antibiotics while on treatment

[uncledudeness]

i am in my second week of triple with inc, and i think i have some kind of ear/gland/throat thing goin on. i am getting a dull throbbing pain on the right side of my head, with a really bad sinus headache. i've been taking sudafed and tylenol but it's not helping. so the questions is can you take antibiotics while in treatment? i have no allergies to antibiotics. i go for my 2 week labs this friday and i have an appointment with my NP next friday.....sidenote: i feel like i have an infection.

[sadmommyjoy]

Are your labs always every two weeks?

[PJ1966]

I had a bladder infection after 1 wk of starting triple therapy.  I couldn't believe it.  But the antibiotics worked and so far so good.  I was undetected at week 3 so it didn't seem to have any impact.  I'm in week 5 now.  Can't wait till week 12!

[uncledudeness]

thanks for your responses. i have an appointment with my DR on wed to discuss it further. i don't think i want to take anymore meds unless it's essential.

i think it's just the sides messin me up. gotta deal with it.

[working dog]

i had ear and throat problems throughout tx...as well as almost constant ringing in my left ear...the good thing is post incivek that sx was much easier to handle...the incivek made me feel like i was hit on the side of my head and was a recovering boxer...not fun stuff ..

[Gerbils]

Hi,
I had similar issues during tx with Incivek and working with my GP and gastro was given amoxicillin. I am currently SVR so it all worked. As usual the gang (Hector, OH, and Dee) have given you great advice. Talk to your docs and best of luck on your journey!
Gerbils

[Dee1956]

Hi just wanted to say I am sorry you are feeling bad. Hawk and Hector have given great advice.
I just wanted to say, I hope you feel better soon
Dee

[HectorSF]

If you look at the Incivek label
http://pi.vrtx.com/files/uspi_telaprevir.pdf

you will see the following...

Table 5: Established and Other Potentially Significant Drug Interactions: Alterations in Dose or Regimen May Be Recommended Based on Drug Interaction Studies or Predicted Interaction [See Clinical Pharmacology (12.3) (Tables 6 and 7) for Magnitude of Interaction.]

ANTIBACTERIALS

clarithromycin
erythromycin
telithromycin

Effect on concentration of INCIVEK or Concomitant Drug
↑ telaprevir  
↑ antibacterials

Concentrations of both telaprevir and the antibacterial may be increased during co-administration. Caution is warranted and clinical monitoring is recommended when co-administered with telaprevir. QT interval
prolongation and Torsade de Pointes have been reported with clarithromycin and erythromycin. QT interval prolongation has been reported with telithromycin.

I would talk with your gastro or hepatologist about what is the most appropriate drug for your condition that doesn't interact with Incivek.

So you feel so bad.
Good luck to you!
Hector

[orphanedhawk]

You can but you should be running everything by your hepatologist, or GI or whoever is doing your treatment. Call them and ask. Don't wait for next week.