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excessive sweating body odor
I have fatty liver for some times. Last several months, I have excessive sweating and bad body odor. I was wondering if these are hvc symptoms. Thanks for the help.
Here is a link to the article I quoted:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC130934/
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC130934/
If you were tested 20 years ago, I think it would be wise to get retested. The tests are more sensitive now.
I don't know all of the intricacies about the various tests (in terms of older generation tests versus newer generation tests), however, this article from 2002 does note that the 3rd generation tests are improved over the 2nd generation tests.
In addition, there have been even newer testing methods developed since 2002, so the current tests are even more sensitive.
If it was me, I would get retested.
From the 2002 article:
"The purpose of our study was to compare the results of second- and third-generation (G2 and G3, respectively) enzyme immunoassays (EIAs) ....."
"Exposure to hepatitis C virus (HCV) is determined by testing for anti-HCV antibodies, while active infection is marked by the presence of HCV RNA by using reverse transcriptase PCR (RT-PCR). The first enzyme immunoassay (EIA) for the detection of anti-HCV antibodies, developed 12 years ago by using a recombinant HCV C100-3 peptide (9), had relatively poor specificity and sensitivity (2, 4). Seroconversion in patients with acute HCV infection is often not detected until 3 months or longer after infection (16). The second-generation (G2) assay, introduced in 1991, incorporated recombinant antigens from nonstructural regions (NS3 and NS4) together with an antigen from the core region of HCV (2, 12). The G2 EIA was superior to the G1 EIA in both sensitivity and specificity, and its use in blood banks has dramatically reduced the incidence of posttransfusion hepatitis (8). The G3 EIA, which added an NS5 epitope, should increase the reliability of the test and increase detection of anti-HCV earlier in the course of infection (5, 6)."
"The G3 EIA clearly demonstrated sensitivity and specificity superior to those of the G2 EIA. For the subset of problematic, discordant samples, the M-EIA agreed with the G3 assay eight times as frequently as it did with the G2 assay."
I don't know all of the intricacies about the various tests (in terms of older generation tests versus newer generation tests), however, this article from 2002 does note that the 3rd generation tests are improved over the 2nd generation tests.
In addition, there have been even newer testing methods developed since 2002, so the current tests are even more sensitive.
If it was me, I would get retested.
From the 2002 article:
"The purpose of our study was to compare the results of second- and third-generation (G2 and G3, respectively) enzyme immunoassays (EIAs) ....."
"Exposure to hepatitis C virus (HCV) is determined by testing for anti-HCV antibodies, while active infection is marked by the presence of HCV RNA by using reverse transcriptase PCR (RT-PCR). The first enzyme immunoassay (EIA) for the detection of anti-HCV antibodies, developed 12 years ago by using a recombinant HCV C100-3 peptide (9), had relatively poor specificity and sensitivity (2, 4). Seroconversion in patients with acute HCV infection is often not detected until 3 months or longer after infection (16). The second-generation (G2) assay, introduced in 1991, incorporated recombinant antigens from nonstructural regions (NS3 and NS4) together with an antigen from the core region of HCV (2, 12). The G2 EIA was superior to the G1 EIA in both sensitivity and specificity, and its use in blood banks has dramatically reduced the incidence of posttransfusion hepatitis (8). The G3 EIA, which added an NS5 epitope, should increase the reliability of the test and increase detection of anti-HCV earlier in the course of infection (5, 6)."
"The G3 EIA clearly demonstrated sensitivity and specificity superior to those of the G2 EIA. For the subset of problematic, discordant samples, the M-EIA agreed with the G3 assay eight times as frequently as it did with the G2 assay."
Did you test for hep c antibodies or the virus itself
None the less negative usually means negative. If you want additional piece of mind you could always retest.
We are not medical professionals here just patients living with hepatitis c and its complications
Personally I am not a medical researcher to that level to compare old testing methods vs newer ones.
My motto when in doubt check it out.
None the less negative usually means negative. If you want additional piece of mind you could always retest.
We are not medical professionals here just patients living with hepatitis c and its complications
Personally I am not a medical researcher to that level to compare old testing methods vs newer ones.
My motto when in doubt check it out.
Apologies mo_oc. I had no intention to interupt your conversation. I thought I should ask about the hvc test. Apologies again.
Apologies mo_oc. I had no intention to interupt your conversation. I thought I should ask about the hvc test. Apologies again.
Many thanks for your relies. When I was diagnosed for fatty liver 20 years ago, I did test for hvc. It came out negative. The test was second generation and I don,t know their sensitivity. Do you know how sensitive 2nd generation tests were?
Hepatitis C can cause sweating, especially night sweating, and sweating can cause odor.
Night sweating is common in infections.
One of the articles below notes that "HCV replicates in eccrine sweat glands cells and keratinocytes in healthy skin and is released into the sweat."
I know I had a lot of sweating during the night when I had Hep C. The first thing I did every morning was get in the shower because I had sweat during the night and I did have some body odor from it.
I was cured of Hep C in 2012 and I have had no (absolutely zero) night sweating since then.
If you think you may have Hep C, get tested for it. You may also want to talk to your doctor about the sweating. There could be other causes for it and you may need further testing as Jules pointed out.
http://www.hepatitiscentral.com/hcv/symptoms/chronic-hepatitis-c-symptoms/
http://www.ncbi.nlm.nih.gov/pubmed/12376961
Night sweating is common in infections.
One of the articles below notes that "HCV replicates in eccrine sweat glands cells and keratinocytes in healthy skin and is released into the sweat."
I know I had a lot of sweating during the night when I had Hep C. The first thing I did every morning was get in the shower because I had sweat during the night and I did have some body odor from it.
I was cured of Hep C in 2012 and I have had no (absolutely zero) night sweating since then.
If you think you may have Hep C, get tested for it. You may also want to talk to your doctor about the sweating. There could be other causes for it and you may need further testing as Jules pointed out.
http://www.hepatitiscentral.com/hcv/symptoms/chronic-hepatitis-c-symptoms/
http://www.ncbi.nlm.nih.gov/pubmed/12376961
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