Aa
Aa
A
A
A
Close
2135877 tn?1381861126

UNDETECTABLE!

I'm on the Sofosbuvir/GS-5885/Ribaviran study for 12 weeks.  My one week viral load test just came back today ~~ undetectable!
14 Responses
Sort by: Helpful Oldest Newest
2135877 tn?1381861126
VERY GOOD SIGN!  

Not perfect...but definitely on the right track!

Oh, and some labs interchange 25.  I'm no expert, but I've never seen that before.
Helpful - 0
1480242 tn?1359201304
week 2  
Viral Load >25
Enzymes all WNL

cautiously optimistic.....
Helpful - 0
1840891 tn?1431547793
Eki, I'm so happy to hear your great news, wow, UND in one week! Congratulations! That's amazing, and also really nice to know just in case I'm not SVR. I have just a few more weeks before that critical 24 weeks post-EOT test. It will probably be good, but I can't let myself count on it yet, not after all my previous failures. Do continue to give us news of how it's going.
Helpful - 0
3140551 tn?1343251437
Beautiful news!  Every victory is cause for celebration for all of us!!!  
Helpful - 0
1480242 tn?1359201304
Thanks Eki1
I should be getting my two week kabs thrusday.
Then i dont get tested again till week 4
On IFN my numbers doubled in 3 months!
I havent seen mormal enzemes till last week either
You are right on, Undectable is the only number that coundts!
Again, thank yo for taking the time to explain. i really appreciate it
I havent allowed myself to get too worked up ovre it
  I'm cautiously optimistic.


Mike
Helpful - 0
2135877 tn?1381861126
Hi Mike,

Well, you're looking at a logarithmic drop, not really a straight number drop.  Yes, I'd say that your numbers are good for one week.  You have more than a 4 log drop, so that's very good.

Your next test result, and the one after at four weeks will be very interesting.  The virus replicates very quickly...and it doesn't check itself to see if it has a perfect copy.  That means that it gets all sorts of defective replicas, but every once in awhile it gets lucky and replicates one that's resistant to your meds.

At least, that's how my GI/Hepatologist explained it to me.

Ike
Helpful - 0
1480242 tn?1359201304
'm not in the Gilead trial, (congrats to all doing well with it)
was just trying to get some thoughts on viral loads,. I don't know if my numbers are good or not
I'm in another study, but thats irrelevent.
When I was screened my Vl was 8.9 million
After one week it was 200.

Would one of guys more experienced with this stuff care to give me their thoughts on this number. Is this good?

All my enzemes returned to normal for the first time since being diagnosed  in 1996 too,

exercise fatigue and brain fog (min.)

Thanks so much

GT 1A Cirrhotic CT. failed IFN/RIBO prior

Mike


Helpful - 0
3122657 tn?1357432602
Its always nice to see an undetectable post it is a real good feeling when you get that news good luck with the rest of your treatment

Best of luck to you
Helpful - 0
446474 tn?1446347682
Nice job! You are on your way. Remember to take all doses and you have a great chance of SVR.

Sofosbuvir works like a charm doesn't it.

I'm a previous genotype 1b null-responder with cirrhosis to peg-INF + Ribavirin

'An Open-Label Study to Explore the Clinical Efficacy of GS 7977 With Ribavirin Administered Pre-Transplant in Preventing Hepatitis C Virus (HCV) Recurrence Post-Transplant'
Conditions: Hepatitis C;   Hepatocellular Carcinoma
Intervention: Drug: GS-7977+RBV

Had a viral load of 692,000 day 1
One week - 581
Two week - <25 UND     4.44 log drop
I am now on week 24 of treatment.

Cheers!
Hector
Helpful - 0
Avatar universal
Glad to hear.  I got the same news last week from week 2 labs.   Hang in there this is good news.
Helpful - 0
Avatar universal
WOW...one week!!!! Unbelievable. I'm in week 13. UD @ week 2. Had my 12 week UD report yesterday :-)

You must be over the moon!!!!
Helpful - 0
Avatar universal
Congrats. I am on the same study and went UND at week 4. My 1st and 2nd week blood draw were <25. No 3rd week draw. 4th week draw UND. First time I have achieved UND  in 4 treatment attempts.
Helpful - 0
1815939 tn?1377991799
This is wonderful news, Eki, and I am hoping this time you will attain SVR. Sending positive thoughts and energy and wishes your way.   : )
Helpful - 0
2135877 tn?1381861126
Oh, and I failed triple therapy last spring.  I want to thank this group for all the great information, support, and help.  THANKS SO MUCH!

There are about seven posters who are stellar, and I'm afraid to name them for fear of leaving one off....but I'm grateful for all the time and energy you put into making this a great community.
Helpful - 0
Have an Answer?

You are reading content posted in the Hepatitis C Community

Top Hepatitis Answerers
317787 tn?1473358451
DC
683231 tn?1467323017
Auburn, WA
Learn About Top Answerers
Didn't find the answer you were looking for?
Ask a question
Answer a few simple questions about your Hep C treatment journey.

Those who qualify may receive up to $100 for their time.
Explore More In Our Hep C Learning Center
image description
Learn about this treatable virus.
image description
Getting tested for this viral infection.
image description
3 key steps to getting on treatment.
image description
4 steps to getting on therapy.
image description
What you need to know about Hep C drugs.
image description
How the drugs might affect you.
image description
These tips may up your chances of a cure.
Popular Resources
A list of national and international resources and hotlines to help connect you to needed health and medical services.
Herpes sores blister, then burst, scab and heal.
Herpes spreads by oral, vaginal and anal sex.
STIs are the most common cause of genital sores.
Condoms are the most effective way to prevent HIV and STDs.
PrEP is used by people with high risk to prevent HIV infection.