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Sovaldi/Olysio Side Effect

I took my first dose of Sovaldi/Olysio this morning with breakfast. That was about 8 hours ago. The only thing I've noticed is a "tightness" in my head, it's not severe but I was a bit concerned. Anyone else experienced this while on the treatment? Feeling so blessed that Medicare Part D approved the drugs.
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Avatar universal
I went through the agony of the injections and pills in 2002-03 for 18 months. I was hospitalized a few times from the side effects, twice with pneumonia and once for 6 ½ weeks with acute pancreatis. It reactivated in 2007, Medicare denied treatment.  In 8 years it of coarse advanced to cirrhosis. Just yesterday I started treatment with Olysio and Sovaldi.  I feel Blessed that treatment is now an option, even with cirrhosis,  instead of waiting on a transplant. GOOD LUCK TO ALL. 

Helpful - 0
10875325 tn?1413496591
I just started the Sovaldi/Olysio treatment yestday. I've been through a lot. Tried treatments in 1999 and again in 2011. Had a transplant this past July. I want to kill this dragon once and for all!
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10875325 tn?1413496591
I just started my Sovaldi/Olysio yesterday. I am praying that I have a good outcome as well. I have been through a lot. Tried treatment in 1999 and again in 2011. Had a transplant this past July. So am hoping that this new treatment will kill this dragon once and for all.
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Avatar universal
I was told the same thing. I am in St. Augustine, so you know where I am, a major liver transplant center. I am hopeful and pray for us all.
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Avatar universal
I went through the oly/sov treatment and the only thing I would be concerned about is the fact that oly is a protease inhibitor, Incievek Lite so to speak. Since treating I've had some chronic pain issues that get better if I really watch my diet and fluid intake. I'm going to get and ultrasound done in two weeks to see if my liver has started to decompensate.

As I've said before I felt it stressed the liver during treatment so if I were in your shoes I would wait two or three months for the treatment that has been tested on more patients, is made by the same company and are in the same class of drug. Like everyone, you want the cure but to trade it for RA symptoms for the rest of your life when you could have just waited a few months IMHO is just not worth the risk. These are still very powerful drugs. Wish you all the best in whatever you decide to do.
Helpful - 0
Avatar universal
I am 65, very similar to you, I was stable and not many symptoms, good blood tests etc. I did the treatment, it was very easy, only 12 weeks and now I'm virus free. I did it for my future, because someday the virus would have taken it's toll and even if it was minimal, damage to the liver was being done. It is SO worth it, not ever having to worry about it again, very freeing. Good luck and I hope this helps you in your decision making!
Susie
Helpful - 0
Avatar universal
I am 60 years old and have had hep c geno 1a for about 36 years (they didnt recognize it until 2000. No change at all, Feel great no symptoms at all.Doc has been watching it since then with yearly bloodtests, very mild only slightly elevated enzymes, sometimes even normal. Doc says I am a lucky one & have a very healthy lifestyle. He is suggesting this new oly & soval regimin.Should I do it, it is so hard to do it when I feel great and I hate to take ANY drugs much less this major combo. Will I wake up a sleeping giant or do I wait longer..Im scared and just not sure..any thoughts
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Avatar universal
I was wondering when you take the meds? Do you take them together and in the evening? The nurse I talked too said this is the best but I wanted to ask my fellow brothers and sisters in this forum what was best for them? Also what about vit D and C and CoQ10? Should I stop them during treatment? I know you are not doctors, but I know you have been down the road and have great feedback.
Helpful - 0
Avatar universal
I have stage four cirrhosis and have recently started the Olysio and Sovaldi combination. According to my doctor, once the virus is gone, and no longer damaging my liver, there is a good chance my liver may begin to remodel itself. Do be hopeful and trust God.
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Avatar universal
I am so grateful that this combo became available. Thank You researchers and Hep C population for moving forward. Only 5 days in, sure beats tx of 13 years ago. Nonresponder then. Odds so much better. Happy to be alive to take this combo. Good thoughts to you all!
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Avatar universal
At the 3 wk mark w S/O and in fact see my GI guy tommorow to get the order for wk 4 bloodwork. Brain foggy for sure and tired. Itchy back but I had that prior so who knows.Lots[80+oz/daily]of water,eat before taking,avoiding sun and staying positive.Very grateful.
Helpful - 0
7510956 tn?1411671417
Congrats, I will be starting soon. What do you mean by little foggy?
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Avatar universal
Just stared solvaldi /Olysio  12 week treatment 7/31 /14  feeling blessed. Little foggy and skin irritation but so dar ok. Tried interferon treatment 10 years ago but didn't work for me. Good luck to all and I will share my progress
Helpful - 0
Avatar universal
Hello everyone.. I've had Hep C for 30 yrs. Got hit be a drunk driver and had to have a blood transfusion, and that was before they tested for Hep C. Anyway, years ago I tried the Peginterferon & Ribiviran tx and it pretty much wiped me out. After being hospitalized the 2nd time, my dr. discontiued the tx. and told me that in a few yrs there would be sumthing new coming out that would probably be more tolerable. Well the new treatment is out and I am on week 2 of Sovaldi/Olysio/Ribiviran tx. the 1st week was amazing. No side effects. Week 2, well, my drugs and body is at constant war. Itching, nausea, frequent bowel movements, fever, fatigue, irratibility are some of my side effects. But as God is my witness, I am going to finish this round of tx. This disease has run my life for over 30 years and its time to put it to stop..
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Avatar universal
sustained viral response or having no detectable virus in the blood 6 months post-treatment, which is considered a cure
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Avatar universal
So sorry to hear this, I hope this works for you and you get your transplant, etc...They are performing miracles now! Best of luck to you and hugs!!!!
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Avatar universal
My husband just started the Sovaldi/Olysis today.    I have been reading the posts, what does SVR stand for?  
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1774051 tn?1402002503
I was diagnosed end stage in 07 with cirrhosis and now have HCC (Liver cancer) Dr going to treat and start treatment if it works then eventually transplant so yes they can treat. That way you will be virus free if you have to have transplant in future.
Helpful - 0
1774051 tn?1402002503
In March it was confirmed Hepatocellur Carcinoma Dr. going to treat and start the new HepC treatment as my Medicare will pay. I currently am seeing a transplant Dr at the OU medical center in OKC,OK. Have you gone through this and I was a non-responder to the interferon & ribavirin. Went through all the side effects. I'm also a genotype3. He says my numbers are good. I've been on morphine for a year. My liver is cirrhotic.
Helpful - 0
Avatar universal
Treatment naive means you have never before taken any Hep C treatments. I also was treatment naive prior to the Sovaldi/Olysio combo. The cure is being virus free and sustaining that for 3 to 6 months post treatment. There's an over 90% cure rate happening with this combo. Don't delay any longer than necessary and best of luck to your husband!
Helpful - 0
Avatar universal
Hey,

I changed from taking my Sovaldi in the AM to PM because I felt that it was causing my brain fog issues and that seemed to help. That said, the brain fog issues may have cleared as my body got used to taking the Sovaldi/Riba (I am day 11 - 73 more days to go)!!!

Jo

Helpful - 0
8894163 tn?1401226192
sorry got cut off...cuz we're from Canada and he is hoping by October to have either 1 something covered by way of $ or some results from people whom have taken this drug with cirrhosis?
What does treatment naiive mean anyone?

Does anyone know of anyone whom already has cirrhosis along with their hep c and is taking the cure? And if so what is the cure comprised of?

Thank you
Helpful - 0
8894163 tn?1401226192
here here! Im with you on that! Can't wait until my husband can finally start! I don't know what the hold up is but out heptalogist said wait til October.....? He has cirrhosis/hep c now....I am kinda gettin' worried! Maybe cuz were fro
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Avatar universal
I have finished treatment for some time now.I am UND and get m final VL taken in July. I feel great.
Something I did was take the Solvadi at night.
Helpful - 0
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