rash

Question

Did anyones rash get batter after compleating the Incivek?

Advocate1955 · Accepted Answer

My husband used Eucerin body wash in the shower, Eucerin cream after the shower, and tea tree oil on blisters.  He took Hydroxyzine and also had a prescription for Triamcinolone ointment.  The Incivek rash began about mid way through week 2 and lasted until the end of the 12 weeks on Incivek.  When he finished Incivek, it gradually improved, although he had some strange skin tingles and rash-like problems for awhile still.
Advocate1955

Advocate1955 · Answer

Glad to hear your rash has cleared up and that you're doing well on your treatment.  You asked if the Incivek rash spread to peoples' faces.  Yes, my husband's Incivek rash spread to his face.  I would describe his rash as moderate.  It seemed severe at the time, but it never really covered a super large portion of his body all at the same time.  It seemed to move around, starting on his abdomen, moving to his chest, then to his face and arms, then to his back, and then to his legs if I remember correctly.  It didn't really "spread" per se, it moved.  It started around week 2 and lasted through about week 10, then it improved slightly, and gradually went away after Incivek.  It was definitely difficult.
Advocate1955

gardengirl965 · Answer

Hope your rash has cleared up by now. I am in the beginning of week 21 of a 24 week treatment. Most of my rash has cleared up except on the front of my lower legs, but that area is getting smaller. When the skin with the rash peeled off, it was just like I had had a chemical peel. I've never had smoother skin! The skihn on my face and arms looks like I've been to rthe spa! lol Now if I could get some new better hair to grow back in I'll be on top of things. My itching has subsided too. But when one set of side effects goes away, a new one takes it's place. I have been getting bad neusea the last couple of days. Hope you are doing ok.

angel216 · Answer

I had a horrible rash on my arms during INC.  My arms looked liked I had been attacked by mosquitos non stop.  Thankfully after finishing INC the itching stopped and my arms are finally healing....good luck

gardengirl965 · Answer

I was wondering if I have more than one kind of rash. One from Incivek and one from the Riba. I am in pretty bad shape today. Go in to the doctor this afternoon. I hope they can prescribe something for my shin rash...or I should say I Hope they prescribe! I am in the begginning of week 11 on Incivek.

gardengirl965 · Answer

Thanks for writing back. The skin on my lips and face has dried out and is peeling off and my scalp itches all the time. I put lotion my my face, but it doesn't seem to help.
I called my doctor back yesterday and he said to stop all medicine and come into the office today and let them look at me. I sure hope he knows what to do for me. I kind of got the idea they are new to all this Incivek stuff, but he does seem like a good doctor. Cross your fingers for me!

Jillko59 · Answer

It might be a RIBA rash. I was taken off RIBA for 10 days, cleared the rash and began the riba again. My body was screaming!

coeric · Answer

Yes, i did have a rash on my face and also the scalp.  the biopsies showed more than one kind of rash.  the rash on my head was more reddish than the purplish color on my legs. i think the rash on my head looked more like a allergic reaction than the systemic nature of the rash on the lower parts of the body. anyway the rash on my head was nowhere near as gross as the rash on my leges.  the clobetasol ointment worked on the rash on my head, but i required prednisone for the rash on my legs. i am in week 48 of treatment and i still have small areas of rash and itch.
eric

gardengirl965 · Answer

Did this awful rash spread to your faces? That's the only place I don't have it. I would hate to think of having something that looks this bad on my face too!!   :(

gardengirl965 · Answer

I went and looked at your pictures. I am starting to look like that. Since I was in to see my doctor this week about the rash it has spread and gotten worse! My skin hurts. The only place I don't have the rash yet is on my face. Did your rash spread to your face?

Advocate1955 · Answer

You're welcome.  I'm glad it helped.  My husband also got a few small blisters on his back from the Incivek rash, and we put tea tree oil on them.  The trick is keeping your skin cool.  Take cool showers, wear light clothing, keep your house cool, etc.  Sometimes my husband would stand in front of an open freezer door, a fan, or out in the cool night air.
Advocate1955

gardengirl965 · Answer

I was using Curel Itch defense lotion and could not stand the way it made my skin feel like there was a build up of clay or something creepy on it. I got some of the Eucerin Calming lotion after reading your comment and it is a much beter lotion. Thanks for you in put!!

maybe368 · Answer

This is going to be contra to the conventional wisdom of this, but it is my experience. I had the rash from head to toe, front and back, in ears, on palms and soles of feet. I was very close to severe, if not severe. The worst came between monthly doctor visits so my doctor never saw the worst of it. I think she may have stopped the Incyvek. This was from about week 8 to 12. After the end of the incyvek the rash persisted and did not go away until I started exposing it to the sun. I live in Phoenix so there is no lack of that.I started going out back in tighty whities and exposing the rash, starting for about 3 minutes and working up to about 30 minutes. The rash responded better to this than the hydroxine and triamcinolone. It was gone in less than 2 weeks.I know that most say to avoid the sun, but in my case it was the opposite. We are all different. By the way, I am on week 27 of 48 and und since week 4...Mark

flcyclist · Answer

As you can see below, about 1/3 of the patients treating with Inf/Riba alone did still experience the rash.  I was unfortunately one of them.  Heat and sweating were the main triggers so do your best to stay cool.  But it was managable with hydrocortizone and otc antihistamines.  As eric mentioned above, many used hydroxyzine (atarax) to successfully control the more severe rash.  

The safety data for telaprevir (Incivek, Vertex) show that rash occurs in 56% of patients treated with telaprevir, compared to 34% of patients treated with peginterferon and ribavirin alone. Similarly, pruritus has been reported
in 47% of patients who received telaprevir-based triple therapy, compared to 28% of patients treated with peginterferon and ribavirin."

http://www.clinicaladvances.com/article_pdfs/gh-article-201107-hep.pdf

Idyllic · Answer

Greetings. I remember in the beginning the common belief seemed to be the rash would resolve on it's own the longer you are off the  Incivek. That just seemed to be the assumption for a short while there - Independent what is in the studies.

Eventually more and more people who treated & developed the rash would post an experience similar to what coeric said: When the rash reaches a certain point it does not seem to really totally go away until you treat it. 

I realize you asked the question anecdotally but just in case you are treating: the rash is a side effect that should be taken seriously and treated aggressively. 
Take care♫

coeric · Answer

Hi, i was pulled off incevik at week 10 due to the rash. by week 12, with the help of prednisone, my skin looked much better.  the rash started the first week of treatment, and now at week 47, i am still experiencing mild itching and small patches of rash. Now, i control the itch with hydroxyzine and the  small skin eruptions with clobetasol.  The first 11 weeks were the worst.  i posted some photos of the rash on my home page. it does get better. 
blessings
eric