Hepatitis C Community
13.4k Members
Avatar universal

grapefruit and Riba

Anyone know the real answer to this.  A lot of conflicting info.  I asked the person in chare of the hep c treatment and all i got was you should take Riba with food so grapfruit is ok.  I don't think they had a clue.  
4 Responses
Avatar universal
I like to drink grapefruit juice but hear that it can interfere with some prescription medications. Is that true?
Answers from Katherine Zeratsky, R.D., L.D.

Yes. Grapefruit and certain other citrus fruits and products can interfere with several kinds of prescription medications.

Don't take these interactions lightly. Some can cause potentially dangerous health problems. Check with your doctor or pharmacist before consuming any grapefruit or other citrus products if you take prescription medications. You may need to eliminate grapefruit products from your diet. Simply taking your medication and grapefruit product at different times doesn't stop the interaction.


Make sure you talk with your doctor as in the past grapefruit has not been advised.
Avatar universal
Your hep provider is in agreement with Medhelp’s ex resident HCV expert that grapefruit doesn't have interactions with Interferon & Ribavirin,
Douglas Dieterich, MD
Jun 13, 2008
It actually can increase some drug levels because of inhibiting a liver metabolic enyzme. However neither interferon or ribavirin is metabolized by that particular enzyme(p450) so it is OK to drink your grapefruit juice.

But there are many other drugs that do have interactions with grapefruit

I avoid grapefruit because it interacts with simvastatin and oxycodone. If you are taking other medications please check with the respective provider and the pharmacist about interaction with grapefruit.
7469840 tn?1409849436
Contact Gilead, they will tell you. Grapefruit interacts with most heart medications, as well as mango.
1815939 tn?1377995399
Here are a couple of links to some information and lists of foods:


Have an Answer?
Top Hepatitis Answerers
317787 tn?1473362051
683231 tn?1467326617
Auburn, WA
Learn About Top Answerers
Didn't find the answer you were looking for?
Ask a question
Answer a few simple questions about your Hep C treatment journey.

Those who qualify may receive up to $100 for their time.
Explore More In Our Hep C Learning Center
image description
Learn about this treatable virus.
image description
Getting tested for this viral infection.
image description
3 key steps to getting on treatment.
image description
4 steps to getting on therapy.
image description
What you need to know about Hep C drugs.
image description
How the drugs might affect you.
image description
These tips may up your chances of a cure.
Popular Resources
A list of national and international resources and hotlines to help connect you to needed health and medical services.
Here’s how your baby’s growing in your body each week.
These common ADD/ADHD myths could already be hurting your child
This article will tell you more about strength training at home, giving you some options that require little to no equipment.
In You Can Prevent a Stroke, Dr. Joshua Yamamoto and Dr. Kristin Thomas help us understand what we can do to prevent a stroke.
Smoking substitute may not provide such a healthy swap, after all.