the Kupfer cells, which are sitting there to catch these foreign intrusions that all hit the liver first.
It is therefore, together with some probiotic bacteria, part of any reasonable probiotic/eubiotic treatment plan of the intestinal flora, with great importance to anyone with liver disease and and eye towards reducing hepatic and systemic inflammation, fibrosis progression /regression.
It is something that, in low dose, even a "healthy" person should consider as part of his/her lifestyle.
Here is a study to determine its "toxicity":
Lactulose has profound health benefits by way of increasing bifidobacterial flora in the intestine of infants thereby protecting them against enteric infection, constipation and systemic encephalopathy. In the present study to assess the sub chronic toxicity of lactulose syrup, the rats were fed on a basal feed supplemented with lactulose syrup at 0.5, 1.0, 2.0 and 5.0% for a period of 21 weeks. Monitoring of food consumption, gain in body weight and physical observations did not reveal any treatment-related toxicity in any of the group of rats. Terminal autopsy also did not reveal any signs of toxicity. Further, no significant alterations in relative organ weight, serum biochemistry and urinalysis were observed up to 1% lactulose supplementation level. The results suggest that supplementation of lactulose in the diet does not produce any toxicity at the doses tested.
Supplements as of 1/1/08 I have added links if additional info wanted.
a multi vitamin/no iron
1000 mg of Salmon Oil (epa=160 mg / dha=240 mg / omega 3 = 400 mg) x1
1000 mg of Flaxseed Oil (ALA/omega 3 450 mg / omega 9 110 mg) x1
Raw flaxseed/ 1 teaspoon daily
Hepatapro PPC (polyunsaturated phosphatidylcholine 900 mg) x 2
Resveratrol (500 mg) x1 and x2 (alternate every other day) info: http://www.lef.org/resveratrol/ source: http://megaresveratrol.com/
NAC--(n-acetyl-l-cysteine) A sulfur compound that is a precursor of glutathione and protected sulfur-containing amino acid (600 mg) x2 with Vit C (500 mg) x2 Info: http://tinyurl.com/9yopf
TMG (trimethylglycine) (750 mg) x 2
Taurine (500 mg) x 2
Life Extension Super Curcumin W/Bioperine 800Mg 60 Caps (800 mg) x 2 / Powerful Antioxidant Properties to scavenge free radicals Anti-Inflammatory Actions Enhances important detoxification enzymes Curcumin increases the secretion of bile by stimulating the bile duct. It also protects the liver by detoxification, stimulating the gall bladder and scavenging free radicals. With the help of the adrenal glands, it inhibits both platelet aggregation and the enzymes which induce inflammatory prostaglandins. Curcumin may also help break down fats and reduce cholesterol. Large doses not recommended in cases of acute bilious colic, obstructive jaundice, painful gallstones, and extremely toxic liver disorders
Sylmarin (360 mg) x 3 / Milk thistle provides hepatocellular protection by stabilizing hepatic cell membranes.
Green Tea Extract (300 mg) x 2
/ info: http://tinyurl.com/ypdp9q
Coq10 (200 mg) x 1
info / http://tinyurl.com/29em8c