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Latest 10 progress on Herpes Cure
The Top-Ten upcoming new herpes drugs
The acyclovir family of herpes antivirals has been around in one form or another for the last 20 years. It's high time some progress was made, especially given that the ASHA says 50% of women in the USA will have genital herpes by 2025.
Here is a shortlist of the most likely new treatments to become available soon, in order of how close they are to market, number 1 being the closest to market. Make your own additions to, or comments on, the list.
Here's the countdown:
1. Herpevac
Although there's a mysterious quiet at GSK recently, Herpevac is apparently finishing up Phase III trials. It won't be of any use to anyone who already has herpes, but it's the first real attempt to bring a vaccine to market. Rumor has it that the vaccine is around 75% effective in women who don't already carry either herpes type.
2. Nanobio NB-001
Ok, so it's a cream, but it's no ordinary cream. Nanobio's NB-001 uses extremely small particles called nanodroplets, which penetrate the skin and attack the virus directly. It makes Zovirax look antiquated.
3. Starpharma Vivagel
A new condom-coating that might also come as a cream. Recent trials on animals have shown it is between 85 and 100 per cent effective at blocking HIV and Herpes transmission.
4. Astellas ASP-2151
The most promising of the long-awaited Helicase Primase Inhibitors (HPI) drugs. And I really mean long-awaited. This is like super-acyclovir, and there's been some speculation that it could inhibit the virus so effectively that asymptomatic shedding may not be an issue.
5. Immunovex HSV2
A genetically-modified live herpes virus that won't be able to cause any symptoms, but will guard against infection from the symptomatic type. Immunovex plan to hold Phase I trials this year. The theory behind the vaccine is solid, and the animal trials were successful.
6. ACAM-529
Harvard's modified herpes virus can't multiply or infect cells. Two important genes are deleted to take the bite out of herpes. Scientists hope that this vaccine will prepare the body should it be attacked by the real virus. It may also help symptomatic people already carrying herpes. Acambis are investigating the technology, and Harvard continues to research the treatment. You can donate to their research here.
7. University of Florida vaccine
This is pretty much the Holy Grail of herpes vaccines, with the potential to actually cure people of the virus. The University proposes a vaccine that actually cuts into the structure of the virus, damaging it so significantly that it is eaten up by the body.
8. Bill Halford's vaccine
Great ideas from this inspiring maverick researcher. Halford plans to use a live virus to stimulate constant inoculation against nastier strains. By deleting an important part of the herpes virus, Halford can produce a new type of herpes virus that does infect you, but won't produce visible signs. If everyone's asymptomatic then the virus will be soon forgotten.
9. Bavituximab
This novel drug could combat a range of viruses, from Herpes to HIV. Bavituximab is an antiviral that could be to viruses what antibiotics are to bacteria.
10. Vironova's VN-180
An interesting broad-spectrum antiviral with a range of possible applications, like Bavituximab. It looks impressive, but is in the very early stages of development.
The acyclovir family of herpes antivirals has been around in one form or another for the last 20 years. It's high time some progress was made, especially given that the ASHA says 50% of women in the USA will have genital herpes by 2025.
Here is a shortlist of the most likely new treatments to become available soon, in order of how close they are to market, number 1 being the closest to market. Make your own additions to, or comments on, the list.
Here's the countdown:
1. Herpevac
Although there's a mysterious quiet at GSK recently, Herpevac is apparently finishing up Phase III trials. It won't be of any use to anyone who already has herpes, but it's the first real attempt to bring a vaccine to market. Rumor has it that the vaccine is around 75% effective in women who don't already carry either herpes type.
2. Nanobio NB-001
Ok, so it's a cream, but it's no ordinary cream. Nanobio's NB-001 uses extremely small particles called nanodroplets, which penetrate the skin and attack the virus directly. It makes Zovirax look antiquated.
3. Starpharma Vivagel
A new condom-coating that might also come as a cream. Recent trials on animals have shown it is between 85 and 100 per cent effective at blocking HIV and Herpes transmission.
4. Astellas ASP-2151
The most promising of the long-awaited Helicase Primase Inhibitors (HPI) drugs. And I really mean long-awaited. This is like super-acyclovir, and there's been some speculation that it could inhibit the virus so effectively that asymptomatic shedding may not be an issue.
5. Immunovex HSV2
A genetically-modified live herpes virus that won't be able to cause any symptoms, but will guard against infection from the symptomatic type. Immunovex plan to hold Phase I trials this year. The theory behind the vaccine is solid, and the animal trials were successful.
6. ACAM-529
Harvard's modified herpes virus can't multiply or infect cells. Two important genes are deleted to take the bite out of herpes. Scientists hope that this vaccine will prepare the body should it be attacked by the real virus. It may also help symptomatic people already carrying herpes. Acambis are investigating the technology, and Harvard continues to research the treatment. You can donate to their research here.
7. University of Florida vaccine
This is pretty much the Holy Grail of herpes vaccines, with the potential to actually cure people of the virus. The University proposes a vaccine that actually cuts into the structure of the virus, damaging it so significantly that it is eaten up by the body.
8. Bill Halford's vaccine
Great ideas from this inspiring maverick researcher. Halford plans to use a live virus to stimulate constant inoculation against nastier strains. By deleting an important part of the herpes virus, Halford can produce a new type of herpes virus that does infect you, but won't produce visible signs. If everyone's asymptomatic then the virus will be soon forgotten.
9. Bavituximab
This novel drug could combat a range of viruses, from Herpes to HIV. Bavituximab is an antiviral that could be to viruses what antibiotics are to bacteria.
10. Vironova's VN-180
An interesting broad-spectrum antiviral with a range of possible applications, like Bavituximab. It looks impressive, but is in the very early stages of development.
Hi everyone -
We just want to make sure that everyone understands that there is nothing that will cure herpes. If you'd like to try garlic to see if it works for you, please do, but please do not assume that it will cure you, or work to reduce transmission to another person.
Thanks,
Emily
We just want to make sure that everyone understands that there is nothing that will cure herpes. If you'd like to try garlic to see if it works for you, please do, but please do not assume that it will cure you, or work to reduce transmission to another person.
Thanks,
Emily
1 Comments
Admedus and Rational vaccines are the closest for a functioning cure. Both are doing very well! Scientist are getting closer this is not the 80's technology should be smarter by now to at least get a real vaccine to market in the next 5 years. People should not have to keep suffering from this crap of a virus especially when diagnosis this garbage sucks and is all over the place. You should not have to do 8 tests to feel comfortable with an answer.scientists suck when it comes to herpes which don't seam like that complex of a virus. They know how it works now it's time to crack the code!
we should all google in Pubmed:
http://www.ncbi.nlm.nih.gov
as there are the latest findings about medicine..
and share our results here...
but it seems that including garlic in our diets could improve the condition...
but as I recently knew this I need to search more this..
One or 2 pieces of crushed garlic a day will help and having a kind of healthy life.
http://www.ncbi.nlm.nih.gov
as there are the latest findings about medicine..
and share our results here...
but it seems that including garlic in our diets could improve the condition...
but as I recently knew this I need to search more this..
One or 2 pieces of crushed garlic a day will help and having a kind of healthy life.
Have an Answer?
You are reading content posted in the Herpes Community
Herpes spreads by oral, vaginal and anal sex.
Herpes sores blister, then burst, scab and heal.
STIs are the most common cause of genital sores.
Millions of people are diagnosed with STDs in the U.S. each year.
STDs can't be transmitted by casual contact, like hugging or touching.
Syphilis is an STD that is transmitted by oral, genital and anal sex.
