losing weight

[cheflady]

Hi hubby on wk20 on Tues out of 24wk when he finished with the teleprevir his appetite came back but he is still losing weight so far he as lost over 2 stone and we cant understand why when he eating so well.  Is it the sx of the other drugs i know he is really struggling with tx at moment extreme fatigue and head all over the place any info would be great many thanks Jules

[lrup1952]

That is such great news that your hubby only has 4 weeks to go!  I can't stop eating and while there are days I don't feel hungry I seem to do okay since I have gained 9 lbs so far (one a week) :-)  Hang in there and again count it down :-)

[cheflady]

hi everybody just want to say thank-you to all of you for taking the time to reply much appreciated.FOUR WEEKS TO GO!!

[Idyllic]

I gained 25 pounds the first time I treated. This was when I treated dual therapy with the Peg & Riba.

I read a few posts that said a high-fat meal increased relative bioavailability of Riba by a factor of 1.46, consistent with the value obtained from a previous noncompartmental analysis...
Can't find that old post but here is this one:
http://www.medhelp.org/posts/Hepatitis-C/Ribavirin-Absorption-Studies/show/1627178

I went totally overboard. I was hyperthyroid that time so I did not think I would gain but boy-oh-boy did. Oddly I was Hypo on the Incivek and I lost weight.

Either way (gain or lose) I would not stress over much about it if the doctor is not concerned.

[dontworry_behappy]

No your not!  I gained weight on cancer chemotherapy to.  Weird things
do happen. :)

[sammyandb]

Im probably the only one I know that gained weight while on treatment. :(

[hrsepwrguy]

I lost about 20 -25 lbs over 48 wks w/inc, I gained it back in the first 6 months after tx so I 'm right back where I started

[dontworry_behappy]

I agree with jules2551.  Hepatitis C treatment effects your thyroid.  It starting to sound like a common side effect.  Everyone who is on treatment or post treatment should go get a thyroid function test BEFORE moving on to other causes.

[pooh55811]

I think it is the Interferon and Riba. People lost weight on Tx before the PI's were ever in use. Personally, I lost 70 pounds but I was very happy about it. I needed to lose that weight. I continued to lose after Tx for a couple of months, but more slowly. But now I am no longer losing weight, even though I wish I was. LOL.

I am sure he will regain his weight after he is off Tx.

[Reidmusic]

I think it's a common to lose weight on treatment and I lost 20 pounds during my 24 weeks of treatment. I also did Incivek and continued to lose weight after it was over. Everything tasted bad, I had no appetite, and I was incapacitated by fatigue due to anemia. I couldn't concentrate on anything either and noise and light bothered me. To have a conversation was a major undertaking because I had to process the input and think of an answer and make my lips move. All of it was too much effort sometimes. So I think what your husband is going through sounds about right to me.

[cheflady]

thanx no he asnt had his thyroid tested  so it worth a try. Thank-you for replying

[jules2551]

You might want to have his thyroid checked.  If they did check it recently have them check it again.