Hello Everyone,
Does anyone have any recent data or know of any new studies that attempt to answer the question of whether acyclovir or valacyclovir therapy delay seroconversion? In past posts, Dr. HHH stated that it is unlikely that antivirals delay seroconversion while a more recent post by Dr. EWH states that more recent data suggests antiviral therapy can delay seroconversion. Can some shed some light on this?
Below is my timeline of events.
8/21 possible exposure - unprotected sex with woman ( i do not know if she is +/- for HSV 2)
10/1 pain, redness, warm sensation on left side of penis
10/7 6 week post exposure Herpeselect type specific I negative, II negative
10/9 Started valacyclvir 1g x 10 days. Pain subsided within one hour of taking first dose. Switch to acyclovir 250mg twice a day because valacyclovir gave me an upset stomach.
11/24 stopped acyclovir
11/9 negative herpeselect 9 wks post exposure
11/22 negative herpeselect 11 wks post exposure
12/13 negative herpeselect 13 wks post exposure
12/28 negavtive herpeselect 18 wks post exposure
1/6 had pain, redness along left side of penis. I panicked and took 1g valtrex pill. Again pain went away within 1.5 hours
1/11 negative herpeselect 20 wks post exposure
Initially I thought antivirals did not affect seroconversion. Now after reading Dr. EWH response I'm not so sure. Sorry I can't find the exact post. Would love to hear any relevant information from readers and docs.
Thanks!