Higher Lactate Dehydrogenase LDH needs help interpreting

[rockla]

I'm HbsAbg Positive but my HbsAg Antigen is negative and Anti Bodies are reactive which is good

HBeAg-Hepatitis B Envelope Antigen
(Serum,CMIA)                          NON REACTIVE(0.41) S/CO Non Reactive: = 1.0
Anti HBe-Ab to Hepatitis B Envelope Ag
(Serum,CMIA)   REACTIVE(0.25) Ratio Non Reactive: > 1  Reactive:  250.00) IU/mL Non Reactive: < 0.05


Prothrombin Time (PT)
(Citrated plasma)
Prothrombin Time 14.0 sec 11-16
Control (MNPT) 13.6 sec --
Ratio 1.03 --
Index 97.14 % --
PT(INR) Value 1.04 -- Normal Population : 0.8 - 1.2 Standard Therapy: 2.0-3.0 High Dose Therapy: 3.0-4.5

[fntn]

If the cause is found and changed or stopped, then your LDH levels will drop to normal in a short time, a week or two. So if it was your strenous exercise that caused a lot of muscle tissue breakdown, then a more modest routine should do the trick.

[rockla]

Thanks Man this is very motivating , yeah recently i was doing some exercise  for last 2-3 days and my body was paining as i started exercise recently after so many years maybe that could be the reason.Just a quick question can that LDH go down with some medicine ? Since all LFT looks good or it could be due to physical exercise ?

[fntn]

Looking at your posted serum data, it appears that your liver is quite happy right now. Both your synthesis and excretory function levels are normal, your A/G ratio is nicely balanced and your liver function enzymes are normal as well. So if your elevated LDH level has caused you concern wrt your liver, you can relax, all appears good.

LDH is a very generalized enzyme that marks tissue damage throughout your body. Every cell, from head to toe, will produce it to some degree. The half-life of LDH will vary depending on its cellular source, but a good average number to use is about 3 days or so. That means that you current high level of LDH has been caused by something that recently happen - that is of course, if your LDH levels were normal before this measurement. If it has been persistently high, then its cause is a mystery and you need to consult your doctor. Simple muscle strain, anemia, etc can cause it.

Take care!

[rockla]

Investigation Observed Value Unit Biological Reference Interval
Proteins
Total Protein
(Serum,Biuret) 7.51 g/dL 6.4-8.3
Albumin
(Serum,Bromocresol green)4.25 g/dL 3.5-5.2
Globulin
(Serum) 3.26 g/dL 1.8-3.6
A/G Ratio
(Serum) 1.3 1.1-2.2
BilirubinTotal, Direct, IndirectSerum
Bilirubin-Total
(Serum,Diazo) 0.53 mg/dL 0.2-1.2
Bilirubin-Direct
(Serum,Diazo) 0.19 mg/dL 0.0-0.5
Bilirubin- Indirect
(Serum,Calculated) 0.34 mg/dL 0.1-1.0
SGOT (AST)
(Serum,Enzymatic) 27 U/L 0-35
SGPT (ALT)
(Serum,Enzymatic) 27 U/L 0-45
Gamma GT (GGTP)
(Serum,Enzymatic) 19 U/L 12-64
Alkaline Phosphatase
(Serum,pNPP) 77 U/L 40-150
LDH-Lactate Dehydrogenase
(Serum,Enzymatic) 274 U/L 125-220
HBsAg Screening
(Serum,CLIA) REACTIVE(> 250.00) IU/mL Non Reactive: < 0.05