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Herpes Questions

Sorry, I have a long list of questions to ask regarding Herpes genital HSV 1.

(a) According to Dr. HHH in his forum, 40% of GHSV 1 - no recurrence and 50% of GHSV 1 will have 1-2 recurrences in the first 1-2 years, then none. The question is that total of 90% is for those taking anti-viral medication or without any medication at all?

(b) According to Dr. HHH, GHSV 1 is almost never transmitted to anyone either orally or genitally. This sentence is based on whether the carrier is taking anti-viral medication or not? The word 'almost' is based on what percentage?

(c) If age grows older say up to 50 or 55 year old above, will GHSV 1 recurs due to weaker immune system as age grow older? Or there will be no more recurrence at all since after so many years of absent of recurrence?

(d) Currently a vaccine call Herpevac is on trial and I understand that the vaccine is only for woman and is only for HSV 2. Why there isn't any vaccine currently on trial for HSV 1 as I have read in the news that HSV 1 is far more serious than HSV 2 as more and more GHSV is due to HSV 1.

(e) Can Herpevac use to prevent HSV 1 since HSV 1 and HSV 2 sharing 50% of the same DNA? If yes, Herpevac can help to prevent how many percent of HSV 1 transmission?

(f) Herpevac has been on trial for so many years. What is the likely date of approval for the vaccine to be used by the public?

(g) Is there any website showing mild herpes pictures? I have seen plenty of website, there only show serious herpes pictures. Please let me have the name of the website.

Thanks
10 Responses
101028 tn?1419606604
(a) According to Dr. HHH in his forum, 40% of GHSV 1 - no recurrence and 50% of GHSV 1 will have 1-2 recurrences in the first 1-2 years, then none. The question is that total of 90% is for those taking anti-viral medication or without any medication at all?

episodic therapy only - treating each ob's as it occurs.

(b) According to Dr. HHH, GHSV 1 is almost never transmitted to anyone either orally or genitally. This sentence is based on whether the carrier is taking anti-viral medication or not? The word 'almost' is based on what percentage?

we don't have percentages for that. I also don't go quite with the  almost never though - I go with it's not likely to transmit but it can. I feel HHH under estimates this and there is limited research to back that underestimation however currently the research hasn't clarified if it's genital hsv1 transmission or hsv1 oral transmission of the virus from folks contracting hsv1 orally too when they contract it genitally and not realizing it. hsv1 sheds more from the oral area to the genital area.  

(c) If age grows older say up to 50 or 55 year old above, will GHSV 1 recurs due to weaker immune system as age grow older? Or there will be no more recurrence at all since after so many years of absent of recurrence?

We don't have data on this to give a good answer.  I know some folks with hsv1 genitally who go a good long time in between ob's and we don't pick up on that in the studies. for instance a friend of mine went 17 years in between obvious genital hsv1 recurrences. Those kinds of things don't reflect in a 6 month study.  No documentation of ob's increasing in old age though if that is the gist of the question.  

(d) Currently a vaccine call Herpevac is on trial and I understand that the vaccine is only for woman and is only for HSV 2. Why there isn't any vaccine currently on trial for HSV 1 as I have read in the news that HSV 1 is far more serious than HSV 2 as more and more GHSV is due to HSV 1.

It's my understanding that it didn't protect for hsv1 like it did hsv2.  
Hsv2 is still the #1 cause of recurrences, hsv1 is fast becoming the #1 cause of initial ob's.  does that make sense?

(e) Can Herpevac use to prevent HSV 1 since HSV 1 and HSV 2 sharing 50% of the same DNA? If yes, Herpevac can help to prevent how many percent of HSV 1 transmission?

Study will be out within a year or two and we'll have better answers to that question.  

(f) Herpevac has been on trial for so many years. What is the likely date of approval for the vaccine to be used by the public?

I'd say 3 or 4 years probably if the phase 3 trials were found to be effective enough to get fda approval.  This vaccine has actually been in testing stages now for over 15 years I think.  

(g) Is there any website showing mild herpes pictures? I have seen plenty of website, there only show serious herpes pictures. Please let me have the name of the website.

Google images is the best thing to do.  Most online resources though are so severe that they are incredibly obvious so that you aren't sitting there doing a where's waldo type thing trying to find the herpes lesions.

grace

101028 tn?1419606604
(a) Is it possible that a husband contracted genital HSV 1 and never transmit the virus to wife throughout the entire lifespan. If yes, what is the percentage in the past history that husband is GHSV 1 and wife is not contracted. "Since the outbreak for genital HSV 1 is almost never recur (as per Dr. HHH's statement), thus no anti-viral medicine is required except in severe outbreak condition, I presumed".

Yes this is not only possible but probable.  we don't have % for this. No one studies discordant couples for longer than a year max in studies let alone for a lifetime.

(b) Is it possible to contract GHSV 1 from oral sex if there is no visible cold sore at the lip area? Could the virus is within the mouth or throat and not at lip area?

yes you can transmit it without obvious cold sores present.  

(c) Can GHSV 1 causes cervical cancer? If yes, what is the percentage of such case?

no

(d) According to Dr. HHH in his forum, asymptomatic shedding is uncommon for GHSV 1. What is the percentage refers to the word 'uncommon'?

3-5% is what most studies show with newly acquired hsv1 genital infections.  I've seen some studies report back with much less - depends on how they are doing it and for how long.

(e) With GHSV 1, how can the carrier uses a single piece of trowel for the entire body (from face to feet). Is there any procedure to avoid passing of virus to other parts of body? According to Mayflower, one of the advisor in this forum (I think so), she mentioned that trowel cannot be transmiited the virus, even her daugther is using the same trowel with her. How true is her statement?

This isn't an issue.  You aren't going to transmit hsv all over your body. The skin on most body parts is too thick. We don't advocate sharing towels , washcloths, toothbrushes or razors with anyone no matter what your herpes status is since very common germs are very easily transmitted thru sharing them. That said - I would not hesitate for a nanosecond to share a towel with any of my family members if in a bind just because of my herpes ( hope that makes sense ).  

(f) What is the symptom / feeling of Herpes Whitlow likes? How do we know the blister on our palm is herpes or not as most of the people get blisters in our palm in our everyday's life. It is not possible to culture a blister whenever we saw a blister, right?

Pretty much hurts like a sob from what I've been told.  it won't look like a regular blister you get from say raking the lawn or pushing the mower.  

grace
101028 tn?1419606604
Tom - I think you are going a bit far in all these questions at this point. if you suspect you have whitlow go and be seen and have it cultured.

grace
101028 tn?1419606604
We don't know if hpv actually is really gone or just so dormant that we don't detect it with the means we have at our disposal at this time.  We just know that within 2 years -  in 91% of those infected with hpv  we can not longer detect it.

There are different brands of pap tests. Some automatically test for high risk hpv, some test for high risk and low risk, others don't test for hpv at all.  

You can have a perfectly normal pap and still test + for hpv.  It usually takes years until a hpv infection is able to start causing abnormalities on pap tests ( there are a few strains that are the exception ).

grace
101028 tn?1419606604
They try to only give the hpv vaccines to females who have no known history of hpv.  Ideally they would be given when they are young and not sexually active yet for maximum immune system response as well as being effective before hpv is contracted.  A woman with a history of hpv supposedly isn't to be given the vaccine but I think most practioners are just because of the cross protection against other types of hpv it provides. It certainly doesn't hurt to give the vaccine to someone already infected that's for sure.  Currently the vaccines for hpv aren't approved to be given to someone who is known to have hpv - I'm not familar with the research to accurately quote to you info on when it's given to women with known high risk hpv infections.  

we don't really have stats on the risk of contracting hpv either orally or genitally.  1 out of every 3 sexually active adults has had it at some point or another.  We do know that putting the condom on when the clothes come off and not waiting until actual penetration can reduce the chance of transmitting hpv by 90%.

The 91% stat is all symptoms are gone and with the testing measures we currently have there is no hpv able to be detected either in the blood, urine or skin.

There is a seperate hpv forum here on medhelp - if you have more questions about hpv you might want to ask them there.  

grace



101028 tn?1419606604
also each of the hpv vaccines have terrific websites to check out too for more reading :)

grace
Avatar universal
Hi Grace,

My partner and I finally got a prescription for Valtrex from her doctor after he consulted with one of his associates(yes, he was not very knowledgeable to say the least). Before we got a chance to pick up the medication she had her first outbreak ever, which was rather shocking to say the least. We had sex the day prior to the outbreak, protected, and I wanted to know if there is shedding prior to an outbreak. Lastly, with the valtrex, if we eventually decide to go without protection, for reproductive purposes, would there still be the same risk of transmission. It says on some sites that condoms are really inefective against herpes transmission. Thanks
207091 tn?1337713093
COMMUNITY LEADER
Hi there -

Grace is out of town, and I must have missed this one in the shuffle.

Your VDRL is probably accurate at 31 days.  You never mention what your risk was, and why all this was brought up, so I can't say more than that.  It can take a bit longer for some to test positive for syphilis, but I don't even know if the test was needed.

Your hsv2 test is maybe 50% accurate, and the urine tests (I'm assuming they are for gonorrhea, chlamydia, etc), are accurate.

Your hsv1 test is probably 75% accurate, and your HIV test is about 95% accurate.

Again, I don't know your risk factors, etc., to know why you are going through this testing, etc.  I can't really say if you need further testing or not.  Did you have symptoms?  

Aj

207091 tn?1337713093
COMMUNITY LEADER
All this over type 1?  Your type 1 is probably an oral infection you've had for years and years, and is nothing at all to freak out about.  Well over half of the population has it.

Whitlow, from what I understand from people who have it, is PAINFUL.  Every person I know who has it, and there are a few, talk about how painful it is.  No one has ever said it wasn't painful, and everything I've read on it says its PAINFUL.  Unless you had a break in the skin on your hand where you have this blister, you can't get herpes on your hand anyway.

I don't know anything about an HPV DNA test.  There are no commercial HPV tests for men available.  

Seriously, and I say this with kindness, have you ever seen a doctor or therapist for anxiety or obsessive compulsive disorder?  This reaction is over the top and not normal for an hsv1 infection.

Aj



207091 tn?1337713093
COMMUNITY LEADER
Are you Steve663?

Aj
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