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Immature Platelet Fraction and Immature Granulocyte Absolute
My immature platelet fraction is 0 compared to normal range of 1-6.3% (LOW) and immature granulocyte absolute is 0.02 compared to a normal range of 0-0.05/mm3 (HIGH). Can anyone help explain what these 2 components mean and whether or not it is of concern. One doc seemed to think it was fine but that was a rushed phone conversation that he turned into a surgeon referral....not an answer for me unless you know what needs surgery (he is suggesting exploratory surgery, have had enough of that guess work in my past). Everything else looked to fall into 'normal' ranges except my Albumin was a tiny bit high at 5.1 and so my Alb/glob ratio was a 2.2, teeny tiny little high. Potassium continues to run low to below normal ranges even on potassium foods and supplements. Any input is greatly appreciated, ALWAYS. thanks!
Hi there californiawoman298, I am sorry I am just now reading this as I have been up against a health crisis for another family member and away from this site. I genuinely am baffled about these tests and what they mean and had a horrible time trying to find info where I am usually very good at tracking down things and understanding them. But Ken is very helpful and informed so I would try directing a question or two right to him and see if he is available to answer or try to explain something for you. I am learning, as hard as it may be for me, to not jump to the very worst conclusion as it is all that more hard on my health (the unnecessary stress of worry). But I first hand KNOW that is easier said than done. so I encourage you to continue to advocate and research about your health but try not to allow your mind to go straight to the worst case scenario.
I personally have no current updates, but I go to a surgeon tomorrow and am hoping he will do a bit more details imaging on some things for me and some more blood work I will update, probably on my journals when I know more.
Have you found out any more yet? I pray your health improves and your docs pay attention to what is needed.
Blessings,
Rhonda
I personally have no current updates, but I go to a surgeon tomorrow and am hoping he will do a bit more details imaging on some things for me and some more blood work I will update, probably on my journals when I know more.
Have you found out any more yet? I pray your health improves and your docs pay attention to what is needed.
Blessings,
Rhonda
2 Comments
I know this thread is old, but I recently had a CBC done (haven't had my follow up appointment yet) and my IPF was 0.0% .. everything else was normal with the exception of the RDW being 37.8 compared to a normal range of 38.5-54.4 fL.. also my immature granulocyte absolute count was 0.03% compared to a normal of 0.0%... I've been having a lot of mystery health issues and am having a hard time finding answers.. just curious to any insight you may have.
short answer: possible MCAD
Any updates?
My cbc was normal except for 1% immature granulocytes and .1 immature granulocytes absolute.
Everything I read says cancer. My doc just told his nurse to tell me to repeat the CBC in about a month. I'm worried.
My cbc was normal except for 1% immature granulocytes and .1 immature granulocytes absolute.
Everything I read says cancer. My doc just told his nurse to tell me to repeat the CBC in about a month. I'm worried.
Oh, gotcha. Yes, my potassium is regularly low without knowing a cause. So I do take supplements but I stick with very low otc doses and food sources. The hospital rx'd me a super high dosage temporarily. Hopefully this new doc will consider another rx with monitoring my levels.
I have been know to use baking soda moderately, espesh once I learned of the long term consequences of using antacids and proton pump inhibitors...but also knowing that my urine ph has run high frequently.
Back to the ph, did you have in mind a connection with it to the other pieces to my puzzle?
I feel like I am too close to the forest to see the trees sometimes with this whole thing. but the connective tissue disease thing seems to fit so well.
And like I mentioned to someone else on here I have to remember that I could also be dealing with a couple of separate illnesses.
I have been know to use baking soda moderately, espesh once I learned of the long term consequences of using antacids and proton pump inhibitors...but also knowing that my urine ph has run high frequently.
Back to the ph, did you have in mind a connection with it to the other pieces to my puzzle?
I feel like I am too close to the forest to see the trees sometimes with this whole thing. but the connective tissue disease thing seems to fit so well.
And like I mentioned to someone else on here I have to remember that I could also be dealing with a couple of separate illnesses.
COMMUNITY LEADER
Sorry, I meant K as in potassium. Potassium citrate has been used in studies to alkalinize. Baking soda does that too, but at the risk of the powerful laxative effect.
By all means, it sounds as if you should try lots of leafy greens, etc. With so many people on coumadin there must be dozens of web pages with lists of high vit K foods, plus lists of things that are blood thinners (not only fish oil and vit E, even cinnamon and ginger et al, have an effect).
There are also vit K supplements, as you probably know, with K1 being from plants and K2 from animals, IIRC.
By all means, it sounds as if you should try lots of leafy greens, etc. With so many people on coumadin there must be dozens of web pages with lists of high vit K foods, plus lists of things that are blood thinners (not only fish oil and vit E, even cinnamon and ginger et al, have an effect).
There are also vit K supplements, as you probably know, with K1 being from plants and K2 from animals, IIRC.
I know, Ken. Exactly. I thought that was a typo too! But that is really what it says on my work up sheet....those numbers and the the letter "H" next to it for "high". I stared at it and re read it I don't know how many times b/c I thought since I get so foggy sometimes I was just not reading it right, LOL. But that is what it says which is also one of the reasons I decided to ask about these details on here. I couldn't find anything really in my searching on the internet. So your info is really helpful.
My urine ph seems to really waver quite a bit, more often being to the high acidic side.
I actually have considered vitamin K deficiency. But nobody has tested it yet. Is that what you meant? Vitamin K deficiency? I bleed easily with no real explanation for why from the docs and I've been deficient in other things now so I considered it....especially because at one point I started eating asparagus daily and it seemed to make me feel better. I then looked up the nutrients of it and it appears to be full of vitamin K. I really should eat it daily, since it seemed to make me feel better.
Yes, my problems remain, still a mystery. Some kinda good days, some not so good, but I just keep trying to do what I am called to do amidst it all.
It could be simply a "thorn in my side" that I may never find a physical reason for this side of heaven but God knows how I like to solve things :)
so I will likely keep trying to figure it out.
As for now, I have an appointment with a 'surgeon' whose office says they will run some tests that haven't been done yet in order to try to diagnose me rather than any surgery. I was afraid my gastro doc was sending me to him for exploratory surgery. But when I talked to the folks at the office they assured me that was not the case. if this dude will run more NON invasive tests to try to piece this puzzle together I welcome that.
And I will certainly keep this message board posted and updated as best I can. If my willingness to share my info helps even just one person somehow it will be well worth it!
So, what is your thinking on the ph thing, related to K deficiency???? Or what?....when you have time, of course. You have been generous with your time.
Thanks yet again.
My urine ph seems to really waver quite a bit, more often being to the high acidic side.
I actually have considered vitamin K deficiency. But nobody has tested it yet. Is that what you meant? Vitamin K deficiency? I bleed easily with no real explanation for why from the docs and I've been deficient in other things now so I considered it....especially because at one point I started eating asparagus daily and it seemed to make me feel better. I then looked up the nutrients of it and it appears to be full of vitamin K. I really should eat it daily, since it seemed to make me feel better.
Yes, my problems remain, still a mystery. Some kinda good days, some not so good, but I just keep trying to do what I am called to do amidst it all.
It could be simply a "thorn in my side" that I may never find a physical reason for this side of heaven but God knows how I like to solve things :)
so I will likely keep trying to figure it out.
As for now, I have an appointment with a 'surgeon' whose office says they will run some tests that haven't been done yet in order to try to diagnose me rather than any surgery. I was afraid my gastro doc was sending me to him for exploratory surgery. But when I talked to the folks at the office they assured me that was not the case. if this dude will run more NON invasive tests to try to piece this puzzle together I welcome that.
And I will certainly keep this message board posted and updated as best I can. If my willingness to share my info helps even just one person somehow it will be well worth it!
So, what is your thinking on the ph thing, related to K deficiency???? Or what?....when you have time, of course. You have been generous with your time.
Thanks yet again.
COMMUNITY LEADER
Glad to have been of help, Rhonda. But your overall problems remain.
And this: "immature granulocyte absolute is 0.02 compared to a normal range of 0-0.05/mm3 (HIGH)."
a typo? 0.02 is within the range you mention
If you mean there is something like a "left shift" then that usually results from infection, as new cells get rushed into production.
Low K? How is your urine pH? Just a thought.
And this: "immature granulocyte absolute is 0.02 compared to a normal range of 0-0.05/mm3 (HIGH)."
a typo? 0.02 is within the range you mention
If you mean there is something like a "left shift" then that usually results from infection, as new cells get rushed into production.
Low K? How is your urine pH? Just a thought.
COMMUNITY LEADER
...then again, you are at the high end of normal, tending to say there are a lot of new ones.
COMMUNITY LEADER
Yes, so with with 2 out of 3 levels being in a good range, I suppose most docs won't get alarmed. Platelets usually get born big, then get smaller over time.
With IPF usually used to determine why a patient has low platelets (either destruction or else lack of production), I don't know why the doc ordered that test for you... unless just being super thorough.
Having high IPF with low platelet count would tend to mean that they are being destroyed and production is ramped up to compensate. Conversely, low IPF with low count would tend to mean they are not being produced.
Low IPF with a normal count? I don't know.
With IPF usually used to determine why a patient has low platelets (either destruction or else lack of production), I don't know why the doc ordered that test for you... unless just being super thorough.
Having high IPF with low platelet count would tend to mean that they are being destroyed and production is ramped up to compensate. Conversely, low IPF with low count would tend to mean they are not being produced.
Low IPF with a normal count? I don't know.
COMMUNITY LEADER
Yes, having a normal platelet count tends to nullify any alarm over the low IPF.
What was your MPV?
What was your MPV?
Hi Ken,
Yes, the platelet count reads 274 in a normal range of 140-440, so that's good, right?
Yes, the platelet count reads 274 in a normal range of 140-440, so that's good, right?
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