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treatments for poor kidney function

      Our dog has been on metacam for months and this last week started injections twice a week of                for his hips. Now the vet gave us asodyl and told us to give him a capsule three times a day.  This is for his kidneys. After the first capsule, the next day he had diarhea and dry heaving. He passed a little bit of red blood after straining several times to continue to evacuate. He was shivering afterwards, something that he seems to be doing more of lately. I am not sure if the azodyl caused this. The vet wasn't sure either.
       I was distressed after just paying $40  for the bottle of 60 azodyl capsules, when I read your comments about Azodyl not being proven to do anything for the kidneys. Is this just because it has not had a formal labratory study done or is it your personal observation that it does not work?
      I also have seen Tripsy on line. Is this the same stuff as azodyl?  Does Tripsy work?
1 Responses
234713 tn?1283530259
Hello, I am very sorry about your dog!

Your question is similar to the previous question about feline renal disease and is pertinent to your dog's condition.

Shivering is a bad sign that is linked to kidney failure, unfortunately.

Azodyl can cause digestive disturbances if introduced too quickly, in some cases.  

Azodyl is supposed to help the digestive system remove toxins that can no longer be filtered by the kidneys.  The theory is sound.  

Substitutes for Azodyl include: Pre and Probiotics such as acidophilus, bifida factors, FOS, and others plus beet fiber.  Both are available at health food stores or online.  They are both available as powder.  Begin with a very small amount ¼ teaspoon of each and gradually increase to 1 tablespoon on food twice daily.  Even higher doses can be used as long as they do not upset your dogs digestion.  Dosing is monitored by the consistency of your dog’s stool.  Once the stool becomes loose go back to the dose prior to the loose stool.

Daily Sub-Cutaneous Fluid therapy is very important and can be performed at your vet's office, or can be given at home (your vet or veterinary nurse/technician can instruct you how to perform this). Give 200 to 300  milliliters daily of Lactated Ringers Solution daily, if possible.

Give the Chinese Herbal Formula for kidney disease: Rehmannia 8 (Jin Gui Shen Qi Wan) at a full human adult dose twice to three times daily.  This is a common herbal formula and you may be able to find one specifically for pets online.

Have urine samples checked frequently and treat any urinary tract infection.

Give a glucosamine/chondroitin supplement,  this will help bladder and kidneys as well as joints.

An Ace Inhibitor medication, such as enalapril can be a helpful adjunct, since it helps to aid in perfusion of the kidneys.  This is available at your veterinarian's

B-complex vitamins, vitamin C and D.  Use an over the counter vitamin formula at ½ human adult dose.  Vitamin D is extremely important because when kidney function is lost vitamin D is no longer produced in adequate quantities.  A blood test is available to check vitamin D levels.

A low protein diet is no longer always advocated for kidney disease.  

Veterinary Acupuncture would be very beneficial.  It could be used for the hip dysphasia and to benefit kidneys.  It would also help reduce the dependence on Metacam, and increase your dog’s quality of life.  Rehmannia 8 is available at most veterinary acupuncturists.
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