Aa
hepc
genotype 1b what is the side effect if i drink alcohol with the treatment?
Treatment outcome in relation to alcohol consumption during hepatitis C therapy: an analysis of the Swiss Hepatitis C Cohort Study.
Bruggmann P, Dampz M, Gerlach T, Kravecz L, Falcato L.
SourceARUD Zurich, Konradstr. 32, 8005 Zurich, Switzerland. [email protected]
Abstract
BACKGROUND: Adherence to hepatitis C treatment is influenced by alcohol as is the action of interferon; yet the clinical significance of the latter remains unclear. The aim of our study was to investigate the influence of ongoing alcohol intake on sustained viral response (SVR) rates in adherent patients receiving hepatitis C treatment.
METHODS: A retrospective analysis of patients treated with antiviral therapy for hepatitis C infection who were enrolled in the Swiss Hepatitis C Cohort Study was completed. Patients were eligible for the study if they had their HCV RNA tested 6 months following treatment completion and at least one cohort follow-up visit during HCV therapy, documenting the consumed amount of alcohol. They were assigned to three groups according to the amount of alcohol consumption: group A without alcohol consumption, group B 24 g/d alcohol.
RESULTS: 554 patients were included. Patients with at least 80% of the scheduled cumulative dose and duration did not significantly differ between the three groups. SVR rates according to alcohol consumption were 60% for non-drinkers (group A), 57% in group B and 50% in group C. No significant negative influence from alcohol consumption during therapy was observed in the multiple regression analysis for treatment success.
CONCLUSION: In this evaluation, we demonstrated comparable SVR rates in non-drinkers and in patients with daily amounts of alcohol intake up to 24 g during hepatitis C therapy.
http://www.ncbi.nlm.nih.gov/pubmed/20334985
Bruggmann P, Dampz M, Gerlach T, Kravecz L, Falcato L.
SourceARUD Zurich, Konradstr. 32, 8005 Zurich, Switzerland. [email protected]
Abstract
BACKGROUND: Adherence to hepatitis C treatment is influenced by alcohol as is the action of interferon; yet the clinical significance of the latter remains unclear. The aim of our study was to investigate the influence of ongoing alcohol intake on sustained viral response (SVR) rates in adherent patients receiving hepatitis C treatment.
METHODS: A retrospective analysis of patients treated with antiviral therapy for hepatitis C infection who were enrolled in the Swiss Hepatitis C Cohort Study was completed. Patients were eligible for the study if they had their HCV RNA tested 6 months following treatment completion and at least one cohort follow-up visit during HCV therapy, documenting the consumed amount of alcohol. They were assigned to three groups according to the amount of alcohol consumption: group A without alcohol consumption, group B 24 g/d alcohol.
RESULTS: 554 patients were included. Patients with at least 80% of the scheduled cumulative dose and duration did not significantly differ between the three groups. SVR rates according to alcohol consumption were 60% for non-drinkers (group A), 57% in group B and 50% in group C. No significant negative influence from alcohol consumption during therapy was observed in the multiple regression analysis for treatment success.
CONCLUSION: In this evaluation, we demonstrated comparable SVR rates in non-drinkers and in patients with daily amounts of alcohol intake up to 24 g during hepatitis C therapy.
http://www.ncbi.nlm.nih.gov/pubmed/20334985
There is a study done in Switzerland on treating previous alcoholics.
I believe they compared those who stopped during tx and those who continued.
Don`t have it handy right now if I find again I will post it.
b
I believe they compared those who stopped during tx and those who continued.
Don`t have it handy right now if I find again I will post it.
b
Did you ask your Doc ? If you did you'd already know the answer ...
Drinking at all , is a big No No while on Tx ... it used to be recommended to stop drinking at least 6 months before starting Tx .. with the new PI's not sure about this ...
There is plenty of Data supporting this subject here in this forum and online .. just use the search feature & look in this forum and around the internet.
Alcohol increases/speeds up viral replication .. hard on the liver too .. the last thing you want.
Or , ask your Doc, no one in this forum is a doctor .....
Drinking at all , is a big No No while on Tx ... it used to be recommended to stop drinking at least 6 months before starting Tx .. with the new PI's not sure about this ...
There is plenty of Data supporting this subject here in this forum and online .. just use the search feature & look in this forum and around the internet.
Alcohol increases/speeds up viral replication .. hard on the liver too .. the last thing you want.
Or , ask your Doc, no one in this forum is a doctor .....
Well How much alcohol do you plan on drinking? like only once or some every day ?? Have you done it already? Do you get drunk easier on tx Seems kinda dumb to drink and tx but I am sure some people do it hope some one comes on with some statistics but I have never seen any but if you fail tx you will most likely feel like if you didn't drink maybe you would have been successful?
your body
baja
your body
baja
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