Recurrent Miscarriages

[bny807]

Hello - me and my husband have been undergoing fertility treatments for almost a year now (since a lap that discovered i had severe endometriosis and removal of one ovary). They have since discovered my husband has poor morphology (2% kruger) and i have mild pcos.. We have gotten pregnant twice via IUI and follistim, however miscarried both times. The first time no bleeding at all and diagnosed with a blighted ovum, finally began to bleed at 10 weeks. The second one i started spotting and bleeding at 5 weeks, however my beta doubled every 26-30 hours regardless of the bleeding (even though i was on supplemental progesterone it dropped from the 40's at 4weeks preg, to 10 when the bleeding was occuring, but began to rise as we increased my dose but miscarried anyways)
   My question is How likely is it that a clotting disorder or genetic factor caused both of these since they were both so different from each other? If it was from one problem/factor, wouldn't the miscarriages be more similiar in occurance?  We are awaiting genetic testing, but my RE wants us to wait a full two months from the time my beta went to 0 so it won't interfere with the clotting tests, however its been 1.5 months and are debating continuing with the follistim in one week regardless of the testing. Thanks so very much for your time and help!

[cc1222]

Hi, I'm 29 yrs old, did IVF twice this year. First & 2nd time got pregnant with no problem, got to about 7 weeks and heartbeat decreased, 2nd time miscarried. Did pregnancu loss testing all came back negative. Had a biopsy and tested positive for urethritis. My Dr is putting me & my husband on Doxycycline to clear up the infection. Could this be the cause of both my miscarriages?? If I get preganant again, could the urethritis come back & cause a miscarriage again??

[bny807]

Thank you very very much for your time! its very much appreciated!

[John Kim, M.D.]

I doubt genetic or clotting disorder. But it would not hurt to do the work up for peace of mind to make sure.
The good news is that if you had 2 miscarriages the likelihood you will have a 3rd is no higher than for any other person ie about 20%.
I would agree with your RE to wait.