Aa
First Time Identifying Hep C
Here is a very interesting fact...just found out today from my nurse that the Liver Study Unit in Toronto,Canada is the where the first place in the world where it was first identfiied as Hep C...from being "non B"...
I think now the San Francisco Doctors stole the papers from Toronto and took all the credit....LOL
HOnest mistake, the two sound similar if you pronounce them real fast--
"DO have C " and "SKI Do "
"DO have C " and "SKI Do "
Rocker you were close, but I think it was "snowmobiles" that were discovered first in Toronto. http://www.skidoorentals.com/locations.html
I was trying to google on this topic too,but could find nothing...i am just repeting what my study nurse told me...she tells me she has been treating hep c patients for 29 years..ive know her for almost 5 years myself...she is an honest person
I don't know Trinity - really, I really don't know. Maybe it was in Canada but I could find nothing supporting that statement. I was reading about non a non b and the discovery of HCV recently so it interested me - well, I won't go that far. I doubted it, that's all.
Mike
Mike
The distance between Toronto and San Francisco can't be more than....2500 miles? I can see where the confusion might come in.
".....Yet virologists have been eyeing the disease from the beginning, hoping one day to find a virus causing it.
That day arrived in 1987. The laboratory for the job was no less than the research facility of the Chiron Corporation, a biotechnology company located directly across the bay from San Francisco. Equipped with the most advanced techniques, a research team started its search in 1982 by injecting blood from patients into chimpanzees. None of the monkeys contracted hepatitis, although subtle signs vaguely resembling infection or reddening did appear. For the next step, the scientists probed liver tissue for a virus. None could be found. Growing desperate, the team fished even for the smallest print of a virus, finally coming across and greatly amplifying a small piece of genetic information, encoded in a molecule known as ribonucleic acid (RNA), that did not seem to belong in the host's genetic code. This fragment of presumably foreign RNA, the researchers assumed, must be the genetic information of some undetected virus. Whatever it was, liver tissue contains it only in barely detectable amounts. Only about half of all hepatitis C patients contain the rare foreign RNA. And in those who contain it, there is only one RNA molecule for every ten liver cells - hardly a plausible cause for disease.
The Chiron team used newly available technology to reconstruct pieces of the mystery virus. Now they could test patients for antibodies against this hypothetical virus and soon discovered that only a slight majority of hepatitis C patients had any evidence of these antibodies in their blood. Koch's first postulate, of course, demands that a truly harmful virus be found in huge quantities in every single patient. His second postulate requires that the virus particles be isolated and grown, although this supposed hepatitis virus has never been found intact. And the third postulate insists that newly infected animals, such as chimpanzees, should get the disease when injected with the virus. This hypothetical microbe fails all three tests. But Koch's standards were the furthest thing from the minds of the Chiron scientists when they announced in 1987 that they had finally found the "hepatitis C" virus...."
That day arrived in 1987. The laboratory for the job was no less than the research facility of the Chiron Corporation, a biotechnology company located directly across the bay from San Francisco. Equipped with the most advanced techniques, a research team started its search in 1982 by injecting blood from patients into chimpanzees. None of the monkeys contracted hepatitis, although subtle signs vaguely resembling infection or reddening did appear. For the next step, the scientists probed liver tissue for a virus. None could be found. Growing desperate, the team fished even for the smallest print of a virus, finally coming across and greatly amplifying a small piece of genetic information, encoded in a molecule known as ribonucleic acid (RNA), that did not seem to belong in the host's genetic code. This fragment of presumably foreign RNA, the researchers assumed, must be the genetic information of some undetected virus. Whatever it was, liver tissue contains it only in barely detectable amounts. Only about half of all hepatitis C patients contain the rare foreign RNA. And in those who contain it, there is only one RNA molecule for every ten liver cells - hardly a plausible cause for disease.
The Chiron team used newly available technology to reconstruct pieces of the mystery virus. Now they could test patients for antibodies against this hypothetical virus and soon discovered that only a slight majority of hepatitis C patients had any evidence of these antibodies in their blood. Koch's first postulate, of course, demands that a truly harmful virus be found in huge quantities in every single patient. His second postulate requires that the virus particles be isolated and grown, although this supposed hepatitis virus has never been found intact. And the third postulate insists that newly infected animals, such as chimpanzees, should get the disease when injected with the virus. This hypothetical microbe fails all three tests. But Koch's standards were the furthest thing from the minds of the Chiron scientists when they announced in 1987 that they had finally found the "hepatitis C" virus...."
Therefore, either steroid avoidance or maintaining low levels, coupled with a slow tapering of corticosteroids, may be beneficial to HCV-infected transplantation recipients
Evidence suggests that steroid boluses used to treat acute rejection are associated with an increase in HCV viral load and the severity of recurrence
http://www.ingentaconnect.com/content/bsc/nyas/2007/00001110/00000001/art00047;jsessionid=2knt9osgd5xwq.alexandra
http://www.ingentaconnect.com/content/bsc/nyas/2007/00001110/00000001/art00047;jsessionid=2knt9osgd5xwq.alexandra
Here is another one...steriods can affect tx drugs and guess what commerical poulty and meats are pumped up with?.....growth hormones(steriods)....id rather eat a dead skunk
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