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Avatar universal

Please help I am LOST

Hi,

Here is my story. I would be very grateful for any input.

Day 0:  Unprotected received fellatio and protect vaginal sex with an escort. Mutual masturbation and vaginal secretion probably in contact with my penis from hands
Day 1: frequent urination and burning tip of the penis for 2 days. I do not urinate frequently anymore
Day 4: intermittent discomfort in the left testicular lasting for 8 weeks as well as discomfort in the upper legs area.
Day 10: a rash, probably a Maculopapular very itchy rash lasting for 6 days. (I had gone to the beach the same day and I started to feel itchy while in the water. I had taken also the day before 1,5 mg of Zithromax)
11 week: White furry tongue (neither fungi or bacterial infection) with a fever of 37,2 Celsius lasting for a week. White tongue persisting until now (3 months) as well as a loss of appetite and weight loss in the legs area. (I had gone to the dentist on the 8th week for a root canal treatment and was on antibiotics Dalacin C 300 for 8 days)
22 weeks: hair loss, mainly from my eyebrows and hair on my torso and stomach. Lasting till now (week 26)
As at today, I still have a white tongue, a loss of appetite and hair loss issues.
I have made STDs check and 7 HIV 1&2 tests all negative. My blood picture is normal. I have just noticed that my WBC and lymphocytes fluctuate within the normal range. I have also done a CD4 CD8 count and they were within the normal range.

What kind of infection could I have caught?
I have come across this new HIV like disease:  

http://edition.cnn.com/2012/08/23/health/adult-onset-immunodeficiency-syndrome
https://sites.google.com/site/newhivaidslikeviruschina/home  

Should I be worried about this disease? Should I do an interferon-gamma (IFN-gamma) and a  quantative immunoglobin tests?
Thank you.
50 Responses
1415174 tn?1453246703
COMMUNITY LEADER
You would probably get a better answer on the STD site but the white tongue is probably a yeast. Did you say all STD tests were normal or just the HIV test? If not it could be Chlamydia or Gonorrhoea, The immunoglobulin test would just check your immune status. It would be better to figure out what you have. I don't know about the weight loss in the leg area. You may have some type of hormone deficiency or something like that because of the hair loss or perhaps a fungus? Is there anything on the area of hair loss that looks like a discoloration of skin? Otherswise, I don't know. It sounds somewhat like you need an endocrinologist. what does your doctor say?
Avatar universal
Many thanks for your answer.

All my STD tests were negative including the 6 HIV  Elisa tests and one HIV Western Blot test.

immunoglobulin would tell me if I have an infection or something? it is relevant no?

All the doctors to whom I went to say I have nothing. I went today to a dermatologist who said I have  seborrheic dermatitis, he prescribed a special shampoo to use 3 times a week. Will this also help hair that is easily falling from my stomach and torso? don't think so, I feel like doctors do not listen

But until now i cannot find an explanation to my white tongue and loss of appetite which came together.

3 weeks ago a parasite called entamoeba histolytica was found in my stools. I took medication for 4 days and I will do another stool analysis tomorrow to check if it is gone.

I was a healthy person and never had health issues. I do not know what is happening.

What do you think about the link I have provided?
1415174 tn?1453246703
COMMUNITY LEADER
Ok, now I understand things a little more. So no the immunoglobulin test won't tell you if you have an infection. It will tell you if your immune system is working ok. Some diseases can make your immune system not work properly but that is not what I think is going on. So, I have seborrhic dermatitis too and it doesn't make my hair fall out, it gave me some danderuff and a little itchy scalp. It is pretty common to get that. But hypothyroidism may make your hair fall out and some other hormonal problems. I have hypothyroidism too. You may want to get your TSH (thyroid stimulating hormone) checked. If it is too high that means you don't make enough of it so then you would be hypothyroid and they would give you synthroid a thyroid hormone. A lot of people have this. I was normal all my life and just became hypothyroid this year.  It causes fatigue as well. The white tongue is probably a yeast from taking the antibiotic or from a lowered immune system. Having E. hystolytica will make you loose your appetite, cause diarrhea, and sometimes blood in the stool.  It can be serious and i'm glad they caught it. Have you been out of the country? It may be affecting your immune system as well. You may have to take a couple of stool samples over time to make sure you get rid of the parasite. It is very important to follow up on that. I have to go back and read the link. I will do that now.
mkh9
1415174 tn?1453246703
COMMUNITY LEADER
So, I did look at the link and it is only so far, seen in Asians. Your symptoms don't really sound like that either way. The rash you had and other symptoms may have been due to an allergy to something in the ocean or due to skin contact with something on the person you had sex with. Also, it is possible the lab test had a false negative STD since your original symptoms were similar to an STD and the Azithro took care of it. If not the Azithro may have caused a yeast. I looked at your lab results and yes they do look good and the minor fluctuations are normal. The tongue photo doesn't really look like yeast it is not white enough. But maybe it is the photo. If you use a tongue scraper usually yeast will make your tongue bleed with normal scraping. It looks like cottage cheese and can hurt. It sounds like you were in contact with polluted water in any case because of the E. histolytica. I'm not sure about the weight loss in the leg area? Hard to say on that one. Did you measure your muscle before and after or does it just look like it? Is it substantially different than the other leg or are both the same? I'm not sure what else to suggest. I don't think you have this new form of HIV-like immune problem. But if you would feel better you can get your immune system checked. But I think it would show up some in your labs.
mkh9
1415174 tn?1453246703
COMMUNITY LEADER
p.s. the burning and frequent urination may have been a urinary tract infection rather than an STD. The Azithro would have taken care of most organisms for that too.
mkh9
Avatar universal
Many many thanks for your answer, it is greatly appreciated.

I have done a TSH, free T3 and free T4 test and they were within normal range.
I will do another stool analysis tomorrow, which would be 10 days after taking the medication which is in this link http://www.amoun.com/index2.php?page=shop.product_details&flypage=flypage.tpl&product_id=143&category_id=32&option=com_virtuemart&Itemid=59
do you think it is a good one?

with regard to the immunoglobolin test from what I understand it is useful for knowing if I have a parasite or infection or other diseases. http://labtestsonline.org/understanding/analytes/immunoglobulins/tab/test
But please correct me if I am wrong. I am also thinking of doing a CH50, C3, C4 test.
My CD4 was 850 and CD8 530

Why do you think my STD tests were false negative? which ones? well this frequent urination continued even after taking Zithromax. I had done like 5 urine tests, ureaplasma, mycoplasma in urine, Chalamydia x2 (blood), Gonnorhea and all were negative or normal. Maybe it was only stress I dont know :s. the burning sensation lasted for 1 or 2 days I think because of washing the tip of my penis with soap.

What I have on my tongue is not fungus, since I have done two oral swabs and no pathogens were found after 36 hours of incubation, I did a KOH test, and a last one for candida, all negative...
When I brush my tongue it doesn't go away and I have no bleeding.

Regarding my led weight loss, I think I lost more from my left leg (I am right footed and I used to play soccer often) but since 6 months I played like 5 times. I am well built as I used to go to the gym. I have lost also from the arms and waist. But the legs and waist were the first to be noticed.

I am worried about this new HIV like diseas because amongst its  symptoms, I have the white tongue, the loss of appetite, weight loss, mild skin peeling on the palm of the hands, hair loss...:s

In my last blood picture which I have done mid april I had 6000 WBC and 27% lymphocytes.

I look forward to reading you.
Avatar universal
I have done ANA, ESR, ASO, RPR, TPHA, MRSA,HSV 1&2, HPV - DNA by PCR, CMV, HBV, HCV, HAV (IgM (at 2 months), 7 HIV 1&2 and one HIV Western Blot, Liver and Kidney function tests, TSH, Free T3, Free T4, AFP, CEA, Ferritin, haemoglobin A1C, Testosterone total, Calcium, several urine analysis and culture, mycoplasma hominis, ureaplasma,, progesterone, zink and stool analysis. I also did HTLV test and waiting for the results

From all these tests I just found out about the parasite. and my progesterone and zink levels were high.
Progesterone 1.4  Nrange: 0.4-  1
Zink 160       Nrange: 46-150  
1415174 tn?1453246703
COMMUNITY LEADER
I have to read your last link, and I want to look up if the high progesterone in a man, will cause the hair loss and I think it is possible. I don't know the normal range of CD4 and 8 and the C3 and C4 I would have to look up.  I am a microbiologist so I didn't get some of this. Although believe me I took many classes in biochemistry, organic chemistry, and internship which included immunology, parasitology, mycology, general medical microbiology, etc. and I took hematology as part of my major but didn't work in hematology. I used to read my own slides, LOL.  I think you are worrying too much. As for the STD's and the urine culture and all that I think you have covered your bases. I think you are right it was probably irritation from the soap. You didn't have pain on urination, hard to urinate or a discharge? If not I wouldn't worry about that any more. The immunoglobulin level can be higher or lower due to your immune status such as if you are immune competent (can fight off an infection) or not. Also,  if you are fighting something off the values may change. But I will read your link. It is interesting. I also wouldn't worry about the 6000 WBC count as that is totally normal and fluctuates from 5000-9000 normally as you encounter bacteria, viruses etc. on a daily basis. Going to the dentist may make your WBC count go up for a day or two then it may go down. It isn't low normal it is normal. The 27% Lymphocytes is normal as well. You are fighting off having a pathogenic parasite. So, I would expect to have some variation in your values. The Eos (short for Eosinophils) can be high with a parasite but not always. I have seen them not change. You don't have severe wasting of the muscles do you? They just some what smaller? I have that too> I used to be a college and tournament tennis player and now I am weak and have small muscles especially on my non-dominant left side mostly due to a back injury. But I don't think that is abnormal if you had a change from doing a lot of sport to not much. Your tongue doesnt' look white to me. If it was yeast it would be very bright white. It looks yellowish to me and normal. I have the same color. Also, your yeast test was negative. You had no bleeding or pain on the tongue so it isn't yeast. I wouldn't worry about that. Your loss of appetite is most likely due to the parasite and probably weight loss. I want to review that too. But I'm pretty sure E. histo causes that. I will talk to you later. I need to cook dinner. I'm not sure If I can read those things tonight but if not tomorrow.
mkh9
1415174 tn?1453246703
COMMUNITY LEADER
Ok, I wanted to add regarding Entamoeba histolytica.  With chronic infection you can get pain, diarrhea, discomfort in the abdomen, Weight Loss, and fatigue, 90% can become asymptomatic carriers. Sometimes it can go to the liver and cause an abcess and cause & pain in the upper right abdomen. Then you would have weight loss, fever,& tender liver. So I think most of your problems are from the E. histo. I'll write more tomorrow.
take care,
mkh9
Avatar universal
Thank you  very much for your answer. it is a pleasure reading you.

what do you mean by severe wasting of the muscles? well in the arms area they got smaller. but on the legs area my upper and lower leg became much thiner. this happened in a period of 3 months more or less.

Well I hope that the loss of appetite is caused by the E. histo. but I took medication for it, maybe it is still in my body.

Do you think I could have a bacteria? like straph or strep?

Enjoy your dinner :) thx

1415174 tn?1453246703
COMMUNITY LEADER
Hi, I meant severe wasting of the muscles is like they have really shrunk a lot very small and atrophied. I don't think you have that. Have you done a lot less activity in that period or over time? Due to my inactivity (I sit around too much due to my back pain) my muscles have gotten smaller too.  It doesn't take long for that to happen. Yes I'm sure it is the E. histo causing your appetite problems and more. I don't think the Progesterone is that far off of normal and I don't think it is causing hair loss. Do you have hair loss in your family because it can be genetic and it can happen really early in life. No I don't think you have a bacterial infection . I would worry that the E. histo may have gone into the liver. Your fever may be due to an abcess from it going there. Can you get a scan that would check for that? Has your fever gone away? Why do you think you have a bacterial infection? I read your link reagarding the immunoglobulin level. It is pretty much what I thought. You can have a high Immunoblobulin level while you have a chronic infection (I.e your parasitic infection). The test can look for Chronic lymphocytic leukemia but that would show up on the complete blood count, cirrhosis of the liver (unless you have hepatitis or are an alcoholic I don't think you need to worry about this since you were checked for Hep. You were checked for many autoimmune diseases , one thing it can check for is multiple myeloma. But I don't see you have symptoms of that. So, it could check for general immune status if that is what you want you can do it If it will make you feel better but you had your CD4/CD8 done and the ratio was normal! So that is great. I don't see anything else wrong other than the hair loss, the other levels are not high enough to worry about (progesterone) and the parasite is the main problem. I forgot the treatment you are on but it should be 5-10 days of metronidazole (flaggyl) and then 10 days of either paramomycin or diloxanide fariate,  The diloxanide isn't used in the US as it can cause hearing damage. BTW, you were tested for Strep group A by the ASO test and Methacilllin resistant Staph aureus (MRSA) and they negative.
mkh9
Avatar universal
Many thanks for your answer.
I just got back my stool analysis and they didn't find any parasites or cysts. looks like the 4 days medication course worked. but if I do not have the E.hystolitica anymore why I have an appetite loss? is it possible that it wasn't detected this time?

I lost mainly fat from my upper and lower legs, I still have muscles on them but they became smaller as well as on my arms.

The fever of 98.6 farenheit lasted for 7 days and it came just after I noticed my white tongue, like a day or two. And I also lost my appetite, I used to feel hungry quite often.

I have another medication that combines metranidazol and diloxinde should I take it?

The test for MRSA they took a swab from my armpit. is this how it is done? I also took Defucin (fucidic acid) 250 mg x3 a day for 6 days
Avatar universal
should I do an endoscopy?
1415174 tn?1453246703
COMMUNITY LEADER
No, I think they do an MRI for the liver or maybe a CT. You have to ask the doctor on that one.
mkh9
1415174 tn?1453246703
COMMUNITY LEADER
Yes, that is good that the parasite is clearing up. But some stay in the lumen of the intestine and so I would wait a few days and get retested. Then if still negative maybe a week or so. Didn't the doctor give you directions on how often to test after the antibiotic they gave you?. Which antibiotic did they give you to take? I think the recommendation is two antibiotics I mentioned. I wouldn't take it on your own there can always be complications. I would ask them about it and that you are worried about recurrances. The temperature of 98.6 is not a fever it is normal for Farenheit. You may still not feel well because the parasite can cause some temporary damage to the intestine I think. There are more than one parasite they produce more. But hopefully, the drug did the job. If you didn't have a fever (since 98.6 or 98.7 are normal) then you probably don't have a liver abscess. I would discuss with your doctor about your loss of appetite and corresponding weight loss. I am sure they are related to the parasitic infection but they may be able to give you something for it. Didn't you already take Metronidazole or what med did you take. I can't find it with all these messages. Did the doctor give you that one or did you buy it over the internet or pharmacy on your own? Regarding the MRSA yes they take it with a swab. Did you have a boil or sore under the arm? I don't know the drug Dufucin. Also, these drugs can cause loss of appetite sometimes so we'll see if you improve.
mkh9
Avatar universal
This is the drug that the doctor prescibed for 3 days, i took it for four days, it is called fladazol: it has Secnidazole.

http://www.amoun.com/index2.php?page=shop.product_details&flypage=flypage.tpl&product_id=143&category_id=32&option=com_virtuemart&Itemid=59

I finished my prescription like 10 days ago. So todays stool analysis result was like 10 days after taking this medication. the doctor had told me to retest 7 days after taking the medication.

Now I am thinking of taking a combination of metronidazole and diloxanide floride for 5 to 10 days. the doctor didn't tell me to take any other drugs. but I think this drug could be good to eliminate any in the lumen of the intestine. what do you think?

I took Defucin 250 mg tablets by my own
http://en.wikipedia.org/wiki/Fusidic_acid
Avatar universal
i was mentionning endoscopy as it may reveal why I have a loss of appetite.
Avatar universal
I also just had the results of Candida culture in stools.

And I got this result which I do not understand.

"Growth of Candida spp. [non albicans] which is resistant to all antibiotics"

What does this mean
1415174 tn?1453246703
COMMUNITY LEADER
No, I think it is from the parasite or the antibiotics you took and/or the disruption of the normal flora see below.
mkh9
1415174 tn?1453246703
COMMUNITY LEADER
No, the Fladazol and Secnidazole are good for getting rid of amoeba and it looks like it is doing its job. I wouldn't take any more antibiotics. You can repeat your stool test in another 10 days and see if it is still gone. But now you have yeast that took over because of the antibiotics that wiped out your normal bowel flora. This may also be one of the reason for you not having an appetite and maybe the constipation. I would talk with your doctor. But, you need to take some probiotics. Get some live probiotic pills that contain active culture like 10 to the 8th 10E8 bacteria of lactobacillus sp, Bifidobacteria sp. the more variety of good bacteria the better and see if that helps. Take it for a month or two. Keep drinking a lot of water. About 8 glass a day or a combination of herbal tea and water , whatever you drink but stay hydrated. The fact that the Candida sp. is resistant at this point I'm not sure that it matters you are not going to treat the candida except by diluting it out by eating other bacteria basically. You can add eating a couple of yogurts a day that contain live bacteria. What country do you live it? Do they have yogurt like Yoplait or one that has active bacteria? you will eventually also get it from your food too. But, no more antibiotics unless the doctor tells you to. Get your stool retested for yeast in about a month? It takes a while. you can try sooner like 10 days but it probably will take longer.
mkh9
1415174 tn?1453246703
COMMUNITY LEADER
If all else fails there is a research way that works to get your fecal flora back but it sounds gross. But first try the food way. Then we can talk about the other way.
mkh9
Avatar universal
You think my white tongue can be caused by this candida I have? can it cause the hair loss I am experiencing?
shouldn't I take Fluconazole as well with probiotics?

Which doctor should I consult for this, a GI?

I think we have Activia yogurt. do you know it?
Avatar universal
or should I go to a pathologist?
1415174 tn?1453246703
COMMUNITY LEADER
Well you said your tongue didn't have yeast but if it does I would say yes probably. At this point no more antibiotics until you get your intestinal flora back to normal. You are lucky you didn't get Clostridium difficile toxin. Yes I think Activia has it. I would eat two of those a day. But I buy some real probiotics. The last time I was given several antibiotics the nurse told me to take probiotics so I bought some from Costco called Trunature digestive probiotic. It had 10 billion active cultures. You take 1 capsule a day. It won't hurt to eat the yogurt too, unless your counting calories or can eat milk products. I think it will restore itself on its own. I would just go to a good family practice doctor if you have one you like. But I haven't ever had any doctor give me probiotics (it was the nurse that prevented me from getting C. difficile not the doctor). I was wondering why the doctor hadn't recommended it. It seems like they just treat whatever problem comes up. So I would still take the probiotic if I were you. Pathologists generally just work with the laboratory. They look at slides and see if people have cancer and do autopsies etc. A GI doc would ok too. Which doctor told you about the yeast?
mkh9
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