Aa
A
A
A
Close
Hepatitis C Community
13.4k Members
Avatar universal

riba pkg insert (part 1) re. riba dose

I am GT 1 and my md only wants to give me 800 mg of riba because I weigh 115 lbs.  Why ?!

•for the treatment of chronic hepatitis C infection (monoinfection) in combination with interferon alfa-2b in patients previously untreated with interferon alpha:
NOTE: Consider response prognostic factors, HCV genotype, viral load, and disease progression evidence such as hepatic inflammation and fibrosis when deciding to treat a pediatric patient. Weigh treatment benefits against potential safety risks identified in clinical trials (see Contraindications/Precautions).
NOTE: The American Association for the Study of Liver Diseases (AASLD) recommends a peginterferon alfa product in combination with ribavirin as the preferred therapy for chronic hepatitis C infection.[20505]
Oral dosage (capsules or oral solution):
Adults > 75 kg: 600 mg PO twice daily (in the morning and evening) plus interferon alfa-2b 3 million international units SC/IM 3 times per week for 24—48 weeks; consider treatment discontinuation if an HCV-RNA value below the level of detection has not been achieved at 24 weeks. There are no safety or efficacy data on treatment longer than 48 weeks.[29161]
Adults  73 kg: 15 mg/kg/day PO or 1200 mg/day PO given in 2 divided doses (in the morning and evening) plus interferon alfa-2b 3 million international units SC/IM 3 times per week. The duration of treatment for genotype 1 is 48 weeks; consider treatment discontinuation if an HCV-RNA value below the level of detection has not been achieved at 24 weeks. The duration of treatment for genotype 2 or 3 is 24 weeks. NOTE: The manufacturer does not provide a specific maximum dosage for pediatric patients; however, for this indication, the maximum dosage for adults weighing > 75 kg is 1200 mg/day.[29161]
Children and Adolescents 62—73 kg: 15 mg/kg/day PO or 1000 mg/day PO given in 2 divided doses (in the morning and evening) every day plus interferon alfa-2b 3 million international units SC/IM 3 times per week. The duration of treatment for genotype 1 is 48 weeks; consider treatment discontinuation if an HCV-RNA value below the level of detection has not been achieved at 24 weeks. The duration of treatment for genotype 2 or 3 is 24 weeks.[29161]
Children and Adolescents 60—61 kg: 15 mg/kg/day PO or 1000 mg/day PO given in 2 divided doses (in the morning and evening) every day plus interferon alfa-2b 3 million international units/m2 SC 3 times per week. The duration of treatment for genotype 1 is 48 weeks; consider treatment discontinuation if an HCV-RNA value below the level of detection has not been achieved at 24 weeks. The duration of treatment for genotype 2 or 3 is 24 weeks.[29161]
Children and Adolescents 47—59 kg: 15 mg/kg/day PO or 800 mg/day PO given in 2 divided doses (in the morning and evening) plus interferon alfa-2b 3 million international units/m2 SC 3 times per week. The duration of treatment for genotype 1 is 48 weeks; consider treatment discontinuation if an HCV-RNA value below the level of detection has not been achieved at 24 weeks. The duration of treatment for genotype 2 or 3 is 24 weeks.[29161]
Children and Adolescents >= 3 years and < 47 kg: 15 mg/kg/day PO divided twice daily plus interferon alfa-2b 3 million international units/m2 SC 3 times per week. The duration of treatment for genotype 1 is 48 weeks; consider treatment discontinuation if an HCV-RNA value below the level of detection has not been achieved at 24 weeks. The duration of treatment for genotype 2 or 3 is 24 weeks.[29161]
Neonates, Infants, and Children  75 kg: 600 mg PO twice daily (in the morning and evening) plus interferon alfa-2b 3 million international units SC/IM 3 times per week for 24 weeks. There are no safety or efficacy data on treatment longer than 24 weeks.[29161]
Adults  73 kg: 15 mg/kg/day PO or 1200 mg/day PO given in 2 divided doses (in the morning and evening) plus interferon alfa-2b 3 million international units SC/IM 3 times per week. The duration of treatment for genotype 1 is 48 weeks; consider treatment discontinuation if an HCV-RNA value below the level of detection has not been achieved at 24 weeks. The duration of treatment for genotype 2 or 3 is 24 weeks. NOTE: The manufacturer does not provide a specific maximum dosage for pediatric patients; however, for this indication, the maximum dosage for adults weighing > 75 kg is 1200 mg/day.[29161]
Children and Adolescents 62—73 kg: 15 mg/kg/day PO or 1000 mg/day PO given in 2 divided doses (in the morning and evening) every day plus interferon alfa-2b 3 million international units SC/IM 3 times per week. The duration of treatment for genotype 1 is 48 weeks; consider treatment discontinuation if an HCV-RNA value below the level of detection has not been achieved at 24 weeks. The duration of treatment for genotype 2 or 3 is 24 weeks.[29161]
Children and Adolescents 60—61 kg: 15 mg/kg/day PO or 1000 mg/day PO given in 2 divided doses (in the morning and evening) every day plus interferon alfa-2b 3 million international units/m2 SC 3 times per week. The duration of treatment for genotype 1 is 48 weeks; consider treatment discontinuation if an HCV-RNA value below the level of detection has not been achieved at 24 weeks. The duration of treatment for genotype 2 or 3 is 24 weeks.[29161]
Children and Adolescents 47—59 kg: 15 mg/kg/day PO or 800 mg/day PO given in 2 divided doses (in the morning and evening) plus interferon alfa-2b 3 million international units/m2 SC 3 times per week. The duration of treatment for genotype 1 is 48 weeks; consider treatment discontinuation if an HCV-RNA value below the level of detection has not been achieved at 24 weeks. The duration of treatment for genotype 2 or 3 is 24 weeks.[29161]
Children and Adolescents >= 3 years and < 47 kg: 15 mg/kg/day PO divided twice daily plus interferon alfa-2b 3 million international units/m2 SC 3 times per week. The duration of treatment for genotype 1 is 48 weeks; consider treatment discontinuation if an HCV-RNA value below the level of detection has not been achieved at 24 weeks. The duration of treatment for genotype 2 or 3 is 24 weeks.[29161]
Neonates, Infants, and Children < 3 years: Safety and efficacy have not been established.
25 Responses
179856 tn?1333550962
800 mg is appropriate for you weight - I weighed ten pounds more and that is what was prescribed originally for me.  I dont know about kgs and all but yes it is correct I would think.
Avatar universal
I weighed 120 pounds during my treatment and my riba dose was also 800.  My treatment was successful.
96938 tn?1189803458
You weigh 52 kg.  52 x 15/mg per kg is 780 mg riba per day.  That seems about right
Avatar universal

It would seem that at 1000 your lst treament you were somewhat over prescribed...however you mentioned your HGB. stayed in safe territory...so possibly discuss this with your doctor ..with his views...however don"t forget..this time with the P.I  your HGB.. may take more of a hit..
Will
Avatar universal
i guess i am afraid not to take the 1000 mg which is what I took the first time.
dave spectra sent this to me which corresponds to the 1000 mg:
http://www.drugs.com/dosage/copegus.html

Avatar universal
Dosage chart.
http://www.drugs.com/dosage/ribavirin.html

Pounds to kg conversion.
http://www.metric-conversions.org/weight/pounds-to-kilograms.htm

Myself i would want a 1000 mg for at least the first 4 weeks going by your last tx. results....... But i'm one to take a sledge hammer approach.......Wishing you the best.

Have an Answer?
Top Hepatitis Answerers
317787 tn?1473362051
DC
683231 tn?1467326617
Auburn, WA
Learn About Top Answerers
Didn't find the answer you were looking for?
Ask a question
Answer a few simple questions about your Hep C treatment journey.

Those who qualify may receive up to $100 for their time.
Explore More In Our Hep C Learning Center
image description
Learn about this treatable virus.
image description
Getting tested for this viral infection.
image description
3 key steps to getting on treatment.
image description
4 steps to getting on therapy.
image description
What you need to know about Hep C drugs.
image description
How the drugs might affect you.
image description
These tips may up your chances of a cure.
Popular Resources
A list of national and international resources and hotlines to help connect you to needed health and medical services.
Here’s how your baby’s growing in your body each week.
These common ADD/ADHD myths could already be hurting your child
This article will tell you more about strength training at home, giving you some options that require little to no equipment.
In You Can Prevent a Stroke, Dr. Joshua Yamamoto and Dr. Kristin Thomas help us understand what we can do to prevent a stroke.
Smoking substitute may not provide such a healthy swap, after all.