Aa
A
A
Close
Avatar universal

hepatitis c and corticosteroids

i have a 55 year old patient with hepatitic c that is only 4 weeks into interon treatment ( on renal replacement therapy i.e HD ) , that has developed decreased hearing in both ears , the ENT specialist soes not think its related to treatment and has adviced a short course of oral steroids . my questions are
1) any link between the hearing loss and interferon in the literature ?
2) how safe is it give him oral steroids at this stage ?
3) is it beneficial to use viral load or liver enzymes as a guide to decide on treatment with steroids ?
Read more
Cancel
Follow
Upvote - 0
3 Answers
Page 1 of 1
Avatar universal
It would be wise for your ENT to consult with your hepatologist or doctor who is supervising your hepc treatment and perhaps your Nephrologist to see what your best course of action is.

I've have read where tinnitus (ringing in the ears) has resulted from the the hepc treatment drugs and even a few posts stating they have experienced diminished hearing while on treatment but once treatment ended hearing was restored to normal.  
Steroids are known to suppress the immune system but they're quite remarkable when needed to reduce inflammation and assist in alleviating respiratory problems. I could not advise if a short course of steroids would be safe at this juncture but certainly your hep doc could.

Trinity
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Comment
Post Comment
Avatar universal
There are no doctors on here, we're all patients :-) Just so we're clear.

Comment
Cancel
Comment
Avatar universal
Comment
Comment
Comment
Post Comment
717272 tn?1277594380
There are case studies on the internet about interferon-induced hearing loss.  Patients were usually treated with steroids (immune suppression) after stopping interferon (immune amplification) and hearing was restored.  Some patients continue interferon therapy and the hearing loss clears on it's own but some don't recover.  Do a search with the terms interferon and hearing loss to find those case-studies.

Another approach is to do intratympanic injections with corticosteroids.  The injections allow local application of corticosteroids rather than oral.  You can read more on this topic at http://emedicine.medscape.com/article/857511-print
The treatment is done by an otolaryngologist specialized in procedures and is expensive in the US, about $1500.
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Comment
Post Comment
Your Answer
Avatar universal
Answer
Do you know how to answer? Tap here to leave your answer...
Answer
Answer
Post Answer
A
A
Answer a few simple questions about your Hep C treatment journey.

Those who qualify may receive up to $100 for their time.
Explore More In Our Hep C Learning Center
image description
What Is Hepatitis C?
Learn about this treatable virus.
image description
Diagnosing Hepatitis C
Getting tested for this viral infection.
image description
Just Diagnosed? Here’s What’s Next
3 key steps to getting on treatment.
image description
Understanding Hepatitis C Treatment
4 steps to getting on therapy.
image description
Your Guide to Hep C Treatments
What you need to know about Hep C drugs.
image description
Managing Side Effects of Treatment
How the drugs might affect you.
image description
Making Hep C Treatment a Success
These tips may up your chances of a cure.
Recent Activity
Avatar universal
Blank
mikesimon commented on susan400's status
Feb 23
Avatar universal
Blank
susan400 12 wks done! waiting for w... Comment
Feb 22
148588 tn?1465782409
Blank
desrt “It was a bright cold day i... Comment
Feb 21
Hepatitis C Community Resources