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1503643 tn?1311521838

Can thyroid cancer turn into lymphoma?

can thyroid cancer turn to lymphoma? Or can you go into remission from thyroid cancer and then get lymphoma? Is it possible to have them both? This is very confusing.

What are the probabilities of the mentioned scenarios?
23 Responses
1081992 tn?1389907237
COMMUNITY LEADER
Hi, it's just a pure guess but I'd think that the lab tech was only following policy. I wonder if you could shop around for the flow cytometry. E.g., I'd bet that you can similarly bargain with PET scan businesses.

If I were you, I'd get a copy of that path report asap. The adjectives might be revealing.

Also, there a pathologist who put up hundreds of videos on youtube, showing specimens while giving descriptions. He also now has a website somewhere. Once you understood everything, I'd try a call to the pathologist who did your report.

Are you familiar with why flow cytometry would be done? (the antibodies, etc)

As far as the hip/thigh nodes, I guess they are simply reactive (i.e., doing their immunity job).. Have you had thrush? Burning eyes? Do you get a bad reaction a day or so after consuming sugar? Have you taken yogurt as an anti-candida measure?

As for your C) needle quoted above, I don't quite follow - since it says it was ostensibly taken from a node yet only blood was in the sample. Even so there is no mention of deranged/abnormal shaped lymphocytes.

1081992 tn?1389907237
COMMUNITY LEADER
Hi. Unfortunately, there is an increased risk for lymphoma after thyroid cancer, That might result from the treatment used earlier, especially radiation. But risk can also be increased from some anti-cancer drugs. Or it can even be because a person has a predisposition, because of their genes or maybe something in their environment.

Here's a paper that talks about the increased risk after thyroid cancer:
http://www.endocrine-abstracts.org/ea/0009/ea0009oc35.htm

It gives the risk for a second cancer as being 1.31 times the risk for people in general. But it doesn't give a number for lymphoma in particular. So that's 31% more likely.

On the other hand, you might consider that some lymphomas are classified as 'indolent', meaning very slow growing. Follicular lymphoma can be that way.

Did a pathologist say that your cells look like lymphoma cells under a microscope? Are you waiting for further testing to be done, such as flow cytometry?
1503643 tn?1311521838
Back in April my endocrinologist said that I no longer have thyroid cancer that it looked like a lymphoma(after a needle biopsy). I had a surgical biopsy removing another lymph node in my neck and they told me that it was a virus.  The pathology reports said lymphoid dysplasia, and lymphoid proliferation.

At that point...I was beginning to have trouble with my left hip and thigh. I could feel small nodes where the pain was...but nothing pathological.  Now...the nodes on my left side are becoming more troublesome and a little bigger. But still not very big. I just deal with pain from them.  I also have a walnut where my thyroid used to be and and swollen lymph node near my carotid artery.  I had cancer removed from that area before.

Thanks for the info.
1081992 tn?1389907237
COMMUNITY LEADER
Well, the word 'dysplasia' seems like good news, doesn't it? Plus, I saw your pathology report elsewhere and it says, "No malignancy is present".

Dysplasia means abnormal cells, not cancer. Did it say low grade or high grade? Dysplasia does not necessarily mean it will progress to cancer.

I'd guess the one doc says it was a virus because of the presence of macrophages in the biopsy. Maybe the endocrinologist has been unnecessarily alarming you. One thing that seems to be true is that you do not have a definite diagnosis of lymphoma, but that something unusual is going on.

Also, why do you say that they are nodes on your hip? Did any doctor say that? I could be wrong, but I don't think there would be any actual lymph nodes at that spot.

Btw, I know somebody who had swollen lymph  nodes, non-cancer, for longer than 9 months.
1503643 tn?1311521838
A couple of weeks ago. I went to a friend of mine who is an ER doc. He palpated the lumps(very small) that start on the left side of my hip(closest to the hip bone) and periodically go all the way down to the upper left thigh. He said that they felt like lymph nodes and with my history...I shouldn't waist time getting them checked out.  So I went to my PCP who said(after feeling the hard lumps on my left side) that we need to rule out lymphoma/leukemia. He did an ultrasound for free cause I don't have insurance. He could see the lymph nodes but said nothing stood out to him.  He also did an X-Ray to rule-out the arthritis causing problems(I have arthritis in my spine from crushing discs in my back when I was younger)He said that the X-Ray looked fine. I looked at it also and could not see anything unusual except maybe a small nodule on the top of the left hip.  It was too small to really tell.

Because of the hard mass/s in my neck...i'm wondering if this isn't just another reoccurance of the thyroid cancer.

This is good news that you know someone with swollen lymph nodes for longer than 9 months. Starting to wonder if this just isn't gonna be par for the course for me.  With all of the surgeries and lymph node removals.  I'm bound to have some kind of repercussions from it.

If it weren't for the night sweats and the masses that are causing me pain and discomfort in some areas...not all...I would think this is a virus. But things are gradually getting worse. I think the fact that things are moving slowly is on my side. Just hope that we figure it out sooner rather than later.
Thank you Ken! I appreciate your knowledge on the subject.  It makes me feel better knowing that dysplasia doesn't necessarily mean cancer.
1081992 tn?1389907237
COMMUNITY LEADER
>> It makes me feel better knowing that dysplasia doesn't necessarily mean cancer.

It's better than that. They didn't find any cancer at all. Check your pathology report to see if it says 'low grade' dysplasia - which is the type that's known to almost never turn into cancer.

Night sweats? Do you have to change your clothes and bed sheets because they're soaked? That's what is meant. (And an infection can indeed cause night time sweating.)

Okay, by hip I'd thought you'd meant the outer hip bone, the one that you can slam into a wall (the greater trochanter). But yes, the node location that you describe would be included in the inguinal group of nodes, I believe.

Re-occurance of the thyroid cancer? Your pathology report says, "No thyroid parenchyma is present". The parenchyma is the body of the gland. So that seems to me to say that the thyroid hasn't grown back, not in the area where the needle was inserted. Plus, there were no thyroid cancer cells. Instead, the masses in your neck are apparently made of those abnormal lymphoid cells. Your sample B showed a few acinar cells, which might be from a salivary gland. (Acinar means 'many lobed', like for instance a blackberry.) That's the usual structure/shape of those glands. Maybe the needle passed through a salivary gland on its way to the target area.

How's this for a theory: the radiation that you received for the thyroid cancer had the side effect of making the DNA of some of your lymphocytes get out of whack. They are abnormal and are proliferating, but are not cancer. Then, you get some mystery infection. Either it's from a virus, which won't be helped by antibiotics - or else it could be some bacteria that is resistant to all the different antibiotics you've had -  or else it could be a fungus or parasite.

Did you go to any foreign countries in the past few years? That might explain a parasite. Did you change where you live? That might have put you into contact with some health threat. Have you been to the Ohio Valley?

Having the inguinal nodes in a chain seems to me to be more likely from infection than lymphoma.

So, you get the mystery infection and that stirs up your immune system. Your immune system reacts strangely because it's got all those abnormal lymphocytes. So the areas in your neck are stimulated chemically and grow somewhat quickly - but are not cancer. Your immune system also can't seem to defeat the infection, because it is weakened. Have you had super stress in the last year? (Okay, that might obviously be a stupid question... sorry  :)

It sounds like you've had some very rough years. You must be very brave to have weathered it all. Keep up the good work :)





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