Your indirect (unconjugated) bilirubin is elevated and that doesn't generally suggest a liver disease. Significant elevations of direct (conjugated) bilirubin are often associated with liver disease but your labs do not indicate that your direct bilirubin is significantly elevated so it does not appear that have a liver disease.
Often Gilbert's Syndrome is the cause of elevated indirect bilirubin.
By Mayo Clinic staff
Gilbert's syndrome is a common, mild liver condition in which the liver doesn't properly process a substance called bilirubin. Bilirubin is produced by the breakdown of red blood cells.
Gilbert's (zheel-BAYRZ) syndrome typically is harmless and doesn't require treatment.
Gilbert's syndrome is caused by an inherited gene mutation. You're born with Gilbert's syndrome, though it often goes undiscovered for many years. Gilbert's syndrome is often discovered by accident, such as when you have a blood test that shows elevated bilirubin levels.
Gilbert's syndrome is also known as constitutional hepatic dysfunction and familial nonhemolytic jaundice.
By Mayo Clinic staff
The lone sign of Gilbert's disease is that your skin and the whites of your eyes occasionally have a yellowish tinge (jaundice). This is caused by the slightly elevated levels of bilirubin in your blood. Some conditions and situations may increase bilirubin levels, and thereby jaundice, in people with Gilbert's syndrome. These include:
Illness, such as a cold or the flu
Fasting or eating a very low-calorie diet
Lack of sleep
The jaundice will go away when these conditions resolve.
When to see a doctor
Make an appointment with your doctor if you experience jaundice. Jaundice has many possible causes.
Lifestyle and home remedies
By Mayo Clinic staff
Certain life events, such as stress, can trigger episodes of higher bilirubin levels in Gilbert's syndrome, leading to jaundice. Doing what you can to manage those situations can help keep bilirubin under control.
These steps include:
Tell every doctor about your Gilbert's syndrome. Gilbert's syndrome affects the way your body processes certain medications. This has the potential to worsen side effects. Tell each doctor you visit that you have Gilbert's syndrome, so any medications can be selected with this in mind.
Eat a healthy diet. Choose a healthy diet full of fruits and vegetables. Avoid extremely low-calorie diets. Stick to a routine eating schedule and avoid fasting or skipping meals.
Manage stress. Find ways to deal with the stresses in your life. Consider exercise or quiet time alone to cope with stress.
Another possible cause of elevated indirect bilirubin is hemolytic anemia. This occurs when there is a premature destruction of red blood cells which causes a build-up of unconjugated/indirect bilirubin in the blood. There are some medications that can cause hemolytic anemia so you might search all medications you currently take to determine whether any have a side effect of hemolytic anemia.
Generally Gilbert's Syndrome is considered a benign condition and requires no treatment. Frequently it is diagnosed by chance on the basis of routine blood work.
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