Your friend's doctor should have known...
The package insert (FDA approved label) for Nexium (esomeprazole) contains...
"Before taking Nexium® (esomeprazole magnesium), you should let your healthcare provider know if you:
* Have liver disease or liver failure...
* If you have severe liver disease, you should not exceed a daily dose of Nexium 20 mg."
Your friend should be seeing a gastoenterologist or better still a hepatologist. NOT a primary care physician. A PCP is not qualified to treat someone with cirrhosis.
They should be asking their doctor if they can take a medicine or not. Anyone with cirrhosis needs to consult with their doctor when ever they make any change to their meds, vitamins, supplements, diet, etc. Only their doctor knows the complete status of their health. We are doctors here. Cirrhosis can be a life threatening illness and is nothing to be taken lightly.
Good luck to your friend.
I agree with HectorSF...but I would like to point out a typo in his post. Instead of "We are doctors here." It should have said: "We are NOT doctors here." You probably already knew that but I thought it was important enough to point out for clarity sake.