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Avatar universal

losing weight

Hi hubby on wk20 on Tues out of 24wk when he finished with the teleprevir his appetite came back but he is still losing weight so far he as lost over 2 stone and we cant understand why when he eating so well.  Is it the sx of the other drugs i know he is really struggling with tx at moment extreme fatigue and head all over the place any info would be great many thanks Jules
11 Responses
Avatar universal
You might want to have his thyroid checked.  If they did check it recently have them check it again.
Avatar universal
thanx no he asnt had his thyroid tested  so it worth a try. Thank-you for replying
3159077 tn?1356031131
I think it's a common to lose weight on treatment and I lost 20 pounds during my 24 weeks of treatment. I also did Incivek and continued to lose weight after it was over. Everything tasted bad, I had no appetite, and I was incapacitated by fatigue due to anemia. I couldn't concentrate on anything either and noise and light bothered me. To have a conversation was a major undertaking because I had to process the input and think of an answer and make my lips move. All of it was too much effort sometimes. So I think what your husband is going through sounds about right to me.
1815939 tn?1377991799
I think it is the Interferon and Riba. People lost weight on Tx before the PI's were ever in use. Personally, I lost 70 pounds but I was very happy about it. I needed to lose that weight. I continued to lose after Tx for a couple of months, but more slowly. But now I am no longer losing weight, even though I wish I was. LOL.

I am sure he will regain his weight after he is off Tx.
Avatar universal
I agree with jules2551.  Hepatitis C treatment effects your thyroid.  It starting to sound like a common side effect.  Everyone who is on treatment or post treatment should go get a thyroid function test BEFORE moving on to other causes.
1747881 tn?1546175878
I lost about 20 -25 lbs over 48 wks w/inc, I gained it back in the first 6 months after tx so I 'm right back where I started
Avatar universal
Im probably the only one I know that gained weight while on treatment. :(
Avatar universal
No your not!  I gained weight on cancer chemotherapy to.  Weird things
do happen. :)
766573 tn?1365166466
I gained 25 pounds the first time I treated. This was when I treated dual therapy with the Peg & Riba.

I read a few posts that said a high-fat meal increased relative bioavailability of Riba by a factor of 1.46, consistent with the value obtained from a previous noncompartmental analysis...
Can't find that old post but here is this one:
http://www.medhelp.org/posts/Hepatitis-C/Ribavirin-Absorption-Studies/show/1627178

I went totally overboard. I was hyperthyroid that time so I did not think I would gain but boy-oh-boy did. Oddly I was Hypo on the Incivek and I lost weight.

Either way (gain or lose) I would not stress over much about it if the doctor is not concerned.
Avatar universal
hi everybody just want to say thank-you to all of you for taking the time to reply much appreciated.FOUR WEEKS TO GO!!
4652753 tn?1364581946
That is such great news that your hubby only has 4 weeks to go!  I can't stop eating and while there are days I don't feel hungry I seem to do okay since I have gained 9 lbs so far (one a week) :-)  Hang in there and again count it down :-)
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