Hepatitis C Community
13.4k Members
Avatar universal


Looking for some collective wisdom here.

As you probably know if you've been reading my posts, one of my worst side effects on treatment is reflux. The traditional medicines (PPI's, H2's, Antacids) are only helping marginally. Same with diet changes (lived on rice gruel and boiled chicken for a month. UGGGH! and still only a little relief)

A few days ago I decided to approach the problem differently. Like many, the riba puts me under a lot of physical and mental stress. When I'm alone (most of the time these days LOL) it's really not so bad. But most real life interactions are magnified. If I'm talking on the phone with a friend or relative that I don't quite get along with, things are like 100 per cent worse than they used to be pre-treatment.)

Anyway, my new approach is to try to reduce my stress level which hopefully will help reduce the reflux. This is not a novel approach as many have linked stress and reflux.

After trying meditation, Alexander technique, breathing exercises, massage, etc, I've come to the conclusion that for now MS Riba is stronger mistress than I can handle on my own. So...I've turned to some drugs for help.


(ran o
28 Responses
Avatar universal

A couple of days ago I started taking Xanax and noticed some improvement not only in my stress levels but with the reflux.

Besides being a little groggy -- hopefully temporary -- I'm concerned about getting addicted to the drugs, as I'm pretty sensitive to most drugs. Even this morning -- day three on Xanax -- I felt a bit more anxious than normal until I took the drug. (Actually this morning I took some valium (same class of drug) to see how that might work.

So first, I'm looking for any of your experiences with Xanax, Valium, etc. And second, I'm looking for alternatives that may not be as addicting.

The first thing that comes into my mind are SSRI's like Prozac or LexiPro. Thing is I'm not depressed, but if these drugs would "chil me out" enough to help the reflux, maybe they're worth a try. My understanding is they're not additive.

Any comments, suggestions, welcome.

G r o g g y  but refluxing a little less...


Avatar universal
Hi Jim;
      I take Klonopin. It is a med that is used to treat seizures and anxiety. My doctor originally gave me small doeses to help with insomnia. It does help me sleep.

But, when I hit my 4th month, I began getting Riba rage & very stressed about little things. As you said, not depressed, but I felt really edgy and anxious for nothing. ( not like me at all, I have always been very chill, go with the flow ) I knew it was the tx.

So, since I was already taking small doses for the insomnia, my nurse upped my dose of Klonopin and it seems to be helping. Not only helping with anxiety & that edgy feeling, but taken before bed it really helps me sleep well.

Yes, it addictive, but arent'they all? It's one trade off for another. I like having my sleep & having more patience with all my children.

(((((( Sue ))))))
Avatar universal
Hi its me whoaisme, writing on Giddyup's computer...the first thing to remember "t is the meds taking over!!!"that riba is some strong stuff..so yes taking anti anxiety/anti depression/anti whatever it takes to get through treatment has been our approach! Giddy finishes his 48 weeks of daily infergen/riba in two weeks!! He is or has been on it all, right now his regimen is protonix for that churned up stomach feeling, compazine for the naseau, and lexapro for the "depression". We were told that valium is not liver friendly. He also takes ambien to sleep and when he truly needs it ativan for the anxiety. The ativan has a side effect of helping with the stomach problems, however I caution you that it is very addictive. So much for my collective wisdom! Good luck! Feel well! Su
Avatar universal
I was half crazy and I wouldn't call it depression.  I thought about a divorce from 25 years ago day and night.  I was furious at everybody I work with.  It took a toll on my wife but she gave me good support while it was going on.  The dr wanted me to start an antidepressant at the beginning but I told him I didn't think I'd need it.  At about 3 months I started welbutrin and buspar.  I can't really say if it did any good but at least I got all the way through tx.  The psychiatric symptoms were what nearly drove me off the tx.  I put up with the anemia, aches and the rest of the sx okay.  If I had to do it again, I'd start an antidepressant as soon as I knew I was going to start tx.  BTW my dr said that it's the inf that makes you crazy not the riba.  When I was thinking of quitting he said that I should try an inf dose reduction but I kept up the normal dose.  I had already had a 4 month riba reduction because of anemia.

I'm alcoholic.  I stopped drinking 35 years ago.  So sedatives aren't an option for me.  I don't remember seeing anybody here say the used them to counter sx but I really don't know.
Avatar universal
i was being treated for depression even before tx....the doctor had me switch from wellbutrin to zoloft (wellbutrin is not liver friendly).  I take zoloft daily which helps 85%with depression; and i also take klonopin for anxiety/nerves.  I don't care what tom cruise says - i've tried everything natural to deal with depression NOTHING has helped but medication...
everything was kind of changed to go with my new tx...i still get sad; but i don't want to not feel at all....it seems to be working for me...
good luck
and be well...
<3 michelle
Avatar universal
The only thing I would like to add is to never take Valium and Xanax together.  It can make you very sick.  If taking the Xanax makes you feel better while on treatment then take it.  Your Doc will cut you down slowly when it is time to stop (Usually over 4-6 weeks)so you won't feel too badly.
Just no Xanax and Valium together.  Wait at least 12 hours (or more) before switching from one to the other, and stay with that one. Using both from day to day is not good.
Feel better  :-)
Have an Answer?
Top Hepatitis Answerers
317787 tn?1473362051
683231 tn?1467326617
Auburn, WA
Learn About Top Answerers
Didn't find the answer you were looking for?
Ask a question
Answer a few simple questions about your Hep C treatment journey.

Those who qualify may receive up to $100 for their time.
Explore More In Our Hep C Learning Center
image description
Learn about this treatable virus.
image description
Getting tested for this viral infection.
image description
3 key steps to getting on treatment.
image description
4 steps to getting on therapy.
image description
What you need to know about Hep C drugs.
image description
How the drugs might affect you.
image description
These tips may up your chances of a cure.
Popular Resources
A list of national and international resources and hotlines to help connect you to needed health and medical services.
Here’s how your baby’s growing in your body each week.
These common ADD/ADHD myths could already be hurting your child
This article will tell you more about strength training at home, giving you some options that require little to no equipment.
In You Can Prevent a Stroke, Dr. Joshua Yamamoto and Dr. Kristin Thomas help us understand what we can do to prevent a stroke.
Smoking substitute may not provide such a healthy swap, after all.