Many of us were switched by our insurance companies from brandname Ribavarin to the generic at the beginning of the year. I think it just became widely available although it's been out there for at least 6 months. Anyway--opinions differ.I know some folks on the board fought hard to stay on the brand name stuff I switched to the generic and haven't noticed the difference--side effects still stink. I suppose the jury is still out, but lots of generics have been proven just as effective as the brandnames. When I was taking the Co-peg the 'list' price was about $1,300 a month. Now that I'm taking the generic the price has dropped to a 'mere' $600 a month. My co-pay stayed at $30 but I think if I had fought for the brand name, at best my co-pay would have gone up to 50% of the $600. I think I have a lot more to worry about re: treatment and Hep C then whether I get the generic or brand name drug but that's just my opinion. I remember Jim saying that 'he chose to leave the dance with the same lady he came in with' when they tried to switch him. So--there is another opinion. By the way Jim: if you are reading this, good luck to you--I know you are winding down and weaning yourself off the board, but when I first started treatment last Spring I learned so much from you--thank you.
Posting above to Illona reminded me of this study, which may bear reposting.
<i>The use of higher dose weight-based RBV (1,000-1,600 mg/d) with EPO at the start of HCV therapy significantly increased SVR in patients with HCV genotype 1:
-across all body weights
-in both whites and blacks
The increase in SVR was achieved:
-despite the need to dose reduce ribavirin in 31 percent of patients
-significant reduction in relapse occurred. </i>
<a href="http://www.natap.org/2005/AASLD/aasld_61.htm">From Here.</a>
In reading the report posted by goof....all I can say is duuhhhh.
I think the participants here, even in our less than lucid moments, could have come up with that hypothesis. In fact, I think we have the various test groups underway in the 'Medhelp Study' going on right now...Cohorts.
<i>In reading the report posted by goof....all I can say is duuhhhh.</i>
Glad to see those mental functions returning to full capacity ;-)
As I read that report, I interpret it to say that an extra riba pill a day can really improve odds for SVRs. There are a few of us here, but I think it's far from routine for folks to ask to start tx with higher than stardard riba. Woth a read for new patients, IMHO.
If I knew at the start of tx what I know now I probably would have been inclined to 1000, rather than 800 in the early week/months. I think that I would even subsribe to the pre-IFN riba build-up too. On the other hand, and this is not at all scientific, it seems like a whole lot of folks seem to cross the anemia line at 1000 and sooner or later hit that wall. Tough choices to be sure. Riba is just nasty.