Well I agree treatment should not of been stopped as 48 weeks is whats called for if not und at week 4, missing only 3 doses should not be a huge deal... If you still have the riba and interferon I would get back on it and get into a hepa asap......... Good luck
First I would request a retest then go from there, if indeed he is detectable even <43 IU/ml he is technically detectable and the doc is following proper protocol stopping all treatment
2.3 Discontinuation of Dosing
Patients with inadequate viral response are unlikely to achieve SVR, and may develop treatment-emergent resistance substitutions [see Microbiology (12.4)]. Discontinuation of therapy is recommended in all patients with (1) HCV-RNA levels of greater than 1000 IU/mL at Treatment Week 4 or 12; or (2) confirmed detectable HCV-RNA levels at Treatment Week 24 (see Table 2).
Table 2: Treatment Futility Rules: All Patients
HCV RNA - Week 24: Detectable
Action - Discontinue peginterferon alfa and ribavirin
Ribavirin monotherapy is not effective for the treatment of chronic hepatitis C virus infection and should not be used alone for this indication.
Opps, keith is right, I was thinking not und at week 4 and you wrote week 24.
Welcome to the forum.
I am very sorry that your husband is still Detectable at week 24. I know it must be devastating to have to stop treatment.
However, if I was you, I would request another VL test to be certain there was no lab error and I would continue treatment until the results of that lab test are known (with your doctor's knowledge and okay, of course).
You do not state what happened the last time your husband treated. Did he ever clear the virus? Did he Relapse? Or did he not respond well (either a non-responder or a partial responder? His response to his last treatment would be a factor in determining how long he treated. If he relapsed, he would treat for 24 weeks. If he was a partial responder or a non-responder then he would do 48 weeks. Also, if he has cirrhosis he would do 48 weeks.
Also, was he ever Undetectable while on this 24 week treatment?
As far as viral load goes, he is either Detectable or Undetectable. There is no "technically undetected" status. If his VL showed 1000 IU/mL at Wk 4 or 12: stop all 3 drugs
2. HCV RNA detectable at Wk 24: stop all treatment
I guess it was the undetectable but detectable thing that threw me and then when this research person questioned it, it just had me a little frantic. Thanks for the input!