Aa
Tallblonde
hi, hate to be so public in telling you this, but I have no other way really.....you and I have always been in "somewhat" the same boat in terms of how we've been dealing with our disease, anyway, I had a fibroscan today, like a few other members here....and I think it would be great for you to get one too, great relief off my mind and there are no big gauge needles to deal with! You probably know it's a scanning procedure, that gives you images of the entire liver...anyway, don't know if you do, but if so, Ina has my info and I could get you in touch with the good doctor, it's here in Los Angeles in a fairly beutiful setting...hope youre well...
Just taking a chance, don't even know if youre still reading...maybe so...
Just taking a chance, don't even know if youre still reading...maybe so...
The only studies I see so far are studies for geno 1 slow responders...48 weeks versus 72 weeks...referenced 10-12...and all they said was 4 randomised studies were done.
Geno 2&3 has study references, that's tomorrow, or later.
Willing...(Abb 2 should have said Abb 2 and 3)
Abb stands for picture.
Ina
Geno 2&3 has study references, that's tomorrow, or later.
Willing...(Abb 2 should have said Abb 2 and 3)
Abb stands for picture.
Ina
Now that my metabolic syndrome has worsened from the treatment drugs, would it be an imposition if you baked up a lower carb donut? I'll bring the coffee and Ina can just bring herself for being so kind to translate from the motherland. Speaking of tea, have you tried "Roobios". Nice sweet flavor without caffeine. Not even technically a tea but from an African Bush. A blend goes under the name "Red Bush Tea" at Starbucks. Tastes good straight or with milk or soy milk. I think first heard about Roobios here from TallBlonde and Rocker. Remember Rocker? Do miss that guy. Speaking of which -- and back to the real teas - a recent study suggested that putting milk in tea undues all the good stuff teas do. Possibly why heart disease is less in Japan than England. You really make donuts? I'm impressed.
-- Jim
-- Jim
Ina: not that I know of. The neurologist ordered it as follow up when I noticed numbness in hands/feet and then I never went back to actually do the draw until your post today. If it wasn't for all the helpful reminders on this board (Susan about the teas, Jim about the bx 2nd opinion, Califa about the B12, you about the RA) I'd be in big trouble.
Jim: depends on what Ina reports back. If that Berg paper releases the results of a new large-population study with VL measured to <10, which it seems to, then VL in the 10-50 range will become predictive of outcome. Up to now, to the best of my knowledge there hasn't been any data on which to base interpretation of a VL < 50. Even with that new data, a VL in the 2-10 range will be uninformative until studies track the outcome of patients who manifest in that range. Then presumably it's on to the PBMC and real-time PCR techniques.. Basically my point is that a measurement is only meaningful when you can compare it with a distribution of outcomes (and BTW I'll make that a jelly-filled donut).
Jim: depends on what Ina reports back. If that Berg paper releases the results of a new large-population study with VL measured to <10, which it seems to, then VL in the 10-50 range will become predictive of outcome. Up to now, to the best of my knowledge there hasn't been any data on which to base interpretation of a VL < 50. Even with that new data, a VL in the 2-10 range will be uninformative until studies track the outcome of patients who manifest in that range. Then presumably it's on to the PBMC and real-time PCR techniques.. Basically my point is that a measurement is only meaningful when you can compare it with a distribution of outcomes (and BTW I'll make that a jelly-filled donut).
Are you then conceding their importance at least during treatment? As to EOT, I suppose the importance lies in identifying those that are in the TMA positive subset of PCR negatives. Since this entire subset will relapse -- at worst administering an EOT TMA will not keep false hope alive any longer than it should; and at best some action might be taken sooner such as re-treatment, a follow-up biopsy, selling the house, etc. That's quite a long article, so unless Ina focuses on some very short sections, I doubt we will get much further on that unless someone wants to go through the computer translation process.
-- JIm
-- JIm
Just got in after a very long day at work. I'm ready for bed, but will respond tomorrow to your post. Please check back later...
uh - I'm starting to feel like one of those polar bears in the North Atlantic - it really is just a (short) matter of time till there *are* large scale studies against which to interpret the results of high-sensitivity VL tests (and if this article is reporting a large new data set collected at a sensitivity of 10 there's bound to be an English version somewhere). However, I'm willing to bet a donut you won't find any treatment recommendations hinging on the importance of a high-sensitivity test at EOT (even if this shows you in fact never cleared) or post-tx...
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