Elevated Liver Enzymes in the Thousands

[filefolder]

I can't find any info on liver enzymes in the thousands.  I see people on the Hepatitis forums with levels at or in the hundreds.  I'm still trying to figure out an AST of 3000.  I'm waiting 3 days for additional lab results but it's making me crazy.  

Can someone give me more info? or point me to another source on the internet?

Has anyone had liver enzymes in the thousands?  What was the cause? Treatment?

[willbb]

Possibly NASH(non-alcoholic steatohepatitis) or NAFLD(non-alcoholic liver disease) both of which can cause cumulative liver problems(including advanced fibrosis) which can eventually involve the kidneys. However obvoiusly further tests are needed.

good news on the neg Hep tests....hopfully your doctor can get to the bottom of your problem with further testing.

Good luck
Will

[filefolder]

Picked up test results and they are all negative (a, b, b, c).  The hep A has a negative/non-reactive, the others were all negative/negative.

Still no answers.  See specialist next Thurs.

Meantime, my liver and kidneys are in bad shape.  Why?

[nygirl7]

* Prolonged collapse of the circulatory system (shock) when the liver is deprived of fresh blood providing oxygen and nutrients

* Also, very high AST and ALT levels can be a result of severe muscle diseases."
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http://www.cholestech.com/docs/test_info/tbALTAST.pdf

Extremely high AST levels (>1000) occur in severe liver necrosis (liver cell death), skeletal muscle damage, and acute myocardial infarction (heart attack).


Ah Hector you just answered for me why I had tachycardia and such grossly high liver enzymes when I was put into the hospital recently.  The stupid GI told me I had my hepatitis back and it came and went and I went nuts on her.....after being SVR for over 5 years it was a stupid thing to say. Considering they collapsed all the veins in my arms, hands and feet I bet throwing up all that blood had something to do with the circulatory stuff.

It fits.  Thank you for posting that.

[HectorSF]

From MedicineNet.com
http://www.medicinenet.com/liver_blood_tests/page5.htm#conditions

"What conditions can cause very high aminotransferase levels?

AST and ALT serum levels in some situations can range anywhere from ten times the upper limits of normal to thousands of units/liter The highest levels of AST and ALT are found with disorders that cause rapid death of numerous liver cells (extensive hepatic necrosis). Although this degree of liver enzymes elevation is not common, it can occur in such conditions as:

* Acute viral hepatitis A or B

* Profound liver damage inflicted by toxins as from an overdose of acetaminophen (brand-name Tylenol) or mushroom poisoning

* Prolonged collapse of the circulatory system (shock) when the liver is deprived of fresh blood providing oxygen and nutrients

* Also, very high AST and ALT levels can be a result of severe muscle diseases."
--------------------------------------------------------------------------------------------------------------------------------
http://www.cholestech.com/docs/test_info/tbALTAST.pdf

Extremely high AST levels (>1000) occur in severe liver necrosis (liver cell death), skeletal muscle damage, and acute myocardial infarction (heart attack).

Good luck.
Hector

[nygirl7]

I don't know the answer to your question but dang I'd be on the phone every hour with the doctors. Mine were in the almost 300 area before I treated and that was considered very very high.  That's an awful lot of liver cell death being done to you, I think it can happen when you are in the acute stage of hepc or when things are wrong with your pancreas but I think you need a GOOD doctor to find out the CAUSE of why it's happening.

Oh and Crazy Horses was the name of an old Osmond Brother album - dont ask me how i remember that ;)