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meds i can take with visteris

Hello everyone. please help. My doctors are a little slow in telling me what high blood medications I can take with visteris (the 3rd drug after interferon and ribovarin) and what bph (enlarged prostate) med i can take. my hep doctor insists I can't take rapaflow (bph) or amlodopine (high blood pressure). If you have had a similar experience or can help please respond. God bless you and my prayers for your recoveries.
7 Responses
1815939 tn?1377995399
Here is what drugs.com says about the drugs you are taking and how they would interact with triple med treatment with Victrellis:

Drug Interactions Results

Drug interactions for the following 5 drug(s):

Pegasys (peginterferon alfa-2a)
Rapaflo (silodosin)
Victrelis (boceprevir)

For Consumers:

Interactions between your selected drugs
silodosin ↔ boceprevir

Applies to: Rapaflo (silodosin), Victrelis (boceprevir)

Using silodosin together with boceprevir is not recommended. Combining these medications may significantly increase the blood levels and effects of silodosin. This may cause blood pressure to fall excessively and heart rate to increase, especially when you rise from a sitting or lying position. The risk of other side effects such as dizziness, lightheadedness, fainting, headache, flushing, nasal congestion, heart palpitations, and priapism (prolonged and painful erection unrelated to sexual activity) may also increase. Let your doctor know if you develop these symptoms while using silodosin and they do not go away on their own or they become troublesome. Avoid driving or operating hazardous machinery until you know how the medication affects you, and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

amlodipine ↔ boceprevir

Applies to: amlodipine, Victrelis (boceprevir)

Boceprevir may increase the blood levels and effects of amLODIPine. This can increase the risk of serious side effects such as irregular heart rhythm, fluid retention, swelling, heart failure, and excessively low blood pressure. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. You should seek immediate medical attention if you experience sudden, unexplained weight gain; swelling of the hands, ankles, or feet; chest pain; or difficulty breathing during treatment with these medications. Avoid driving or operating hazardous machinery until you know how the medications affect you, and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

For Professionals:

Interactions between your selected drugs
silodosin ↔ boceprevir

Applies to: Rapaflo (silodosin), Victrelis (boceprevir)

CONTRAINDICATED: Coadministration with potent inhibitors of CYP450 3A4 may significantly increase the plasma concentrations of silodosin, which is primarily metabolized by the isoenzyme. In a pharmacokinetic study, administration of a single 8 mg dose of silodosin with the potent CYP450 3A4 inhibitor ketoconazole (400 mg) resulted in a 3.8-fold increase in silodosin peak plasma concentration (Cmax) and a 3.2-fold increase in systemic exposure (AUC).

MANAGEMENT: Concomitant use of silodosin with potent CYP450 3A4 inhibitors such as itraconazole, ketoconazole, voriconazole, nefazodone, delavirdine, protease inhibitors, and ketolide and certain macrolide antibiotics is considered contraindicated.

amlodipine ↔ boceprevir

Applies to: amlodipine, Victrelis (boceprevir)

MONITOR: Coadministration with the hepatitis C virus (HCV) NS3/4A protease inhibitors, boceprevir and telaprevir, may increase the plasma concentrations and pharmacologic effects of calcium channel blockers, especially the dihydropyridines (e.g., amlodipine, felodipine, nicardipine, nifedipine, nisoldipine). The mechanism involves inhibition of intestinal and hepatic CYP450 3A4, the isoenzyme primarily responsible for the metabolic clearance of most calcium channel blockers. In 19 study subjects, administration of a single 5 mg dose of amlodipine during treatment with telaprevir (750 mg every 8 hours for 7 days) increased the amlodipine peak plasma concentration (Cmax) and systemic exposure (AUC) by an average of 27% and 179%, respectively, compared to administration alone. No data are available for boceprevir; however, a similar interaction is expected.

MANAGEMENT: Close monitoring of clinical response and tolerance is recommended if calcium channel blockers are used in combination with boceprevir or telaprevir. Dosage reduction may be required for the calcium channel blocker, particularly if it is a dihydropyridine. Patients should be advised to seek medical attention if they experience edema or swelling of the lower extremities; sudden, unexplained weight gain; difficulty breathing; chest pain or tightness; or hypotension as indicated by dizziness, fainting, or orthostasis.
Avatar universal
thank you for your quick response. What I'm looking for are the hbp and bph meds I can take. thanks
1815939 tn?1377995399
As far as which drugs you can take, that is something you and your doctor are going to have to figure out. Your doctor knows your medical problems. All drugs do not work on all people. Many people have good results from some drugs and yet have poor results from others. Your doctor should know any other medical problems that you have and which drugs may be the best possible drugs to take instead of the drugs you are now taking. One size does not fit all.

If you have questions about a drug that someone suggests you can go to the following site and check the interactions between the suggested drug and the drugs you will be taking. But in the long run, your doctor need to figure out which drug is best for your medical condition and get you on the best drug for you.


Avatar universal
thank  you
1815939 tn?1377995399
The problem in listing blood pressure meds that you can take is that there are a lot of them and people respond differently. In addition, the doctor usually picks a certain medication or a certain category of medications for a reason.

You are on a calcium channel blocker but none of us knows why your doc picked that drug. We would be taking stabs in the dark suggesting any number of drugs that may not be indicated in your case. Your doctor needs to determine exactly what properties are needed in the medication you will take and then be sure that he prescribes one that is compatible with the Hep C meds.

I am not trying to avoid your question but here is a list of drugs for high blood pressure. You can see what I mean about there being manmy drugs.

Hypertension Drugs
Chemical and Brand Names
By Richard N. Fogoros, M.D., About.com Guide
Updated June 30, 2011

The following is a list of the most common drugs and drug combinations used to treat hypertension (high blood pressure). With so many approved drugs to choose from, settling on the "best" drug(s) for you will take careful collaboration between you and your doctor.

Diuretics ("water pills") increase the amount of sodium and water excreted into the urine by the kidneys. It is thought that they lower blood pressure mainly by reducing the volume of fluid in the blood vessels.

Diuretics commonly used for hypertension:

    Acetazolamide - Diamox
    Chlorthalidone - Thalitone
    Hydrochlorothiazide - HydroDiuril, also sold as Microzide and Esidrix
    Indapamide - Lozol
    Metolazone - Zaroxolyn, also sold as Mykrox

Diuretics less commonly used for hypertension:

    Amiloride hydrochloride - Midamor
    Bumetanide - Bumex
    Ethacrynic acid - Edecrin
    Furosemide - Lasix
    Spironolactone - Aldactone
    Torsemide - Demadex
    Triamterene - Dyrenium

Beta blockers block the effect of adrenaline on the cardiovascular system, slow the heart rate, and reduce stress on the heart and the arteries.

    Acebutolol - Sectral
    Atenolol - Tenormin
    Betaxolol - Kerlone
    Bisoprolol - Zebeta, also sold as Ziac
    Carteolol - Cartrol
    Carvedilol - Coreg
    Labetalol - Normodyne, also sold as Trandate
    Metoprolol - Lopressor, also sold as Toprol
    Nadolol - Corgard
    Penbutolol - Levatol
    Propranolol - Inderal, Inderal LA
    Timolol - Blocadren

Calcium Channel Blockers
Calcium channel blockers can reduce blood pressure by dilating the arteries and, in some cases, reducing the force of the heart's contractions.

    Amlodipine - Norvasc, also sold as Caduet and Lotrel
    Diltiazem - Cardizem, also sold as Dilacor and Tiazac
    Felodipine - Plendil
    Isradipine - DynaCirc
    Nicardipine - Cardene
    Nifedipine - Procardia XL, also sold as Adalat
    Nisoldipine - Sular
    Verapamil hydrochloride - Isoptin, also sold as Calan, Verelan, and Covera

Angiotensin Converting Enzyme Inhibitors
The angiotensin converting enzyme inhibitors (the "ACE inhibitors") can lower blood pressure by dilating the arteries.

    Benazepril - Lotensin
    Captopril - Capoten
    Enalapril - Vasotec, also sold as Vaseretic
    Fosinopril - Monopril
    Lisinopril - Prinivil, also sold as Zestril
    Moexipril - Univasc
    Quinapril - Accupril
    Ramipril - Altace
    Trandolapril - Mavik

Angiotensin II Receptor Blockers
The angiotensin II receptor blockers (the "ARBs") also reduce blood pressure by dilating the arteries.

    Candesartan - Atacand
    Irbesartan - Avapro
    Losartan - Cozaar
    Telmisartan - Micardis
    Valsartan - Diovan

Other, Less Commonly Used Hypertension Drugs

    Clonidine - Catapres
    Doxazosin - Cardura
    Guanabenz - Wytensin
    Guanfacine - Tenex
    Hydralazine hydrochloride - Apresoline
    Methyldopa - Aldomet
    Prazosin - Minipress
    Reserpine - Serpasil
    Terazosin - Hytrin

Combination Drugs For Hypertension

    Amiloride and hydrochlorothiazide - Moduretic
    Amlodipine and benazepril - Lotrel
    Atenolol and chlorthalidone - Tenoretic
    Benazepril and hydrochlorothiazide - Lotensin HCT
    Bisoprolol and hydrochlorothiazide - Ziac
    Captopril and hydrochlorothiazide - Capozide
    Enalapril and hydrochlorothiazide - Vaseretic
    Felodipine and enalapril - Lexxel
    Hydralazine and hydrochlorothiazide - Apresazide
    Lisinopril and hydrochlorothiazide - Prinzide, also sold as Zestoretic
    Losartan and hydrochlorothiazide - Hyzaar
    Methyldopa and hydrochlorothiazide - Aldoril
    Metoprolol and hydrochlorothiazide - Lopressor HCT
    Nadolol and bendroflumethiazide - Corzide
    Propranolol and hydrochlorothiazide - Inderide
    Spironolactone and hydrochlorothiazide - Aldactazide
    Triamterene and hydrochlorothiazide - Dyazide, also sold as Maxide
    Verapamil extended release) and trandolapril - Tarka

1815939 tn?1377995399
This site gives you some names of drugs for BHP:


generic name: tamsulosin class: antiadrenergic agents, peripherally acting
generic name: tadalafil class: impotence agents
generic name: dutasteride class: 5-alpha-reductase inhibitors
generic name: doxazosin class: antiadrenergic agents, peripherally acting
generic name: finasteride class: 5-alpha-reductase inhibitors 1 review
generic name: silodosin class: antiadrenergic agents, peripherally acting

generic name: terazosin class: antiadrenergic agents, peripherally acting
generic name: dutasteride/tamsulosin class: 5-alpha-reductase inhibitors, antiadrenergic agents, peripherally acting

generic name: alfuzosin class: antiadrenergic agents, peripherally acting
generic name: prazosin class: antiadrenergic agents, peripherally acting
Prostate SR
generic name: saw palmetto class: herbal products

Cardura XL
generic name: doxazosin class: antiadrenergic agents, peripherally acting
Avatar universal
thanks again
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