Can I use Ibuprofen with State 0

[scratchinghead]

I am Level 2, Stage 0 and I also have bad left knee. Osteo arthritis, wore out the padding dancing the jitterbug.

Is taking a couple Ibuprofen going to cause an liver damage? I'm thinking about 4 a day for a week while I am at a ski camp in Colorado (my last hurrah before treatment).

I am scared to death of doing anything to ruin my good status with this desease.

[scratchinghead]

jamimapuddle: Level 2 means I've probably had it 20 years (I think it goes 1 thru 4). So, I've had it for 20 years and have no liver damage. Whatever I use will probably be no more than 800mg in 24 hours.

BThompson4: thanks for the link, I guess if I have to I'll take an acetomenaphen. We're talking 5 days of skiing and I already am a weenie. I might not need to take anything. Here is an excerpt from your link and maybe it will help others:

An under-appreciated cause of unexpected, sudden, steep rise in the liver transaminases is NSAIDs, as evidenced by these cases. In the three cases described, each patient reported the use of ibuprofen within 1 wk before a greater than 5-fold increase occurred in the liver transaminases. The fact that these three cases occurred with ibuprofen is alarming, because this drug is thought to be the safest NSAID in terms of liver toxicity (2,5). These three cases involved patients with a spectrum of HCV disease from relatively mild hepatitis to cirrhosis, and suggest that toxicity from ibuprofen in patients with HCV is not dependent on severity of disease.
Because of the high renin state that exists in cirrhosis, NSAIDs are known to reduce creatinine clearance secondary to marked reduction in prostaglandin E2 levels (2). Given this renal sensitivity and the possible gastrointestinal bleeding risk, NSAIDs are not usually recommended in cirrhotic patients. Frequently, acetaminophen is avoided in those with chronic liver diseases because of concern of intrinsic liver toxicity. NSAIDs are often prescribed instead for a variety of headaches or musculoskeletal complaints. No cases have been reported of hepatic injury occurring in patients with HCV, either with or without cirrhosis, and no active alcohol use when taking less than or equal to 2 g/24 h of acetaminophen (19). Based on this report, the recommendation on the use of analgesics to patients infected with HCV should be to avoid NSAIDs when possible and, when analgesics are needed, to take acetaminophen at a dose of less than or equal 2 g/24 h. If NSAIDs are deemed necessary, careful monitoring of the liver function tests should take place with monthly testing (at least) for the first 3 months of use and then every 3 months thereafter. Further study is needed of a large group of patients with hepatitis C to determine incidence of NSAID toxicity in this patient population and to develop a cost-effective approach to NSAID use and follow-up in this population

[jamimapuddle]

My hep doc said it was fine, just don't exceed 2400mg in 24hours. What is Level 2? All I know is that I've got stage 2 fibrosis. Both my husband and I take ibuprofen with  regularity and neither of us have sky high ALT/AST levels. Mine are just slightly elevated, and my husbands' is normal.

[BThompson4]

I would not take ibuprofen for very long with the liver damage you have.

http://www.hepatitis-central.com/hcv/hepatitis/ibuprofen.html

[nygirl7]

If you had to take meds you can take the meds...just try and take as few as possible like always cause you might not have any liver damage now but you COULD in the future so you just wanna be careful.  but it won't hurt you.

Hey we have to LIVE while we do treatment... :)

[scratchinghead]

I meant stage 0, sheez