aftermath of treatment

[barryd]

i have been off of meds for about 2 years(peg/riba) and was unable to beat the virus, since i have been off the meds i have been getting anxiety attack's,bursts of uncontrollable rage, my memory is just about gone and extremely short tempered, my wife says i have been going from bad to worse since stopping meds, my question: is this normal after going thru treatment ???? i was taking meds for 72 weeks. thank you

[mikesimon]

J Hepatol. 2008 Nov;49(5):831-44. Epub 2008 Aug 21.

Hepatitis C infection and risk of diabetes: a systematic review and meta-analysis.

White DL, Ratziu V, El-Serag HB.

Section of Gastroenterology and Hepatology, Baylor College of Medicine, Michael E. DeBakey VA Medical Center, Houston, TX 77030, USA.
Abstract

BACKGROUND/AIMS: Several studies found hepatitis C (HCV) increases risk of Type II diabetes mellitus (DM). However, others found no or only sub-group specific excess risk. We performed meta-analyses to examine whether HCV infection does increase DM risk in comparison to the general population and in other sub-groups with increased liver disease rates including with hepatitis B (HBV). METHODS: We followed standard guidelines for performance of meta-analyses. Two independent investigators identified eligible studies through structured keyword searches in relevant databases including PubMed. RESULTS: We identified 34 eligible studies. Pooled estimators indicated significant DM risk in HCV-infected cases in comparison to non-infected controls in both retrospective (OR(adjusted)=1.68, 95% CI 1.15-2.20) and prospective studies (HR(adjusted)=1.67, 95% CI 1.28-2.06). Excess risk was also observed in comparison to HBV-infected controls (OR(adjusted)=1.80, 95% CI 1.20-1.40) with suggestive excess observed in HCV+/HIV+ cases in comparison to HIV+ controls (OR(unadjusted)=1.82, 95% CI 1.27-2.38). CONCLUSIONS: Our finding of excess DM risk with HCV infection in comparison to non-infected controls is strengthened by consistency of results from both prospective and retrospective studies. The excess risk observed in comparison to HBV-infected controls suggests a potential direct viral role in promoting DM risk, but this needs to be further examined.

[neenokhan]

i feel weak 5 years after treatment and also become angry and anxious and forget easily besides now suffering from diabetes Has HCV anything to do with my being diabetes as it started when i got sick

[barryd]

thank you for the advise , i have an appointment with my Dr. monday maybe he can give me some thing that will help me out a little, but at this time i am taking nothing. as far as memory, if i dont write it down it will not get done, i was on the meds for 72 weeks, i cleared and then it came right back, still till this day its at a low level, but its still here, thank you again.i will post later what he says to do or give me....

[sfbaygirl]

My memory seems better after a year post tx. Also my rage after riba is much better too. Are you on a anti depressant?  I think that may help. It sounds like you need to see a psychiatrist who can prescribe something for these symtoms. I had anxiety attacks, years ago. I went to a hypnotist. I really helped, I have never had them again. I do get anxious at times, but nothing like I did before. Exercise is great. Also Vit. B.

[hippygem]

Hi Barry, I did the tx in 2004, suffer anxiety (which I have now stabilised by taking vitamins/supplements), my moods are terrible and can go into a rage as well.  Memory is real bad, cant remember what I did yesterday so to speak.  I feel I have lost control of my emotions and feelings.
My friend did the tx 7 years ago, and his memory issues are still a concern, he also cleared the virus.  I believe that the virus lives in the tissues/brain even if you clear the virus, which may also explain why we suffer 'brain fog'. These symptoms are also experience by people with HCV who have not had treatment.  See study by Daniel Forton et al 2001 - Evidence for a cerebral effect for the hepatitis C virus. (Lancet, Vol 358. pp38-39).