Aa
A
A
Close
Avatar universal

can pegasys elevate liver enzymes

i am in week 11 of treatment, my ALT was 180 at the beginning, after 4 weeks became 105, after 6 weeks 75
then after 8 weeks 220 after 10 weeks 904....?
so what is happen? what is wrong?
my PCR was 80000 then become undetectable afer 4 weeks
i do ANA before the beginning and was negative
what should i do?
continue the treatment or not
Read more
Cancel
Follow
Upvote - 0
3 Answers
Page 1 of 1
626749 tn?1256519302
Well.... I am no Dr and No Doctors here.
In my laymen opinion, could be autoimmune Hepatitis. But this is just a guess, at best. I could be all wrong.
Its confusing for autoimmune that your ANA was normal before TX. Maybe you developed it during TX ? Did your BX show any autoimmune hep ?
You need your Dr to figure this out. Or get a second opinion from another Dr.

What genotype are you. And how long is your tx suppose to be.
If you are a geno 2 or 3 then 12 wks tx might be enough since you had a RVR.
Have you done your 12th shot of ifn ?
Be very careful here, 904 ALT is very high. Do you have jaundice now ? Don't think you want to chance going into the thousands.

Have you got your ANA and smooth muscle antibody checked again ?
What has your Dr recommended ?
IMO, You need to be watched very carefully now by a Hepatologist or at the very least a good gastro.

apache

Comment
Cancel
Comment
Avatar universal
Comment
Comment
Comment
Post Comment
Avatar universal
You should see your hepa, It is not common.
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Comment
Post Comment
Avatar universal
thank you apache
yes i done recent PCR after the last pegasys (no 11 shot) it is negative
now i done ANA, SMA,LKMA, AnDNA and the result well be tomorrow
i hobe that it well be negative
my billirubin is 1.25 this mean that it is borderline
i have two opinoin from my doctors
one said that i must stop tt for two weeks and see what well happen to liver enzymes
the other said that continue tt till the result on investigation of autoimmune hepatitis appear
actually i prefer the first opinion and i dont take the tt
and i am waitting for the result of my blood work
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Comment
Post Comment
Your Answer
Avatar universal
Answer
Do you know how to answer? Tap here to leave your answer...
Answer
Answer
Post Answer
A
A
Answer a few simple questions about your Hep C treatment journey.

Those who qualify may receive up to $100 for their time.
Explore More In Our Hep C Learning Center
image description
What Is Hepatitis C?
Learn about this treatable virus.
image description
Diagnosing Hepatitis C
Getting tested for this viral infection.
image description
Just Diagnosed? Here’s What’s Next
3 key steps to getting on treatment.
image description
Understanding Hepatitis C Treatment
4 steps to getting on therapy.
image description
Your Guide to Hep C Treatments
What you need to know about Hep C drugs.
image description
Managing Side Effects of Treatment
How the drugs might affect you.
image description
Making Hep C Treatment a Success
These tips may up your chances of a cure.
Recent Activity
Avatar universal
Blank
susan400 12 wks done! waiting for w... Comment
Feb 22
148588 tn?1465782409
Blank
desrt “It was a bright cold day i... Comment
Feb 21
317787 tn?1473362051
Blank
Dee1956 commented on spider6's status
Feb 12
Hepatitis C Community Resources