Aa
The Waiting Game
http://pubs.acs.org/cen/coverstory/88/8818cover.html
Researchers expect three waves of small-molecule drug approvals, each of which will improve HCV treatment. First, telaprevir and boceprevir are likely to be approved next year as add-ons to the current treatment regimen. The second wave, in three to five years, will bring second-generation protease blockers, a crop of polymerase inhibitors, and new classes of compounds such as Bristol-Myers Squibb’s NS5A inhibitor and Debiopharm’s cyclophilin inhibitor. Finally, researchers hope that in the next five to 10 years they will reach the ultimate goal—enough data to convince doctors and the Food & Drug Administration that the virus can be quieted with combinations of small molecules alone.
Researchers expect three waves of small-molecule drug approvals, each of which will improve HCV treatment. First, telaprevir and boceprevir are likely to be approved next year as add-ons to the current treatment regimen. The second wave, in three to five years, will bring second-generation protease blockers, a crop of polymerase inhibitors, and new classes of compounds such as Bristol-Myers Squibb’s NS5A inhibitor and Debiopharm’s cyclophilin inhibitor. Finally, researchers hope that in the next five to 10 years they will reach the ultimate goal—enough data to convince doctors and the Food & Drug Administration that the virus can be quieted with combinations of small molecules alone.
Excellent article and very comprehensive on what we can expect for developments in treatment drugs over the next years. Thanks for posting this, Cory.
thanks! very nice up to date summary. This is the trade mag. for the American Chemical Society so their coverage is fairly detailed.
Have an Answer?
You are reading content posted in the Hepatitis C Community
Learn about this treatable virus.
Getting tested for this viral infection.
3 key steps to getting on treatment.
4 steps to getting on therapy.
What you need to know about Hep C drugs.
How the drugs might affect you.
These tips may up your chances of a cure.
A list of national and international resources and hotlines to help connect you to needed health and medical services.
Herpes sores blister, then burst, scab and heal.
Herpes spreads by oral, vaginal and anal sex.
STIs are the most common cause of genital sores.
Condoms are the most effective way to prevent HIV and STDs.
PrEP is used by people with high risk to prevent HIV infection.
