Aa
Found this a disturbing arcticle...
Didn't want to alarm anyone by posting this on the other side, ... thoughts? comments?
(Feel like I'm going out on the limb a little posting this, but here goes...)
Hepatitis C and ocular surface disease.
Author: Jacobi,Christina
Add.Author / Arnd,Korn
Editor: Cursiefen,Friedrich E
Wenkel,Klaus
Jacobi,Claus
Kruse,Hartmut
Citation: Am J Ophthalmol. Volume: 144, Issue: 5, Date: 2007 Nov , Pages: 705-711
Year: 2007
Abstract: PURPOSE: To assess the frequency of changes in the ocular surface and the presence of hepatitis C virus (HCV) in tear samples of patients with chronic HCV infection. DESIGN: Prospective, nonrandomized, clinical, interdisciplinary, single-center study. METHODS: Seventy-one patients with previously untreated chronic HCV infection and a control group consisting of 66 patients without systemic HCV infection were enrolled in the trial. The patients with HCV infection were screened for ocular symptoms, visual acuity, and ocular changes. Tear production was measured by the Jones test. Conjunctival impression cytologic analysis was performed. The presence of HCV ribonucleic acid (RNA) in tear and blood samples was determined by quantitative polymerase chain reaction. RESULTS: On examination, systemic HCV infection was present for a median of 30 months. Fifty percent of all HCV patients showed a decrease in tear production measured by the Jones test. Apart from epithelial changes related to dry eye syndrome in 12 patients, two patients presented mild peripheral corneal thinning. Polymerase chain reaction analysis detected HCV RNA in five (10%) of 52 tear samples. HCV RNA levels in tear samples (mean, 1.0 x 10(4) copies/ml) were considerably lower than in blood samples (mean, 5.3 x 10(5) copies/ml). CONCLUSIONS: Dry eye syndrome is the most frequently observed ocular feature in HCV infection.
Patients with HCV infection (age range, 21 to 60 years) compared with the controls had a significant lower tear production (P = .05). The presence of HCV RNA in 10% of tear samples emphasizes the potential risk of viral transmission through tears.
Certainly not a large sample of patients (71) but the claim that RNA copies were higher in tears than in blood brings a flood of questions to my mind.
(Feel like I'm going out on the limb a little posting this, but here goes...)
Hepatitis C and ocular surface disease.
Author: Jacobi,Christina
Add.Author / Arnd,Korn
Editor: Cursiefen,Friedrich E
Wenkel,Klaus
Jacobi,Claus
Kruse,Hartmut
Citation: Am J Ophthalmol. Volume: 144, Issue: 5, Date: 2007 Nov , Pages: 705-711
Year: 2007
Abstract: PURPOSE: To assess the frequency of changes in the ocular surface and the presence of hepatitis C virus (HCV) in tear samples of patients with chronic HCV infection. DESIGN: Prospective, nonrandomized, clinical, interdisciplinary, single-center study. METHODS: Seventy-one patients with previously untreated chronic HCV infection and a control group consisting of 66 patients without systemic HCV infection were enrolled in the trial. The patients with HCV infection were screened for ocular symptoms, visual acuity, and ocular changes. Tear production was measured by the Jones test. Conjunctival impression cytologic analysis was performed. The presence of HCV ribonucleic acid (RNA) in tear and blood samples was determined by quantitative polymerase chain reaction. RESULTS: On examination, systemic HCV infection was present for a median of 30 months. Fifty percent of all HCV patients showed a decrease in tear production measured by the Jones test. Apart from epithelial changes related to dry eye syndrome in 12 patients, two patients presented mild peripheral corneal thinning. Polymerase chain reaction analysis detected HCV RNA in five (10%) of 52 tear samples. HCV RNA levels in tear samples (mean, 1.0 x 10(4) copies/ml) were considerably lower than in blood samples (mean, 5.3 x 10(5) copies/ml). CONCLUSIONS: Dry eye syndrome is the most frequently observed ocular feature in HCV infection.
Patients with HCV infection (age range, 21 to 60 years) compared with the controls had a significant lower tear production (P = .05). The presence of HCV RNA in 10% of tear samples emphasizes the potential risk of viral transmission through tears.
Certainly not a large sample of patients (71) but the claim that RNA copies were higher in tears than in blood brings a flood of questions to my mind.
I have tear drops in my blood, seriously. it made it coagulate, very thick.
It is the rescue drugs. My eyes get dry also
It is the rescue drugs. My eyes get dry also
:)
"Cry into my veins"... sounds like a title to a Guns N Roses song or something lol.
"Cry into my veins"... sounds like a title to a Guns N Roses song or something lol.
If you dont cry into anyones veins there wont be a problem.
I got dry eyes though so I dont have any tears, so i cant cry into anyones veins.
CS
I got dry eyes though so I dont have any tears, so i cant cry into anyones veins.
CS
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