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Does Gilead hold the key to CURE!
I would be interested to know how many have signed the petition at Change.org targeting Gilead Sciences (GS-7977) to partner with Bristol-Myers (BMS-790052 daclatasvir) and to put "patients before profits". Excerpts pasted below from various searches on the internet:
"Gilead, Bristol Hep C Drug Data at EASL: 100% Cure Rate with Bristol's phase II study of daclatasvir plus Gilead's GS-7977 in patients with genotypes 1, 2, and 3: SVR4 (early cure) rate in the genotype 1 patients: 100%. In genotype 2/3 patients, the SVR4 rate was 91%."
"But the combination might not find its way to the market because one pill is owned by Gilead Sciences and the other by Bristol-Myers Squibb. The companies have not agreed to collaborate, to the chagrin of some doctors."
"Dr. Douglas J. Manion, a senior vice president for Bristol-Myers, said his company was “keen” on working with Gilead but that “thus far, they have been unwilling to engage in that collaboration.”
If you have not signed it, I am curious to know your reasons. I have been following this forum since I was diagnosed last September, and I have spent hundreds, probably thousands of hours searching for treatment without the side effects of interferon and/or ribavirin.. And now there appears to be a 100% early CURE rate for GT1s without interferon OR ribavirin, and a 91% early CURE rate for GT3s (my genotype)...with minimal side effects (nausea, headache, fatigue).
Thank you all in advance for your responses.
Link to petition:
http://www.change.org/petitions/gilead-sciences-a-phase-iii-collaboration-for-the-treatment-of-hepatitis-c
Warmest Regards,
Margaret
"Gilead, Bristol Hep C Drug Data at EASL: 100% Cure Rate with Bristol's phase II study of daclatasvir plus Gilead's GS-7977 in patients with genotypes 1, 2, and 3: SVR4 (early cure) rate in the genotype 1 patients: 100%. In genotype 2/3 patients, the SVR4 rate was 91%."
"But the combination might not find its way to the market because one pill is owned by Gilead Sciences and the other by Bristol-Myers Squibb. The companies have not agreed to collaborate, to the chagrin of some doctors."
"Dr. Douglas J. Manion, a senior vice president for Bristol-Myers, said his company was “keen” on working with Gilead but that “thus far, they have been unwilling to engage in that collaboration.”
If you have not signed it, I am curious to know your reasons. I have been following this forum since I was diagnosed last September, and I have spent hundreds, probably thousands of hours searching for treatment without the side effects of interferon and/or ribavirin.. And now there appears to be a 100% early CURE rate for GT1s without interferon OR ribavirin, and a 91% early CURE rate for GT3s (my genotype)...with minimal side effects (nausea, headache, fatigue).
Thank you all in advance for your responses.
Link to petition:
http://www.change.org/petitions/gilead-sciences-a-phase-iii-collaboration-for-the-treatment-of-hepatitis-c
Warmest Regards,
Margaret
Update: 1683 people have signed thus far. Everyone please keep sharing this link. We can do this people...we have to! Thank you all!
Well I signed it. I am apreciative of the efforts of Mdudley and athers for taking the initiative.
Among those with a need for a new drug are transplant patients. There are many of them who have failed Peg/Riba and cannot take Telaprevir or Bocep because of serious interaction with the toxic immune inhibitors they must take.
Since HEPC is the #1 reason for liver transplantation in the US, and genotype 1 is the most common genotype, I imagine that there is a great number of people currently in dire need for an effective therapy with or without interferon.
GS-7977with Daclatasvir looks like the best hope right now.
A big thanks to all on the forum for the good posts here!
Among those with a need for a new drug are transplant patients. There are many of them who have failed Peg/Riba and cannot take Telaprevir or Bocep because of serious interaction with the toxic immune inhibitors they must take.
Since HEPC is the #1 reason for liver transplantation in the US, and genotype 1 is the most common genotype, I imagine that there is a great number of people currently in dire need for an effective therapy with or without interferon.
GS-7977with Daclatasvir looks like the best hope right now.
A big thanks to all on the forum for the good posts here!
Update on petition at : (copy & paste into your browse)
www.change.org/petitions/gilead-sciences-a-phase-iii-collaboration-for-the-treatment-of-hepatitis-c#
We had over 502 signatures today for a grand toal of 1654! This is the biggest day yet and I think it is going to grow tremendously in the next few weeks.
Please sign and share this petition via emails, twitter, facebook, etc.! I believe we can do this. I believe we can pressure Gilead into collaboration with BMS...all it takes is enough signatures. So appeal to everyone you know!
Warmest regards,
Margaret
www.change.org/petitions/gilead-sciences-a-phase-iii-collaboration-for-the-treatment-of-hepatitis-c#
We had over 502 signatures today for a grand toal of 1654! This is the biggest day yet and I think it is going to grow tremendously in the next few weeks.
Please sign and share this petition via emails, twitter, facebook, etc.! I believe we can do this. I believe we can pressure Gilead into collaboration with BMS...all it takes is enough signatures. So appeal to everyone you know!
Warmest regards,
Margaret
"So heppers UNITE! There is a CURE for Hepatitis C and Gilead Sciences holds the KEY...we will make them OPEN the DOOR!"
Rah rah sis boom bah go team go!! Let's get them signatures going people and if you can't sign up for one reason or another then send out the link to friends and family to go to that link and sign up. Actually I feel if you have a facebook account you have more to worry about than change.org but that's jmho. bump bump!!
Rah rah sis boom bah go team go!! Let's get them signatures going people and if you can't sign up for one reason or another then send out the link to friends and family to go to that link and sign up. Actually I feel if you have a facebook account you have more to worry about than change.org but that's jmho. bump bump!!
Fretboard...I am so darn grateful to you! Yes...let's get the word out! I refuse to miss an opportunity to get someone to sign this petition. I got my acupunturist, hairdresser, massage therapist, Time Warner cable service guys (on a service call at my house), and many others to sign. I told both of my daughters that for Mother's day all I wanted was signatures on this petition (they got 35 of them :). I have made up fliers and left them at the post office, ATM, etc. and I post unrelentingly on FB. I have written the newspaper, one of our US Senators...anything and everything I can think of! And tomorrow my husband (he finally got permission) is putting out an office email to over 1500 employees!!! The word is starting to get out there...I have seen people's names from all over the world! We need 100,000 signatures by July 20th in order to present this petition to Gilead.
Although you are required to enter your email & address this information is not shared anywhere. As of a few minutes ago, we have 1150...hoping to see that number rise significantally in the next few days. Michael Labhard is the person who started this petition because he has a friend who had a liver transplant and desperately needs these TWO drugs just as we ALL DO! So heppers UNITE! There is a CURE for Hepatitis C and Gilead Sciences holds the KEY...we will make them OPEN the DOOR!
Warmest regards,
Margaret
Although you are required to enter your email & address this information is not shared anywhere. As of a few minutes ago, we have 1150...hoping to see that number rise significantally in the next few days. Michael Labhard is the person who started this petition because he has a friend who had a liver transplant and desperately needs these TWO drugs just as we ALL DO! So heppers UNITE! There is a CURE for Hepatitis C and Gilead Sciences holds the KEY...we will make them OPEN the DOOR!
Warmest regards,
Margaret
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