were alt 133 and ast 100 and now are still out of range but lower at alt 81 ast 62 four weeks EOT, and my platelet count I think he may suspect some autoimmune activity. So he ran a battery of tests which included the Ceruloplasmin.  I just got the results today
Helpful - 0
446474 tn?1446347682
What was your platelet count before starting treatment? Hep C treatment that is interferon based always lowers platelet count so is to be expected. It takes time for platelet count to rise after treatment.

What stage of liver disease did you have before starting treatment?

Why are you being tested for Ceruloplasmin? Do you have a problem with copper levels? Ceruloplasmin is not a routine test. Unless your doctor suspects Wilson disease or a problem with copper metabolism, it is unlikely that anyone will ever have this test performed.

Ceruloplasmin is normally only ordered along with blood and/or urine copper tests to help diagnose Wilson disease. Wilson disease is commonly found in young people an is a serious life-threatening liver disease that is an inherited disorder associated with DECREASED levels of ceruloplasmin (below 10 mg/dL) and excess storage of copper in the liver, brain, and other organs. Rarely, it may be ordered to help diagnose or differentiate between conditions associated with copper deficiencies.

Ceruloplasmin is frequently ELEVATED when someone has inflammation, severe infection, tissue damage, and may be increased with some cancers.
Are you seeing a gastroenterologist who specializes in liver disease or a hepatologist who knows about copper related liver disease.

Good luck.
Hector
Helpful - 0
Have an Answer?

You are reading content posted in the Hepatitis C Community

Top Hepatitis Answerers
317787 tn?1473358451
DC
683231 tn?1467323017
Auburn, WA
Learn About Top Answerers
Didn't find the answer you were looking for?
Ask a question
Answer a few simple questions about your Hep C treatment journey.

Those who qualify may receive up to $100 for their time.
Explore More In Our Hep C Learning Center
image description
Learn about this treatable virus.
image description
Getting tested for this viral infection.
image description
3 key steps to getting on treatment.
image description
4 steps to getting on therapy.
image description
What you need to know about Hep C drugs.
image description
How the drugs might affect you.
image description
These tips may up your chances of a cure.
Popular Resources
A list of national and international resources and hotlines to help connect you to needed health and medical services.
Herpes sores blister, then burst, scab and heal.
Herpes spreads by oral, vaginal and anal sex.
STIs are the most common cause of genital sores.
Condoms are the most effective way to prevent HIV and STDs.
PrEP is used by people with high risk to prevent HIV infection.