Aa
Aa
A
A
A
Close
Avatar universal

My timeline doesnt make sense?

My last partner prior to testing positive was in September 2009. In Oct 09- got back w ex bf.
I tested  negative for HSV 2 in March of 2010- I had an HSV 1 and 2 Igg and igm type specific test and culture. hsv 1 was neg too.
July 2010 I found out my bf cheated on me and I developed a bump on my outter labia where the hair is.- i retested for hsv 1 and 2 igg and igm and was positive for hsv ii igg at 7.7.  the bump I developed I thought was a flee bite.

october- I tested >5.00 hsv ii igg positive

October 2010- now ex bf got tested- he is negatrive for HSV II but positive for HSV I igg tests

October 2010- I was tested again-  HSV II IGG positive.-4.2

December 2010- tested positive herpeselect >5.00 HSV II IGG

1)Is is possible that it would take ex that long to seroconvert?.. it would have been from at least July through October? How can it not show up in his blood?   2) I would think maybe guy #1 infected me but it was literally 6 months from exposure to testing.... guy 1 subsequently said he " was clean as a whistle".. i think he was tested when his new gf got pregnant. 3) I almost wish guy #2 would be positive for hsv II or that he had an IGm test that wasnt reliable, but thats just not it.  So therefore, its hard for me to put this to rest. 4) I read a post Terri Warren commented on that indicated that there are some instances that some people bc of a substance in their blood, they test positive.  Is there anything in my blood that can be mistakingly making these test positive? 5) by the way- guy #2 has "outbreaks" ..and is convinced he has it even though he tested negative. He does not want to get re-tested bc of  $$$ and he is fine with having it, even though he is negative. 6) Is there a way I have HSV I and not HSV II? 7) Im nervous that I have another virus that is similar to this one and its making these test positive. Please help me make sense of this. thanks. I havent had noticable outbreaks
10 Responses
Sort by: Helpful Oldest Newest
55646 tn?1263660809
I have asked the top experts in the field about why there are false positive results, and they honestly don't know.  Certainly people speculate, but we just don't know for certain.  Western blot is not used to screen for HIV, an ELISA method is.  

The reason we don't confirm all herpes diagnoses with western blot is because the studies have done, comparing high positive results on ELISA with herpes western blot results.  There is extremely high correlation between the two, just not the same with low positives.

This will be my last post on this thread, thanks.
Terri
Helpful - 0
Avatar universal
Ive seen a few posts relating to hsv 2 results being false positive because of autoimmune diseases. There are so many studies regarding false positive in ELISA HIV testing due factors such autoimmune disease. From what I understand, ELISA testing is not used as a diagnosis for HIV. Why is it not the same HSV?  doesnt seem like ELISA for HSV should be a final result even for people >3.5 igg value.I understand the severity differences of the virus, but it doesnt seem like hsv 2 is researched enough compared to HIV, and justifiably so. I just think a lot more people think they have hsv 2 when they really dont, since it doesnt seem like the research for other interference factors. is there?
Helpful - 0
55646 tn?1263660809
No, I  haven't

Terri
Helpful - 0
Avatar universal
Hey Terri- I was wondering if you heard of any heterophilic antibody interference with HSV testing???    THanks again
Helpful - 0
55646 tn?1263660809
You can order the herpes testing toolkit at ashastd.org.  This will help you understand herpes testing better.  Yes, they all look for IgG but in slightly different ways.  The herpeselect and biokit look for a single marker of the antibody that is different for HSV 2 and HSV 1, but the western blot takes a much more comprehensive look at the antibody, looking for several markers, if you will.  

Terri
Helpful - 0
Avatar universal
Hi Terri- One last thing- Would you be able to explain the difference in the herpeselect vs biokit vs western blot as far as antibody response. From what I can understand the tests measure IGG antibody response differently, but how so?   Is there an article/ website you can refer me to for clarification or specifics?  Thanks.
Helpful - 0
55646 tn?1263660809
He could be a person who doesn't make antibody - there are a few.  Alternatively, it was too soon after his infection to test positive, or perhaps, he was diagnosed with herpes and has been taking medication that keeps his antibody development delayed.  None of this makes much sense, and I can see why you are frustrated.  

If you doubt your test results, I would recommend that you get a herpes western blot antibody test.  You can do this through Quest labs, the code is 34534.  You would have to get someone to order it for you, however.  But I really think you are infected.

I also can't believe they gave you test results, that is just amazing in the day of HIPAA security.  

I agree that the reaction to herpes is way overwrought in comparison to its medical severity.  Stigma is a hard thing to overcome, and I do what I can to quell the flames, but its difficult, for sure.

Terri
Helpful - 0
Avatar universal
I confirmed the test results of my ex bf (the one who probably infected me) with the walk-in doctor's office.. I cant even believe they told me the information they told me over the phone. I was informed that it was an IGG type specific test and that he was negative.. With that being said, and if in fact he (ex bf) is infact negative, what would be an explanation for that? I was thinking...

1) he doesnt make antibodies
2) his test was false negative
3) just maybe i have a similar antibody in my blood that is making my test positive? - the human body is exposed to billions of invaders...isn't somewhat possible that something can be altering my testing. Im sure Focus didnt perform research on every possible senario.   Im just such a skeptic..

I think it is great what you do. thanks for your help.  I just dont understand why everyone freaks out about herpes. I feel like Im missing something... I mean Im not dying right?? so what the hell is everyone's problem? Its like all the message boards and medhelp, and other sources is reinforcing everyone to freak out more than to just forget about it. I dont know, just my opinion.  Thanks Terri!

Helpful - 0
55646 tn?1263660809
1)Is is possible that it would take ex that long to seroconvert?.. it would have been from at least July through October? How can it not show up in his blood?

I"m not clear who is the ex boyfriend - the one you got back together with or the other one?  I'm thinking the one you got back together with.  Are you really clear that he is being honest with you?  That would be my worry.  Your test 6 months after your last enounter should be accurate  - you don't even know if this other partner was HSV 2 positive, right?
  2) I would think maybe guy #1 infected me but it was literally 6 months from exposure to testing.... guy 1 subsequently said he " was clean as a whistle".. i think he was tested when his new gf got pregnant.
You might double check to see if he was actually tested for herpes or not.  That would be important.
3) I almost wish guy #2 would be positive for hsv II or that he had an IGm test that wasnt reliable, but thats just not it.  So therefore, its hard for me to put this to rest
Again, do you really trust his statements, or did you see the test results?
. 4) I read a post Terri Warren commented on that indicated that there are some instances that some people bc of a substance in their blood, they test positive.  Is there anything in my blood that can be mistakingly making these test positive?
That pertained more to people who have a false low positive, not someone with high scores consistently, like yourself.
5) by the way- guy #2 has "outbreaks" ..and is convinced he has it even though he tested negative. He does not want to get re-tested bc of  $$$ and he is fine with having it, even though he is negative.
I think he's right, and I think he probably infected you.
6) Is there a way I have HSV I and not HSV II?
With HSV 2 index values that high, I believe you have HSV 2 infection.
7) Im nervous that I have another virus that is similar to this one and its making these test positive. Please help me make sense of this.
I doubt that.  I think you have HSV 2.  If you watch everything between waist and mid-thigh, I suspect you will notice an outbreak at some point.

Terri
Helpful - 0
Avatar universal
The reason I thought the bump in August 2010 was a flee bite is because my roomate's dog was flee infested. I had bites on my knees, ankles, toes,  wrists, fingers... also I had what I thought may have been athlete's foot, which i have never gotten in my life...Its like my body was out of whack. During this time I was extremely stressed: Moving, breaking up, legal trouble, debt, etc,.. i was a mess.. In fact I considered the idea of  maybe having shingles.. I would get random hives/ rashes .  I started supressive therapy in August 2010 (valtrex) .  The only symptoms I have gotten other than the "flee bite" is a small itchy patch of skin near my thumb I scratch it and 2 blisters formed...maybe just from friction... but Im  just have a feeling that this is not hsv 2.. and that is something in my blood that is making these test falsely positive.
Helpful - 0

You are reading content posted in the Herpes Forum

Popular Resources
Herpes spreads by oral, vaginal and anal sex.
Herpes sores blister, then burst, scab and heal.
STIs are the most common cause of genital sores.
Millions of people are diagnosed with STDs in the U.S. each year.
STDs can't be transmitted by casual contact, like hugging or touching.
Syphilis is an STD that is transmitted by oral, genital and anal sex.