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can i take harvoni if i have aschites and decompensated cirosis ?

can i take harvoni if i have aschites and decompensated cirosis ?
5 Responses
6708370 tn?1471490210
yes

http://www.hcvguidelines.org
Avatar universal
Read the hcvguidelines There are situations where Harvoni can be used. But As mentioned only a medical professional perferably in a liver transport center should provide you with an answer after asscessing your current condition.

Best wishes for obtaining a successful outcome.

http://www.hcvguidelines.org/full-report/unique-patient-populations-patients-decompensated-cirrhosis

Accessed December 16, 2015

Patients with HCV genotype 1 or 4 infection with decompensated cirrhosis (moderate or severe hepatic impairment; Child Turcotte Pugh [CTP] class B or C) should be referred to a medical practitioner with expertise in that condition (ideally in a liver transplant center).
Rating: Class I, Level C

Recommended regimens for patients with genotype 1 or 4 HCV infection with decompensated cirrhosis (moderate or severe hepatic impairment; CTP class B or C) who may or may not be candidates for liver transplantation, including those with hepatocellular carcinoma.
Daily daclatasvir (60 mg), sofosbuvir (400 mg), and low initial dose of RBV (600 mg, increased as tolerated) for 12 weeks is recommended for patients with HCV genotype 1 or 4 with decompensated cirrhosis.
Rating: Class II, Level A

Daily fixed-dose combination ledipasvir (90 mg)/sofosbuvir (400 mg) and low initial dose of RBV (600 mg, increased as tolerated) for 12 weeks is recommended for patients with HCV genotype 1 or 4 with decompensated cirrhosis.
Rating: Class IIb, Level C

Recommended regimen for patients with genotype 1 or 4 HCV infection with decompensated cirrhosis who are RBV intolerant or ineligible.
Daily daclatasvir (60 mg) and sofosbuvir (400 mg) for 24 weeks is recommended for patients with decompensated cirrhosis who are RBV intolerant or ineligible.
Rating: Class IIb, Level C,,

Recommended regimen patients with genotype 1 or 4 HCV infection with decompensated cirrhosis in whom prior sofosbuvir-based treatment has failed.
Daily fixed-dose combination ledipasvir (90 mg)/sofosbuvir (400 mg) and low initial dose of RBV (600 mg, increased as tolerated) for 24 weeks is recommended for patients with genotype 1 or 4 HCV infection with decompensated cirrhosis in whom prior sofosbuvir-based treatment has failed.
Rating: Class IIb, Level C
Avatar universal
good news for decompensated ciroses
what about ascites ?
it says nothing
444337 tn?1428073510
There are no contraindications for Ascites with regards to taking Harvoni. It should not make your condition worse or affect it in any way.

It is a very well tolerated medication.
683231 tn?1467323017
Ascitites is a symptom of decompensated cirrhosis. I have compensated cirrhosis with a small amount of ascities an edema. I treated with Harvoni for 24 weeks and Ribavirin which was added after I started for 15 of those 24 weeks.

I had only a few mild headaches and maybe a few extra aches and pains. Got a bit anemic from the ribavirin so had to dose reduce but that's about it. I was 24SVR weeks in October and am cured of hep c

Good luck to you
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