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Really depressed herpes 2 diagnosed

Four years ago I was diagnosed with genital 
warts. I had them frozen off to only return within a month or two. So I decided to try the prescription drug Aldara on the advice of a dermatologist after he tried applying some similar acting agent product in the office with limited results after 5 weekly visits. Within 1 week of treatment my genitals became extremely sensitive and red, I also experienced  herpes like outbreaks on my lips and a general feeling of tiredness and malaise.  Three weeks into the therapy I developed two large sores on my scrotum. After four weeks I stopped using the mess and went to see the dermatologist. His initial thought was the sores were related to a reaction to aldara. But did a culture on the sore and ordered a blood test for herpes. I felt relieved yesterday when the culture came back negative. Then today ..The worst news possible. My herpes 2 test came back positive.  2.53 was the score and it was done by quest labs. At this point that is all I know. The sores mostly healed at this poi t a week later. Honestly I now feel like a virus center and I am really depressed about my future. Especially Considering I just broke off a 4 year relationship and just started dating again. So I guess a call to a psychiatrist is in order. Anyway my questions are what are the general chances of a false positive at that reading? Could aldara cause a false reading as a response mechanism? I read today aldara has issues with the onset of herpes . Can you add color to that? I feel like such a loser.
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55646 tn?1263660809
Your positive came in the low positive range.  Fifty percent of those who fall between 1.1 and 3.5 do NOT confirm as positive when tested with a better test.  It is very very common for Aldara to cause sores in the genital area, probably 80% of users have some skin abrasions.  Please work out a way to get a herpes western blot to confirm your HSV 2 antibody test.  It may well not be real.  You can either order a test kit directly from the University of Washington and have it drawn by your own doctor or we can order it for you at a local lab in your area through our clinic.  We are in Portland, OR. Westover Heights Clinic.

Terri
Helpful - 2
Avatar universal
what also would of been nice is if they would of looked at these peoplet tha had conflicting results  6 months later and see if they had any symptoms and make assumptions of what percentage may have new infections and see if conflicting results are likely positives or negatives in reality.
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Avatar universal
One concern I have in the report. I kind of like stats... so this bothered me. How that translates to 4% overall false positives as stated in the study I have no idea. if a third is in the low range and 44% to  65% are false. How do they report only 4.1% effected.
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Avatar universal
Thank you for the reference study. I googled and read the report. I attached
the URL for anybody to read in similar circumstance as me .http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1276011

Highlights of my reading

1) From the study about a third of positives are in the low positive range 1.1 to 3.5.
2) Actually 65%  of the low positives could not be confirmed by both BioKit and WB and only 44% were confirmed by one of two.
3) If you are infected with Herpes 1 already, your false positive potential likely increases significantly.
4)If you are of African descent the HerpesSelect results maybe false due to unknown reasons. (I am not, but wished I was at that moment).

Considering 1 in 4 Americans are infected with Herpes2 ( I READ That Singles older then 40 the rate is more like 1 in 2 and higher for women an astounding 70%) the chances I have it or no higher then the general population my age who are single.

I will get both confirming tests done to enable me to help me figure it all out. Kind of scared to at this point, since a positive result will be emotionally draining. But I certainly have a better outlook then I had a few days ago.
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Avatar universal
can you tell me what percentage of herpes select scores wind up in the 1.1 to 3.5 range?
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Avatar universal
that isn't what you wrote in the article. Please read it.
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55646 tn?1263660809
We are talking a bit of apples and oranges here.  The sensitivity of the ELISA for HSV 2 is 97%, which means that is MISSES three cases out of 100.  

The low positive thing is different.  Of the people that test positive in the range from 1.1 to 3.5, half do not confirm with western blot (which makes them likely false positives).  The reference is in a article by Dr. Rhoda Morrow comparing western blot, ELISA, and Biokit.

Terri
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Avatar universal
thanks. . can you place a link?
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Avatar universal
Terri:

I am confused. I just read an article online titled Herpes Testing For Health Care Providers"  written by YOU that states the specificity of the Herpeselect test to be 97%. you go on to say that translates into 3 out of 100 false positives and effecting the 1-3.5 score more often then higher scores. So how do you now figure it to be 50% of that sub group?
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55646 tn?1263660809
5032266678
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Avatar universal
Plwase pass me the phone number to begin the process.
Helpful - 0
55646 tn?1263660809
You need to contact the clinic and set up a phone appointment to become an official patient of the clinic.

Terri
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Avatar universal
Ok. Let's do it. What do I need to do to start the process to work through your clinic for Western blot test?
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Avatar universal
Unprotected with both girlfriends and condom was used with one night stands.
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Avatar universal
Last facts. I am straight male. Tested in September for standard std's (herpes not one of them) and all negative results. Last test for herpes was back in late 2009 and was negative for herpes 2 and positive for hsv 1 ( infrequent cold sores since childhood) . Monogamous relationship for 3 plus years since test. Then had a breakup whereby had two one night stands and since been with a new girlfriend for 4 months.
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Avatar universal
Your offices are in nyc? How do I make an appointment to consult with you in your offices?
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Avatar universal
Last question what are the statistical odds of passing herpes 2 orally to a non infected partner without using a condom? Is it highly unusual or somewhat dangerous or outright dangerous?
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Avatar universal
Also please next steps I should take. I was put on 4 day 2 supply of Acklivor (misspelled I know ). Should I begin daily therapy now if I am sexually active?
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